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JAK2V617F mutation drives vascular resident macrophages toward a pathogenic phenotype and promotes dissecting aortic aneurysm.

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Title: JAK2V617F mutation drives vascular resident macrophages toward a pathogenic phenotype and promotes dissecting aortic aneurysm.
Authors: Al-Rifai R; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France., Vandestienne M; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France., Lavillegrand JR; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France., Mirault T; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.; Service de médecine vasculaire, Hopital Européen G. Pompidou, Paris, France., Cornebise J; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France., Poisson J; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.; Service de gériatrie, Hopital Européen G. Pompidou, Paris, France.; Centre de recherche sur l'inflammation, Inserm, Paris, France., Laurans L; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France., Esposito B; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France., James C; Université de Bordeaux, UMR1034, Inserm, Biology of Cardiovascular Diseases, CHU de Bordeaux, Laboratoire d'Hématologie, Pessac, France., Mansier O; Université de Bordeaux, UMR1034, Inserm, Biology of Cardiovascular Diseases, CHU de Bordeaux, Laboratoire d'Hématologie, Pessac, France., Hirsch P; Laboratoire d'Hématologie, Hôpital Saint-Antoine, AP-HP, Paris, France., Favale F; Laboratoire d'Hématologie, Hôpital Saint-Antoine, AP-HP, Paris, France., Braik R; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France., Knosp C; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France., Vilar J; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France., Rizzo G; Institute of Experimental Biomedicine, University Hospital Wuerzburg, Würzburg, Germany., Zernecke A; Institute of Experimental Biomedicine, University Hospital Wuerzburg, Würzburg, Germany., Saliba AE; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz-Center for Infection Research (HZI), Würzburg, Germany., Tedgui A; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France., Lacroix M; Service de radiologie, Hôpital Saint-Antoine, AP-HP, Paris, France., Arrive L; Service de radiologie, Hôpital Saint-Antoine, AP-HP, Paris, France., Mallat Z; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France., Taleb S; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France., Diedisheim M; GlandOmics, 41700 Cheverny, & Department of Diabetology, AP-HP, Hôpital Cochin, Paris, France., Cochain C; Institute of Experimental Biomedicine, University Hospital Wuerzburg, Würzburg, Germany., Rautou PE; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.; Centre de recherche sur l'inflammation, Inserm, Paris, France.; AP-HP, Hôpital Beaujon, Service d'Hépatologie, DMU DIGEST, Centre de Référence des Maladies Vasculaires du Foie, FILFOIE, ERN RARE-LIVER, Clichy, France., Ait-Oufella H; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France. hafid.aitoufella@inserm.fr.; Medical Intensive Care Unit, Hôpital Saint-Antoine, AP-HP, Sorbonne Université, Paris, France. hafid.aitoufella@inserm.fr.
Source: Nature communications [Nat Commun] 2022 Nov 03; Vol. 13 (1), pp. 6592. Date of Electronic Publication: 2022 Nov 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: JAK2V617F mutation drives vascular resident macrophages toward a pathogenic phenotype and promotes dissecting aortic aneurysm.
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  Data: <searchLink fieldCode="AU" term="%22Al-Rifai+R%22">Al-Rifai R</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Vandestienne+M%22">Vandestienne M</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Lavillegrand+JR%22">Lavillegrand JR</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Mirault+T%22">Mirault T</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.; Service de médecine vasculaire, Hopital Européen G. Pompidou, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cornebise+J%22">Cornebise J</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Poisson+J%22">Poisson J</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.; Service de gériatrie, Hopital Européen G. Pompidou, Paris, France.; Centre de recherche sur l'inflammation, Inserm, Paris, France.<br /><searchLink fieldCode="AU" term="%22Laurans+L%22">Laurans L</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Esposito+B%22">Esposito B</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22James+C%22">James C</searchLink>; Université de Bordeaux, UMR1034, Inserm, Biology of Cardiovascular Diseases, CHU de Bordeaux, Laboratoire d'Hématologie, Pessac, France.<br /><searchLink fieldCode="AU" term="%22Mansier+O%22">Mansier O</searchLink>; Université de Bordeaux, UMR1034, Inserm, Biology of Cardiovascular Diseases, CHU de Bordeaux, Laboratoire d'Hématologie, Pessac, France.<br /><searchLink fieldCode="AU" term="%22Hirsch+P%22">Hirsch P</searchLink>; Laboratoire d'Hématologie, Hôpital Saint-Antoine, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Favale+F%22">Favale F</searchLink>; Laboratoire d'Hématologie, Hôpital Saint-Antoine, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Braik+R%22">Braik R</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Knosp+C%22">Knosp C</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Vilar+J%22">Vilar J</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Rizzo+G%22">Rizzo G</searchLink>; Institute of Experimental Biomedicine, University Hospital Wuerzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Zernecke+A%22">Zernecke A</searchLink>; Institute of Experimental Biomedicine, University Hospital Wuerzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Saliba+AE%22">Saliba AE</searchLink>; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz-Center for Infection Research (HZI), Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Tedgui+A%22">Tedgui A</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Lacroix+M%22">Lacroix M</searchLink>; Service de radiologie, Hôpital Saint-Antoine, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Arrive+L%22">Arrive L</searchLink>; Service de radiologie, Hôpital Saint-Antoine, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Mallat+Z%22">Mallat Z</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Taleb+S%22">Taleb S</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Diedisheim+M%22">Diedisheim M</searchLink>; GlandOmics, 41700 Cheverny, & Department of Diabetology, AP-HP, Hôpital Cochin, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cochain+C%22">Cochain C</searchLink>; Institute of Experimental Biomedicine, University Hospital Wuerzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Rautou+PE%22">Rautou PE</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.; Centre de recherche sur l'inflammation, Inserm, Paris, France.; AP-HP, Hôpital Beaujon, Service d'Hépatologie, DMU DIGEST, Centre de Référence des Maladies Vasculaires du Foie, FILFOIE, ERN RARE-LIVER, Clichy, France.<br /><searchLink fieldCode="AU" term="%22Ait-Oufella+H%22">Ait-Oufella H</searchLink>; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France. hafid.aitoufella@inserm.fr.; Medical Intensive Care Unit, Hôpital Saint-Antoine, AP-HP, Sorbonne Université, Paris, France. hafid.aitoufella@inserm.fr.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2022 Nov 03; Vol. 13 (1), pp. 6592. <i>Date of Electronic Publication: </i>2022 Nov 03.
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