Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis.

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Title: Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis.
Authors: Schillemans T; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Tragante V; Division Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., Maitusong B; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Gigante B; Division of Cardiovascular Medicine, Department of Medicine, Danderyd University Hospital, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Sciences, Danderyd University Hospital, Karolinska Institutet, Stockholm, Sweden., Cresci S; Cardiovascular Division, John T. Milliken Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, United States., Laguzzi F; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Vikström M; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Richards M; Department of Medicine, Christchurch Heart Institute, University of Otago, Christchurch, New Zealand.; Cardiovascular Research Institute, National University of Singapore, Singapore, Singapore., Pilbrow A; Department of Medicine, Christchurch Heart Institute, University of Otago, Christchurch, New Zealand., Cameron V; Department of Medicine, Christchurch Heart Institute, University of Otago, Christchurch, New Zealand., Foco L; Institute for Biomedicine, Eurac Research, Bolzano, Italy., Doughty RN; Heart Health Research Group, The University of Auckland, Auckland, New Zealand., Kuukasjärvi P; Finnish Cardiovascular Research Center - Tampere, Department of Cardio-Thoracic Surgery, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Allayee H; Department of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States., Hartiala JA; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States., Tang WHW; Department of Cardiovascular and Metabolic Sciences and Center for Microbiome and Human Health, Lerner Research Institute, Cleveland Clinic Ohio, Cleveland, OH, United States.; Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic Ohio, Cleveland, OH, United States., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories Ltd., Tampere, Finland.; Finnish Cardiovascular Research Center - Tampere, Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Nikus K; Finnish Cardiovascular Research Center - Tampere, Department of Cardiology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Heart Center, Department of Cardiology, Tampere University Hospital, Tampere, Finland., Laurikka JO; Finnish Cardiovascular Research Center - Tampere, Department of Cardio-Thoracic Surgery, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Heart Center, Department of Thoracic Surgery, Tampere University Hospital, Tampere, Finland., Srinivasan S; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom., Mordi IR; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom., Trompet S; Department of Internal Medicine, Leiden University Medical Center, Leiden, Netherlands.; Section of Gerontology and Geriatrics, and Department of Cardiology, Leiden University Medical Center, Leiden, Netherlands., Kraaijeveld A; Division Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., van Setten J; Division Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., Gijsberts CM; Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.; Department of Cardiology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands., Maitland-van der Zee AH; Amsterdam University Medical Centers, Department of Respiratory Medicine, University of Amsterdam, Amsterdam, Netherlands., Saely CH; Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.; Private University in the Principality of Liechtenstein, Triesen, Liechtenstein.; Academic Teaching Hospital Feldkirch, Feldkirch, Austria., Gong Y; Center for Pharmacogenomics and Precision Medicine, Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL, United States., Johnson JA; Center for Pharmacogenomics and Precision Medicine, Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL, United States.; Division of Cardiovascular Medicine, College of Medicine, University of Florida, Gainesville, FL, United States., Cooper-DeHoff RM; Center for Pharmacogenomics and Precision Medicine, Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL, United States.; Division of Cardiovascular Medicine, College of Medicine, University of Florida, Gainesville, FL, United States., Pepine CJ; Division of Cardiovascular Medicine, College of Medicine, University of Florida, Gainesville, FL, United States., Casu G; Azienda Ospedaliero Universitaria, Sassari, Italy., Leiherer A; Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.; Private University in the Principality of Liechtenstein, Triesen, Liechtenstein., Drexel H; Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.; Private University in the Principality of Liechtenstein, Triesen, Liechtenstein.; Department of Medicine and Intensive Care, County Hospital Bregenz, Bregenz, Austria., Horne BD; Intermountain Medical Center Heart Institute, Salt Lake City, UT, United States.; Division of Cardiovascular Medicine, Stanford University, Stanford, CA, United States., van der Laan SW; Central Diagnostics Laboratory, Division Laboratories, Pharmacy, and Biomedical Genetics, University Medical Center Utrecht, Utrecht, Netherlands., Marziliano N; Medicine Laboratory Unit, ASST Rhodense (Rho-Milano), Lombardy, Italy.; Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy., Hazen SL; Department of Cardiovascular and Metabolic Sciences and Center for Microbiome and Human Health, Lerner Research Institute, Cleveland Clinic Ohio, Cleveland, OH, United States.; Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic Ohio, Cleveland, OH, United States., Sinisalo J; Heart and Lung Center, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Kähönen M; Finnish Cardiovascular Research Center - Tampere, Department of Clinical Physiology, Faculty of Medicine and Health Technology, Department of Clinical Physiology, Tampere University, Tampere, Finland.; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories Ltd., Tampere, Finland.; Finnish Cardiovascular Research Center - Tampere, Department of Clinical Physiology, Faculty of Medicine and Health Technology, Department of Clinical Physiology, Tampere University, Tampere, Finland., Lang CC; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom., Burkhardt R; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany.; LIFE Research Center for Civilization Diseases, Leipzig University, Leipzig, Germany., Scholz M; LIFE Research Center for Civilization Diseases, Institute for Medical Informatics, Statistics and Epidemiology, Leipzig University, Leipzig, Germany., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, Netherlands.; Netherlands Heart Institute, Utrecht, Netherlands., Eriksson N; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden., Åkerblom A; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden., James S; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden., Held C; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden., Hagström E; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden., Spertus JA; Saint Luke´s Mid America Heart Institute, University of Missouri-Kansas City, Kansas City, MO, United States., Algra A; Department of Neurology and Neurosurgery, Brain Centre Rudolf Magnus and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands., de Faire U; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Åkesson A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Asselbergs FW; Division Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.; Faculty of Population Health Sciences, Institute of Cardiovascular Science and Institute of Health Informatics, University College London, London, United Kingdom., Patel RS; Faculty of Population Health Sciences, Institute of Cardiovascular Science and Institute of Health Informatics, University College London, London, United Kingdom.; Bart's Heart Centre, St Bartholomew's Hospital, London, United Kingdom., Leander K; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Source: Frontiers in physiology [Front Physiol] 2022 Jun 23; Vol. 13, pp. 909870. Date of Electronic Publication: 2022 Jun 23 (Print Publication: 2022).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101549006 Publication Model: eCollection Cited Medium: Print ISSN: 1664-042X (Print) Linking ISSN: 1664042X NLM ISO Abbreviation: Front Physiol Subsets: PubMed not MEDLINE
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  Data: Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis.
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Finnish Cardiovascular Research Center - Tampere, Department of Cardio-Thoracic Surgery, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Heart Center, Department of Thoracic Surgery, Tampere University Hospital, Tampere, Finland.<br /><searchLink fieldCode="AU" term="%22Srinivasan+S%22">Srinivasan S</searchLink>; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mordi+IR%22">Mordi IR</searchLink>; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Trompet+S%22">Trompet S</searchLink>; Department of Internal Medicine, Leiden University Medical Center, Leiden, Netherlands.; Section of Gerontology and Geriatrics, and Department of Cardiology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kraaijeveld+A%22">Kraaijeveld A</searchLink>; 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Finnish Cardiovascular Research Center - Tampere, Department of Clinical Physiology, Faculty of Medicine and Health Technology, Department of Clinical Physiology, Tampere University, Tampere, Finland.; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Lehtimäki+T%22">Lehtimäki T</searchLink>; Department of Clinical Chemistry, Fimlab Laboratories Ltd., Tampere, Finland.; Finnish Cardiovascular Research Center - Tampere, Department of Clinical Physiology, Faculty of Medicine and Health Technology, Department of Clinical Physiology, Tampere University, Tampere, Finland.<br /><searchLink fieldCode="AU" term="%22Lang+CC%22">Lang CC</searchLink>; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Burkhardt+R%22">Burkhardt R</searchLink>; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany.; 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    IsPartOfRelationships:
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          Dates:
            – D: 23
              M: 06
              Text: 2022 Jun 23
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-print
              Value: 1664-042X
          Numbering:
            – Type: volume
              Value: 13
          Titles:
            – TitleFull: Frontiers in physiology
              Type: main
ResultId 1