Neoadjuvant FOLFOXIRI prior to chemoradiotherapy for high-risk ("ugly") locally advanced rectal cancer: study protocol of a single-arm, multicentre, open-label, phase II trial (MEND-IT).
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| Title: | Neoadjuvant FOLFOXIRI prior to chemoradiotherapy for high-risk ("ugly") locally advanced rectal cancer: study protocol of a single-arm, multicentre, open-label, phase II trial (MEND-IT). |
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| Authors: | van den Berg K; Department of Medical Oncology, Catharina Hospital, Eindhoven, the Netherlands.; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands., Schaap DP; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands., Voogt ELK; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands., Buffart TE; Department of Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Department of Medical Oncology, Amsterdam University Medical Centres, Amsterdam, the Netherlands., Verheul HMW; Department of Medical Oncology, Radboud University Medical Centre, Nijmegen, the Netherlands., de Groot JWB; Department of Medical Oncology, Isala Oncology Centre, Zwolle, the Netherlands., Verhoef C; Department of Surgical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Melenhorst J; Department of Surgery, Maastricht University Medical Centre, Maastricht, the Netherlands., Roodhart JML; Department of Medical Oncology, University Medical Centre Utrecht, Utrecht, the Netherlands., de Wilt JHW; Department of Surgery, Radboud University Medical Centre, Nijmegen, the Netherlands., van Westreenen HL; Department of Surgery, Isala, Zwolle, the Netherlands., Aalbers AGJ; Department of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands., van 't Veer M; Department of Research and Education, Catharina Hospital, Eindhoven, the Netherlands., Marijnen CAM; Department of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Department of Radiation Oncology, Leiden University Medical Center, Leiden, the Netherlands., Vincent J; Department of Medical Oncology, Elkerliek Hospital, Helmond, the Netherlands., Simkens LHJ; Department of Medical Oncology, Maxima Medical Centre, Veldhoven, the Netherlands., Peters NAJB; Department of Medical Oncology, St. Jans Hospital, Weert, the Netherlands., Berbée M; Department of Radiation Oncology (MAASTRO), GROW School for Oncology and Reproduction, Maastricht University Medical Centre+, Maastricht, the Netherlands., Werter IM; Department of Medical Oncology, Rijnstate Hospital, Arnhem, the Netherlands., Snaebjornsson P; Department of Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Peulen HMU; Department of Radiation Oncology, Catharina Hospital, Eindhoven, the Netherlands., van Lijnschoten IG; Department of Pathology, PAMM Laboratory for Pathology and Medical Microbiology, Eindhoven, the Netherlands., Roef MJ; Department of Nuclear Medicine, Catharina Hospital, Eindhoven, the Netherlands., Nieuwenhuijzen GAP; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands., Bloemen JG; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands., Willems JMWE; Department of Medical Oncology, Anna Hospital, Geldrop, the Netherlands., Creemers GJM; Department of Medical Oncology, Catharina Hospital, Eindhoven, the Netherlands., Nederend J; Department of Radiology, Catharina Hospital, Eindhoven, the Netherlands., Rutten HJT; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.; GROW School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands., Burger JWA; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands. pim.burger@catharinaziekenhuis.nl. |
| Source: | BMC cancer [BMC Cancer] 2022 Sep 06; Vol. 22 (1), pp. 957. Date of Electronic Publication: 2022 Sep 06. |
| Publication Type: | Clinical Trial Protocol; Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 36068495 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Neoadjuvant FOLFOXIRI prior to chemoradiotherapy for high-risk ("ugly") locally advanced rectal cancer: study protocol of a single-arm, multicentre, open-label, phase II trial (MEND-IT). – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22van+den+Berg+K%22">van den Berg K</searchLink>; Department of Medical Oncology, Catharina Hospital, Eindhoven, the Netherlands.; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Schaap+DP%22">Schaap DP</searchLink>; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Voogt+ELK%22">Voogt ELK</searchLink>; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Buffart+TE%22">Buffart TE</searchLink>; Department of Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Department of Medical Oncology, Amsterdam University Medical Centres, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Verheul+HMW%22">Verheul HMW</searchLink>; Department of Medical Oncology, Radboud University Medical Centre, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Groot+JWB%22">de Groot JWB</searchLink>; Department of Medical Oncology, Isala Oncology Centre, Zwolle, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Verhoef+C%22">Verhoef C</searchLink>; Department of Surgical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Melenhorst+J%22">Melenhorst J</searchLink>; Department of Surgery, Maastricht University Medical Centre, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Roodhart+JML%22">Roodhart JML</searchLink>; Department of Medical Oncology, University Medical Centre Utrecht, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Wilt+JHW%22">de Wilt JHW</searchLink>; Department of Surgery, Radboud University Medical Centre, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Westreenen+HL%22">van Westreenen HL</searchLink>; Department of Surgery, Isala, Zwolle, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Aalbers+AGJ%22">Aalbers AGJ</searchLink>; Department of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+'t+Veer+M%22">van 't Veer M</searchLink>; Department of Research and Education, Catharina Hospital, Eindhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Marijnen+CAM%22">Marijnen CAM</searchLink>; Department of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Department of Radiation Oncology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Vincent+J%22">Vincent J</searchLink>; Department of Medical Oncology, Elkerliek Hospital, Helmond, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Simkens+LHJ%22">Simkens LHJ</searchLink>; Department of Medical Oncology, Maxima Medical Centre, Veldhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Peters+NAJB%22">Peters NAJB</searchLink>; Department of Medical Oncology, St. Jans Hospital, Weert, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Berbée+M%22">Berbée M</searchLink>; Department of Radiation Oncology (MAASTRO), GROW School for Oncology and Reproduction, Maastricht University Medical Centre+, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Werter+IM%22">Werter IM</searchLink>; Department of Medical Oncology, Rijnstate Hospital, Arnhem, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Snaebjornsson+P%22">Snaebjornsson P</searchLink>; Department of Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Peulen+HMU%22">Peulen HMU</searchLink>; Department of Radiation Oncology, Catharina Hospital, Eindhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Lijnschoten+IG%22">van Lijnschoten IG</searchLink>; Department of Pathology, PAMM Laboratory for Pathology and Medical Microbiology, Eindhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Roef+MJ%22">Roef MJ</searchLink>; Department of Nuclear Medicine, Catharina Hospital, Eindhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Nieuwenhuijzen+GAP%22">Nieuwenhuijzen GAP</searchLink>; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bloemen+JG%22">Bloemen JG</searchLink>; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Willems+JMWE%22">Willems JMWE</searchLink>; Department of Medical Oncology, Anna Hospital, Geldrop, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Creemers+GJM%22">Creemers GJM</searchLink>; Department of Medical Oncology, Catharina Hospital, Eindhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Nederend+J%22">Nederend J</searchLink>; Department of Radiology, Catharina Hospital, Eindhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Rutten+HJT%22">Rutten HJT</searchLink>; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.; GROW School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Burger+JWA%22">Burger JWA</searchLink>; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands. pim.burger@catharinaziekenhuis.nl. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22100967800%22">BMC cancer</searchLink> [BMC Cancer] 2022 Sep 06; Vol. 22 (1), pp. 957. <i>Date of Electronic Publication: </i>2022 Sep 06. – Name: TypePub Label: Publication Type Group: TypPub Data: Clinical Trial Protocol; Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100967800 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2407 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712407%22">14712407 </searchLink><i>NLM ISO Abbreviation: </i>BMC Cancer <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=36068495 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s12885-022-09947-w Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 957 Titles: – TitleFull: Neoadjuvant FOLFOXIRI prior to chemoradiotherapy for high-risk ("ugly") locally advanced rectal cancer: study protocol of a single-arm, multicentre, open-label, phase II trial (MEND-IT). Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: van den Berg K – PersonEntity: Name: NameFull: Schaap DP – PersonEntity: Name: NameFull: Voogt ELK – PersonEntity: Name: NameFull: Buffart TE – PersonEntity: Name: NameFull: Verheul HMW – PersonEntity: Name: NameFull: de Groot JWB – PersonEntity: Name: NameFull: Verhoef C – PersonEntity: Name: NameFull: Melenhorst J – PersonEntity: Name: NameFull: Roodhart JML – PersonEntity: Name: NameFull: de Wilt JHW – PersonEntity: Name: NameFull: van Westreenen HL – PersonEntity: Name: NameFull: Aalbers AGJ – PersonEntity: Name: NameFull: van 't Veer M – PersonEntity: Name: NameFull: Marijnen CAM – PersonEntity: Name: NameFull: Vincent J – PersonEntity: Name: NameFull: Simkens LHJ – PersonEntity: Name: NameFull: Peters NAJB – PersonEntity: Name: NameFull: Berbée M – PersonEntity: Name: NameFull: Werter IM – PersonEntity: Name: NameFull: Snaebjornsson P – PersonEntity: Name: NameFull: Peulen HMU – PersonEntity: Name: NameFull: van Lijnschoten IG – PersonEntity: Name: NameFull: Roef MJ – PersonEntity: Name: NameFull: Nieuwenhuijzen GAP – PersonEntity: Name: NameFull: Bloemen JG – PersonEntity: Name: NameFull: Willems JMWE – PersonEntity: Name: NameFull: Creemers GJM – PersonEntity: Name: NameFull: Nederend J – PersonEntity: Name: NameFull: Rutten HJT – PersonEntity: Name: NameFull: Burger JWA IsPartOfRelationships: – BibEntity: Dates: – D: 06 M: 09 Text: 2022 Sep 06 Type: published Y: 2022 Identifiers: – Type: issn-electronic Value: 1471-2407 Numbering: – Type: volume Value: 22 – Type: issue Value: 1 Titles: – TitleFull: BMC cancer Type: main |
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