Computational identification of a systemic antibiotic for gram-negative bacteria.

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Title: Computational identification of a systemic antibiotic for gram-negative bacteria.
Authors: Miller RD; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA., Iinishi A; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA., Modaresi SM; Biozentrum, University of Basel, Basel, Switzerland., Yoo BK; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA., Curtis TD; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA., Lariviere PJ; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA., Liang L; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA., Son S; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA., Nicolau S; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA., Bargabos R; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA., Morrissette M; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA., Gates MF; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA., Pitt N; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA., Jakob RP; Biozentrum, University of Basel, Basel, Switzerland., Rath P; Biozentrum, University of Basel, Basel, Switzerland., Maier T; Biozentrum, University of Basel, Basel, Switzerland., Malyutin AG; Beckman Institute, California Institute of Technology, Pasadena, CA, USA., Kaiser JT; Beckman Institute, California Institute of Technology, Pasadena, CA, USA., Niles S; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA., Karavas B; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA., Ghiglieri M; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA., Bowman SEJ; National Crystallization Center, Hauptman-Woodward Medical Research Institute, Buffalo, NY, USA., Rees DC; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA.; Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA, USA., Hiller S; Biozentrum, University of Basel, Basel, Switzerland. sebastian.hiller@unibas.ch., Lewis K; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA. k.lewis@northeastern.edu.
Source: Nature microbiology [Nat Microbiol] 2022 Oct; Vol. 7 (10), pp. 1661-1672. Date of Electronic Publication: 2022 Sep 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101674869 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2058-5276 (Electronic) Linking ISSN: 20585276 NLM ISO Abbreviation: Nat Microbiol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Miller+RD%22">Miller RD</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Iinishi+A%22">Iinishi A</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Modaresi+SM%22">Modaresi SM</searchLink>; Biozentrum, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Yoo+BK%22">Yoo BK</searchLink>; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA.<br /><searchLink fieldCode="AU" term="%22Curtis+TD%22">Curtis TD</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lariviere+PJ%22">Lariviere PJ</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Liang+L%22">Liang L</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Son+S%22">Son S</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nicolau+S%22">Nicolau S</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bargabos+R%22">Bargabos R</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Morrissette+M%22">Morrissette M</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gates+MF%22">Gates MF</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Pitt+N%22">Pitt N</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jakob+RP%22">Jakob RP</searchLink>; Biozentrum, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rath+P%22">Rath P</searchLink>; Biozentrum, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Maier+T%22">Maier T</searchLink>; Biozentrum, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Malyutin+AG%22">Malyutin AG</searchLink>; Beckman Institute, California Institute of Technology, Pasadena, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kaiser+JT%22">Kaiser JT</searchLink>; Beckman Institute, California Institute of Technology, Pasadena, CA, USA.<br /><searchLink fieldCode="AU" term="%22Niles+S%22">Niles S</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Karavas+B%22">Karavas B</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ghiglieri+M%22">Ghiglieri M</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bowman+SEJ%22">Bowman SEJ</searchLink>; National Crystallization Center, Hauptman-Woodward Medical Research Institute, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Rees+DC%22">Rees DC</searchLink>; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA.; Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hiller+S%22">Hiller S</searchLink>; Biozentrum, University of Basel, Basel, Switzerland. sebastian.hiller@unibas.ch.<br /><searchLink fieldCode="AU" term="%22Lewis+K%22">Lewis K</searchLink>; Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA, USA. k.lewis@northeastern.edu.
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  Data: <searchLink fieldCode="JN" term="%22101674869%22">Nature microbiology</searchLink> [Nat Microbiol] 2022 Oct; Vol. 7 (10), pp. 1661-1672. <i>Date of Electronic Publication: </i>2022 Sep 26.
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