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A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections.

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Title: A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections.
Authors: Blaskovich MAT; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Hansford KA; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Butler MS; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Ramu S; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Kavanagh AM; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Jarrad AM; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Prasetyoputri A; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Pitt ME; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Huang JX; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Lindahl F; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Ziora ZM; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Bradford T; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Muldoon C; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Rajaratnam P; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Pelingon R; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Edwards DJ; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Zhang B; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Amado M; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Elliott AG; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Zuegg J; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Coin L; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Woischnig AK; University and University Hospital of Basel, Division of Infectious Diseases and Infection Biology Laboratory Department of Biomedicine, Hebelstrasse 20, CH-4031 Basel, Switzerland., Khanna N; University and University Hospital of Basel, Division of Infectious Diseases and Infection Biology Laboratory Department of Biomedicine, Hebelstrasse 20, CH-4031 Basel, Switzerland., Breidenstein E; Summit Therapeutics, The Works, Unity Campus, Cambridgeshire, CB22 3FT, UK., Stincone A; Summit Therapeutics, The Works, Unity Campus, Cambridgeshire, CB22 3FT, UK., Mason C; Summit Therapeutics, The Works, Unity Campus, Cambridgeshire, CB22 3FT, UK., Khan N; Summit Therapeutics, The Works, Unity Campus, Cambridgeshire, CB22 3FT, UK., Cho HK; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Karau MJ; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Greenwood-Quaintance KE; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Patel R; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.; Division of Public Health, Infectious Diseases and Occupational Medicine, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA., Wootton M; Specialist Antimicrobial Chemotherapy Unit Public Health Wales, University Hospital of Wales, Heath Park, Cardiff CF14 4XW, Wales., James ML; Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia., Hutton ML; Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia., Lyras D; Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia., Ogunniyi AD; Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, South Australia 5371, Australia., Mahdi LK; Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, South Australia 5371, Australia., Trott DJ; Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, South Australia 5371, Australia., Wu X; Antimicrobial Discovery Center, Department of Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA., Niles S; Antimicrobial Discovery Center, Department of Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA., Lewis K; Antimicrobial Discovery Center, Department of Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA., Smith JR; Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA., Barber KE; Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA., Yim J; Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA., Rice SA; Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA., Rybak MJ; Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.; School of Medicine, Wayne State University, Detroit, MI 48201, USA., Ishmael CR; Department of Orthopaedic Surgery, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA., Hori KR; Department of Orthopaedic Surgery, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA., Bernthal NM; Department of Orthopaedic Surgery, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA., Francis KP; Department of Orthopaedic Surgery, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.; PerkinElmer, 68 Elm Street, Hopkinton, MA 01748, USA., Roberts JA; University of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Queensland 4029, Australia.; Departments of Pharmacy and Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Queensland 4029, Australia.; Division of Anaesthesiology Critical Care Emergency and Pain Medicine, Nîmes University Hospital, University of Montpellier, 30029 Nîmes, France., Paterson DL; University of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Queensland 4029, Australia., Cooper MA; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Source: Science translational medicine [Sci Transl Med] 2022 Sep 14; Vol. 14 (662), pp. eabj2381. Date of Electronic Publication: 2022 Sep 14.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections.
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Blaskovich+MAT%22">Blaskovich MAT</searchLink>; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Hansford+KA%22">Hansford KA</searchLink>; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Butler+MS%22">Butler MS</searchLink>; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Ramu+S%22">Ramu S</searchLink>; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Kavanagh+AM%22">Kavanagh AM</searchLink>; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Jarrad+AM%22">Jarrad AM</searchLink>; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Prasetyoputri+A%22">Prasetyoputri A</searchLink>; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Pitt+ME%22">Pitt ME</searchLink>; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Huang+JX%22">Huang JX</searchLink>; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Lindahl+F%22">Lindahl F</searchLink>; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Ziora+ZM%22">Ziora ZM</searchLink>; 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Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Zhang+B%22">Zhang B</searchLink>; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Amado+M%22">Amado M</searchLink>; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Elliott+AG%22">Elliott AG</searchLink>; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Zuegg+J%22">Zuegg J</searchLink>; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Coin+L%22">Coin L</searchLink>; 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Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, South Australia 5371, Australia.<br /><searchLink fieldCode="AU" term="%22Mahdi+LK%22">Mahdi LK</searchLink>; Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, South Australia 5371, Australia.<br /><searchLink fieldCode="AU" term="%22Trott+DJ%22">Trott DJ</searchLink>; Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, South Australia 5371, Australia.<br /><searchLink fieldCode="AU" term="%22Wu+X%22">Wu X</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Niles+S%22">Niles S</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+K%22">Lewis K</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Smith+JR%22">Smith JR</searchLink>; Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.<br /><searchLink fieldCode="AU" term="%22Barber+KE%22">Barber KE</searchLink>; Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.<br /><searchLink fieldCode="AU" term="%22Yim+J%22">Yim J</searchLink>; Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.<br /><searchLink fieldCode="AU" term="%22Rice+SA%22">Rice SA</searchLink>; Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.<br /><searchLink fieldCode="AU" term="%22Rybak+MJ%22">Rybak MJ</searchLink>; Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.; School of Medicine, Wayne State University, Detroit, MI 48201, USA.<br /><searchLink fieldCode="AU" term="%22Ishmael+CR%22">Ishmael CR</searchLink>; Department of Orthopaedic Surgery, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Hori+KR%22">Hori KR</searchLink>; Department of Orthopaedic Surgery, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Bernthal+NM%22">Bernthal NM</searchLink>; Department of Orthopaedic Surgery, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Francis+KP%22">Francis KP</searchLink>; Department of Orthopaedic Surgery, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.; PerkinElmer, 68 Elm Street, Hopkinton, MA 01748, USA.<br /><searchLink fieldCode="AU" term="%22Roberts+JA%22">Roberts JA</searchLink>; University of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Queensland 4029, Australia.; Departments of Pharmacy and Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Queensland 4029, Australia.; Division of Anaesthesiology Critical Care Emergency and Pain Medicine, Nîmes University Hospital, University of Montpellier, 30029 Nîmes, France.<br /><searchLink fieldCode="AU" term="%22Paterson+DL%22">Paterson DL</searchLink>; University of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Queensland 4029, Australia.<br /><searchLink fieldCode="AU" term="%22Cooper+MA%22">Cooper MA</searchLink>; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.
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          Name:
            NameFull: Hori KR
      – PersonEntity:
          Name:
            NameFull: Bernthal NM
      – PersonEntity:
          Name:
            NameFull: Francis KP
      – PersonEntity:
          Name:
            NameFull: Roberts JA
      – PersonEntity:
          Name:
            NameFull: Paterson DL
      – PersonEntity:
          Name:
            NameFull: Cooper MA
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 14
              M: 09
              Text: 2022 Sep 14
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-electronic
              Value: 1946-6242
          Numbering:
            – Type: volume
              Value: 14
            – Type: issue
              Value: 662
          Titles:
            – TitleFull: Science translational medicine
              Type: main
ResultId 1