Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma.
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| Title: | Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma. |
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| Authors: | Topham JT; Pancreas Centre BC, Vancouver, BC, Canada., Tsang ES; Division of Medical Oncology, BC Cancer, Vancouver, BC, Canada., Karasinska JM; Pancreas Centre BC, Vancouver, BC, Canada., Metcalfe A; Pancreas Centre BC, Vancouver, BC, Canada., Ali H; Pancreas Centre BC, Vancouver, BC, Canada., Kalloger SE; Pancreas Centre BC, Vancouver, BC, Canada.; Department of Pathology and Laboratory Medicine, UBC, Vancouver, BC, Canada., Csizmok V; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada., Williamson LM; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada., Titmuss E; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada., Nielsen K; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada., Negri GL; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada., Spencer Miko SE; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada., Jang GH; Ontario Institute for Cancer Research, Toronto, ON, Canada., Denroche RE; Ontario Institute for Cancer Research, Toronto, ON, Canada., Wong HL; Division of Medical Oncology, BC Cancer, Vancouver, BC, Canada., O'Kane GM; Ontario Institute for Cancer Research, Toronto, ON, Canada., Moore RA; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada., Mungall AJ; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada., Loree JM; Division of Medical Oncology, BC Cancer, Vancouver, BC, Canada., Notta F; Ontario Institute for Cancer Research, Toronto, ON, Canada., Wilson JM; Ontario Institute for Cancer Research, Toronto, ON, Canada., Bathe OF; Departments of Surgery and Oncology, Cummings School of Medicine, University of Calgary, Calgary, AB, Canada., Tang PA; Departments of Surgery and Oncology, Cummings School of Medicine, University of Calgary, Calgary, AB, Canada., Goodwin R; The Ottawa Hospital Cancer Centre, Ottawa Hospital Research Institute, Ottawa, ON, Canada., Morin GB; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Knox JJ; University Health Network, University of Toronto, Toronto, ON, Canada., Gallinger S; Ontario Institute for Cancer Research, Toronto, ON, Canada.; University Health Network, University of Toronto, Toronto, ON, Canada., Laskin J; Division of Medical Oncology, BC Cancer, Vancouver, BC, Canada.; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada., Marra MA; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada., Jones SJM; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Schaeffer DF; Pancreas Centre BC, Vancouver, BC, Canada.; Department of Pathology and Laboratory Medicine, UBC, Vancouver, BC, Canada.; Division of Anatomic Pathology, Vancouver General Hospital, Vancouver, BC, Canada., Renouf DJ; Pancreas Centre BC, Vancouver, BC, Canada. drenouf@bccancer.bc.ca.; Division of Medical Oncology, BC Cancer, Vancouver, BC, Canada. drenouf@bccancer.bc.ca.; Department of Medicine, University of British Columbia, Vancouver, BC, Canada. drenouf@bccancer.bc.ca. |
| Source: | Nature communications [Nat Commun] 2022 Oct 08; Vol. 13 (1), pp. 5941. Date of Electronic Publication: 2022 Oct 08. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 36209277 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Topham+JT%22">Topham JT</searchLink>; Pancreas Centre BC, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Tsang+ES%22">Tsang ES</searchLink>; Division of Medical Oncology, BC Cancer, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Karasinska+JM%22">Karasinska JM</searchLink>; Pancreas Centre BC, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Metcalfe+A%22">Metcalfe A</searchLink>; Pancreas Centre BC, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Ali+H%22">Ali H</searchLink>; Pancreas Centre BC, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Kalloger+SE%22">Kalloger SE</searchLink>; Pancreas Centre BC, Vancouver, BC, Canada.; Department of Pathology and Laboratory Medicine, UBC, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Csizmok+V%22">Csizmok V</searchLink>; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Williamson+LM%22">Williamson LM</searchLink>; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Titmuss+E%22">Titmuss E</searchLink>; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Nielsen+K%22">Nielsen K</searchLink>; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Negri+GL%22">Negri GL</searchLink>; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Spencer+Miko+SE%22">Spencer Miko SE</searchLink>; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Jang+GH%22">Jang GH</searchLink>; Ontario Institute for Cancer Research, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Denroche+RE%22">Denroche RE</searchLink>; Ontario Institute for Cancer Research, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Wong+HL%22">Wong HL</searchLink>; Division of Medical Oncology, BC Cancer, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22O'Kane+GM%22">O'Kane GM</searchLink>; Ontario Institute for Cancer Research, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Moore+RA%22">Moore RA</searchLink>; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Mungall+AJ%22">Mungall AJ</searchLink>; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Loree+JM%22">Loree JM</searchLink>; Division of Medical Oncology, BC Cancer, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Notta+F%22">Notta F</searchLink>; Ontario Institute for Cancer Research, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Wilson+JM%22">Wilson JM</searchLink>; Ontario Institute for Cancer Research, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Bathe+OF%22">Bathe OF</searchLink>; Departments of Surgery and Oncology, Cummings School of Medicine, University of Calgary, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Tang+PA%22">Tang PA</searchLink>; Departments of Surgery and Oncology, Cummings School of Medicine, University of Calgary, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Goodwin+R%22">Goodwin R</searchLink>; The Ottawa Hospital Cancer Centre, Ottawa Hospital Research Institute, Ottawa, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Morin+GB%22">Morin GB</searchLink>; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Knox+JJ%22">Knox JJ</searchLink>; University Health Network, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Gallinger+S%22">Gallinger S</searchLink>; Ontario Institute for Cancer Research, Toronto, ON, Canada.; University Health Network, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Laskin+J%22">Laskin J</searchLink>; Division of Medical Oncology, BC Cancer, Vancouver, BC, Canada.; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Marra+MA%22">Marra MA</searchLink>; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Jones+SJM%22">Jones SJM</searchLink>; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Schaeffer+DF%22">Schaeffer DF</searchLink>; Pancreas Centre BC, Vancouver, BC, Canada.; Department of Pathology and Laboratory Medicine, UBC, Vancouver, BC, Canada.; Division of Anatomic Pathology, Vancouver General Hospital, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Renouf+DJ%22">Renouf DJ</searchLink>; Pancreas Centre BC, Vancouver, BC, Canada. drenouf@bccancer.bc.ca.; Division of Medical Oncology, BC Cancer, Vancouver, BC, Canada. drenouf@bccancer.bc.ca.; Department of Medicine, University of British Columbia, Vancouver, BC, Canada. drenouf@bccancer.bc.ca. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2022 Oct 08; Vol. 13 (1), pp. 5941. <i>Date of Electronic Publication: </i>2022 Oct 08. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=36209277 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41467-022-33718-7 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 5941 Titles: – TitleFull: Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Topham JT – PersonEntity: Name: NameFull: Tsang ES – PersonEntity: Name: NameFull: Karasinska JM – PersonEntity: Name: NameFull: Metcalfe A – PersonEntity: Name: NameFull: Ali H – PersonEntity: Name: NameFull: Kalloger SE – PersonEntity: Name: NameFull: Csizmok V – PersonEntity: Name: NameFull: Williamson LM – PersonEntity: Name: NameFull: Titmuss E – PersonEntity: Name: NameFull: Nielsen K – PersonEntity: Name: NameFull: Negri GL – PersonEntity: Name: NameFull: Spencer Miko SE – PersonEntity: Name: NameFull: Jang GH – PersonEntity: Name: NameFull: Denroche RE – PersonEntity: Name: NameFull: Wong HL – PersonEntity: Name: NameFull: O'Kane GM – PersonEntity: Name: NameFull: Moore RA – PersonEntity: Name: NameFull: Mungall AJ – PersonEntity: Name: NameFull: Loree JM – PersonEntity: Name: NameFull: Notta F – PersonEntity: Name: NameFull: Wilson JM – PersonEntity: Name: NameFull: Bathe OF – PersonEntity: Name: NameFull: Tang PA – PersonEntity: Name: NameFull: Goodwin R – PersonEntity: Name: NameFull: Morin GB – PersonEntity: Name: NameFull: Knox JJ – PersonEntity: Name: NameFull: Gallinger S – PersonEntity: Name: NameFull: Laskin J – PersonEntity: Name: NameFull: Marra MA – PersonEntity: Name: NameFull: Jones SJM – PersonEntity: Name: NameFull: Schaeffer DF – PersonEntity: Name: NameFull: Renouf DJ IsPartOfRelationships: – BibEntity: Dates: – D: 08 M: 10 Text: 2022 Oct 08 Type: published Y: 2022 Identifiers: – Type: issn-electronic Value: 2041-1723 Numbering: – Type: volume Value: 13 – Type: issue Value: 1 Titles: – TitleFull: Nature communications Type: main |
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