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Genetically defined individual reference ranges for tryptase limit unnecessary procedures and unmask myeloid neoplasms.

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Title: Genetically defined individual reference ranges for tryptase limit unnecessary procedures and unmask myeloid neoplasms.
Authors: Chovanec J; Translational Allergic Immunopathology Unit, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD., Tunc I; Bioinformatics and Computational Biology Core, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD., Hughes J; Foundation Medicine, Cambridge, MA., Halstead J; Birmingham Women's and Children's NHS Foundation Trust, Birmingham, United Kingdom., Mateja A; Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD., Liu Y; Translational Allergic Immunopathology Unit, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD., O'Connell MP; Translational Allergic Immunopathology Unit, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD., Kim J; Translational Allergic Immunopathology Unit, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD., Park YH; Translational Allergic Immunopathology Unit, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD., Wang Q; Bioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology, NIAID, NIH, Bethesda, MD., Le Q; Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA., Pirooznia M; Bioinformatics and Computational Biology Core, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD., Trivedi NN; Cardiovascular Research Institute and Department of Medicine, University of California San Francisco, San Francisco, CA.; Veterans Affairs Medical Center, San Francisco, CA., Bai Y; Mast Cell Biology Section, Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD., Yin Y; Mast Cell Biology Section, Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD., Hsu AP; Immunopathogenesis Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD., McElwee J; Nimbus Therapeutics, Cambridge, MA., Lassiter S; Clinical Research Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD., Nelson C; Translational Allergic Immunopathology Unit, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD., Bandoh J; Translational Allergic Immunopathology Unit, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD., DiMaggio T; Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD., Šelb J; University Clinic of Respiratory and Allergic Diseases Golnik, Golnik, Slovenia., Rijavec M; University Clinic of Respiratory and Allergic Diseases Golnik, Golnik, Slovenia., Carter MC; Mast Cell Biology Section, Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD., Komarow HD; Mast Cell Biology Section, Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD., Sabato V; Department of Immunology, Allergology, and Rheumatology, Infla-Med Centre of Excellence, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium., Steinberg J; Division of Allergy and Clinical Immunology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI., Hafer KM; Department of Medicine, Stanford University, Stanford, CA., Feuille E; Division of Allergy and Clinical Immunology, Department of Pediatrics, Weill Cornell Medical College, Cornell University, New York, NY., Hourigan CS; Myeloid Malignancies Section, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD., Lack J; NIAID Collaborative Bioinformatics Resource, NIAID, NIH, Bethesda, MD., Khoury P; Human Eosinophil Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD., Maric I; Hematology Service, Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, MD., Zanotti R; Department of Medicine, Section of Hematology, Verona University Hospital, Verona, Italy., Bonadonna P; Allergy Unit, Verona University Hospital, Verona, Italy., Schwartz LB; Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA., Milner JD; Division of Allergy, Immunology and Rheumatology, Columbia University, New York, NY., Glover SC; Division of Digestive Diseases, Department of Medicine, University of Mississippi Medical Center, Jackson, MS., Ebo DG; Department of Immunology, Allergology, and Rheumatology, Infla-Med Centre of Excellence, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium., Korošec P; University Clinic of Respiratory and Allergic Diseases Golnik, Golnik, Slovenia., Caughey GH; Cardiovascular Research Institute and Department of Medicine, University of California San Francisco, San Francisco, CA.; Veterans Affairs Medical Center, San Francisco, CA., Brittain EH; Biostatistics Research Branch, NIAID, NIH, Bethesda, MD., Busby B; National Library of Medicine, National Center for Biotechnology Information, NIH, Bethesda, MD., Metcalfe DD; Mast Cell Biology Section, Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD., Lyons JJ; Translational Allergic Immunopathology Unit, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD.
Source: Blood advances [Blood Adv] 2023 May 09; Vol. 7 (9), pp. 1796-1810.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genetically defined individual reference ranges for tryptase limit unnecessary procedures and unmask myeloid neoplasms.
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  Data: <searchLink fieldCode="AU" term="%22Chovanec+J%22">Chovanec J</searchLink>; Translational Allergic Immunopathology Unit, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Tunc+I%22">Tunc I</searchLink>; Bioinformatics and Computational Biology Core, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Hughes+J%22">Hughes J</searchLink>; Foundation Medicine, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Halstead+J%22">Halstead J</searchLink>; Birmingham Women's and Children's NHS Foundation Trust, Birmingham, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mateja+A%22">Mateja A</searchLink>; Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Translational Allergic Immunopathology Unit, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22O'Connell+MP%22">O'Connell MP</searchLink>; Translational Allergic Immunopathology Unit, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Translational Allergic Immunopathology Unit, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Park+YH%22">Park YH</searchLink>; Translational Allergic Immunopathology Unit, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Bioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology, NIAID, NIH, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Le+Q%22">Le Q</searchLink>; Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA.<br /><searchLink fieldCode="AU" term="%22Pirooznia+M%22">Pirooznia M</searchLink>; Bioinformatics and Computational Biology Core, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Trivedi+NN%22">Trivedi NN</searchLink>; Cardiovascular Research Institute and Department of Medicine, University of California San Francisco, San Francisco, CA.; Veterans Affairs Medical Center, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Bai+Y%22">Bai Y</searchLink>; Mast Cell Biology Section, Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Yin+Y%22">Yin Y</searchLink>; Mast Cell Biology Section, Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Hsu+AP%22">Hsu AP</searchLink>; Immunopathogenesis Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22McElwee+J%22">McElwee J</searchLink>; Nimbus Therapeutics, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Lassiter+S%22">Lassiter S</searchLink>; Clinical Research Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD.<br /><searchLink fieldCode="AU" term="%22Nelson+C%22">Nelson C</searchLink>; Translational Allergic Immunopathology Unit, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Bandoh+J%22">Bandoh J</searchLink>; Translational Allergic Immunopathology Unit, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22DiMaggio+T%22">DiMaggio T</searchLink>; Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Šelb+J%22">Šelb J</searchLink>; University Clinic of Respiratory and Allergic Diseases Golnik, Golnik, Slovenia.<br /><searchLink fieldCode="AU" term="%22Rijavec+M%22">Rijavec M</searchLink>; University Clinic of Respiratory and Allergic Diseases Golnik, Golnik, Slovenia.<br /><searchLink fieldCode="AU" term="%22Carter+MC%22">Carter MC</searchLink>; Mast Cell Biology Section, Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Komarow+HD%22">Komarow HD</searchLink>; Mast Cell Biology Section, Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Sabato+V%22">Sabato V</searchLink>; Department of Immunology, Allergology, and Rheumatology, Infla-Med Centre of Excellence, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Steinberg+J%22">Steinberg J</searchLink>; Division of Allergy and Clinical Immunology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.<br /><searchLink fieldCode="AU" term="%22Hafer+KM%22">Hafer KM</searchLink>; Department of Medicine, Stanford University, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Feuille+E%22">Feuille E</searchLink>; Division of Allergy and Clinical Immunology, Department of Pediatrics, Weill Cornell Medical College, Cornell University, New York, NY.<br /><searchLink fieldCode="AU" term="%22Hourigan+CS%22">Hourigan CS</searchLink>; Myeloid Malignancies Section, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Lack+J%22">Lack J</searchLink>; NIAID Collaborative Bioinformatics Resource, NIAID, NIH, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Khoury+P%22">Khoury P</searchLink>; Human Eosinophil Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Maric+I%22">Maric I</searchLink>; Hematology Service, Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Zanotti+R%22">Zanotti R</searchLink>; Department of Medicine, Section of Hematology, Verona University Hospital, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Bonadonna+P%22">Bonadonna P</searchLink>; Allergy Unit, Verona University Hospital, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Schwartz+LB%22">Schwartz LB</searchLink>; Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA.<br /><searchLink fieldCode="AU" term="%22Milner+JD%22">Milner JD</searchLink>; Division of Allergy, Immunology and Rheumatology, Columbia University, New York, NY.<br /><searchLink fieldCode="AU" term="%22Glover+SC%22">Glover SC</searchLink>; Division of Digestive Diseases, Department of Medicine, University of Mississippi Medical Center, Jackson, MS.<br /><searchLink fieldCode="AU" term="%22Ebo+DG%22">Ebo DG</searchLink>; Department of Immunology, Allergology, and Rheumatology, Infla-Med Centre of Excellence, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Korošec+P%22">Korošec P</searchLink>; 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