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Genomic architecture of autism from comprehensive whole-genome sequence annotation.

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Title: Genomic architecture of autism from comprehensive whole-genome sequence annotation.
Authors: Trost B; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Thiruvahindrapuram B; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Chan AJS; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Engchuan W; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Higginbotham EJ; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Howe JL; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Loureiro LO; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Reuter MS; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; CGEn, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Roshandel D; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Whitney J; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Zarrei M; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Bookman M; Verily Life Sciences, South San Francisco, CA 94080, USA., Somerville C; Ted Rogers Centre for Heart Research, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada., Shaath R; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Abdi M; Department of Human Genetics, Sidra Medicine, Doha, Qatar; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar., Aliyev E; Department of Human Genetics, Sidra Medicine, Doha, Qatar., Patel RV; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Nalpathamkalam T; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Pellecchia G; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Hamdan O; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Kaur G; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Wang Z; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., MacDonald JR; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Wei J; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Sung WWL; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Lamoureux S; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Hoang N; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Autism Research Unit, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Genetic Counselling, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada., Selvanayagam T; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Autism Research Unit, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Genetic Counselling, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada., Deflaux N; Verily Life Sciences, South San Francisco, CA 94080, USA., Geng M; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada., Ghaffari S; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Bates J; Verily Life Sciences, South San Francisco, CA 94080, USA., Young EJ; Genome Diagnostics, Department of Paediatric Medicine, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada., Ding Q; Ted Rogers Centre for Heart Research, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada., Shum C; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., D'Abate L; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Bradley CA; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Rutherford A; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada., Aguda V; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Apresto B; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Chen N; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Desai S; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Du X; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Fong MLY; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Pullenayegum S; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Samler K; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Wang T; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Ho K; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Paton T; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Pereira SL; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Herbrick JA; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Wintle RF; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Fuerth J; DNAstack, Toronto, ON M5H 1T1, Canada., Noppornpitak J; DNAstack, Toronto, ON M5H 1T1, Canada., Ward H; DNAstack, Toronto, ON M5H 1T1, Canada., Magee P; DNAstack, Toronto, ON M5H 1T1, Canada., Al Baz A; DNAstack, Toronto, ON M5H 1T1, Canada., Kajendirarajah U; DNAstack, Toronto, ON M5H 1T1, Canada., Kapadia S; DNAstack, Toronto, ON M5H 1T1, Canada., Vlasblom J; DNAstack, Toronto, ON M5H 1T1, Canada., Valluri M; DNAstack, Toronto, ON M5H 1T1, Canada., Green J; DNAstack, Toronto, ON M5H 1T1, Canada., Seifer V; Autism Speaks, Princeton, NJ 08540, USA., Quirbach M; Autism Speaks, Princeton, NJ 08540, USA., Rennie O; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Kelley E; Department of Psychology, Queen's University, Kingston, ON K7L 3N6, Canada; Department of Psychiatry, Queen's University, Kingston, ON K7L 7X3, Canada., Masjedi N; Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA 90024, USA., Lord C; Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA 90024, USA., Szego MJ; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Family and Community Medicine, University of Toronto, Toronto, ON M5G 1V7, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5T 3M7, Canada., Zawati MH; Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada., Lang M; Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada., Strug LJ; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Statistical Sciences, University of Toronto, Toronto, ON M5S 3G3, Canada., Marshall CR; Genome Diagnostics, Department of Paediatric Medicine, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada., Costain G; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Pediatrics, University of Toronto, Toronto, ON M5G 1X8, Canada., Calli K; Department of Medical Genetics, University of British Columbia, Vancouver, BC V6H 3N1, Canada; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada., Iaboni A; Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON M4G 1R8, Canada., Yusuf A; Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada., Ambrozewicz P; Autism Research Unit, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Psychology, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada., Gallagher L; Department of Psychiatry, School of Medicine, Trinity College Dublin, Dublin 2, Ireland; Department of Psychiatry, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Child, Youth and Family Services, The Centre for Addiction and Mental Health, Toronto, ON M6J 1H4, Canada; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada., Amaral DG; MIND Institute, University of California, Davis, Sacramento, CA 95817, USA; Department of Psychiatry and Behavioral Sciences, University of California, Davis, Sacramento, CA 95817, USA., Brian J; Department of Pediatrics, University of Toronto, Toronto, ON M5G 1X8, Canada; Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON M4G 1R8, Canada., Elsabbagh M; Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada., Georgiades S; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON L8N 3K7, Canada., Messinger DS; Department of Psychology, University of Miami, Miami, FL 33124, USA., Ozonoff S; MIND Institute, University of California, Davis, Sacramento, CA 95817, USA; Department of Psychiatry and Behavioral Sciences, University of California, Davis, Sacramento, CA 95817, USA., Sebat J; Department of Psychiatry and Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Sjaarda C; Department of Psychiatry, Queen's University, Kingston, ON K7L 7X3, Canada; Queen's Genomics Lab at Ongwanada, Queen's University, Kingston, ON K7M 8A6, Canada., Smith IM; Department of Pediatrics, Dalhousie University, Halifax, NS B3H 4R2, Canada; IWK Health Centre, Halifax, NS B3K 6R8, Canada., Szatmari P; Department of Psychiatry, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada; Centre for Addiction and Mental Health, Toronto, ON M6J 1H4, Canada., Zwaigenbaum L; Department of Pediatrics, University of Alberta, Edmonton, AB T6G 1C9, Canada., Kushki A; Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON M4G 1R8, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, ON M5S 3G9, Canada., Frazier TW; Autism Speaks, Princeton, NJ 08540, USA; Department of Psychology, John Carroll University, Cleveland, OH 44118, USA., Vorstman JAS; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada., Fakhro KA; Department of Human Genetics, Sidra Medicine, Doha, Qatar; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar; Department of Genetic Medicine, Weill Cornell Medical College in Qatar, Doha, Qatar., Fernandez BA; Department of Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA; Keck School of Medicine of USC, University of Southern California, Los Angeles, CA 90033, USA., Lewis MES; Department of Medical Genetics, University of British Columbia, Vancouver, BC V6H 3N1, Canada; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada., Weksberg R; Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Pediatrics, University of Toronto, Toronto, ON M5G 1X8, Canada., Fiume M; DNAstack, Toronto, ON M5H 1T1, Canada., Yuen RKC; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada., Anagnostou E; Department of Pediatrics, University of Toronto, Toronto, ON M5G 1X8, Canada; Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON M4G 1R8, Canada., Sondheimer N; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Pediatrics, University of Toronto, Toronto, ON M5G 1X8, Canada., Glazer D; Verily Life Sciences, South San Francisco, CA 94080, USA., Hartley DM; Autism Speaks, Princeton, NJ 08540, USA., Scherer SW; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; McLaughlin Centre, Toronto, ON M5G 0A4, Canada. Electronic address: stephen.scherer@sickkids.ca.
Source: Cell [Cell] 2022 Nov 10; Vol. 185 (23), pp. 4409-4427.e18.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 36368308
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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Items – Name: Title
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  Data: Genomic architecture of autism from comprehensive whole-genome sequence annotation.
– Name: Author
  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Trost+B%22">Trost B</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Thiruvahindrapuram+B%22">Thiruvahindrapuram B</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Chan+AJS%22">Chan AJS</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Engchuan+W%22">Engchuan W</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Higginbotham+EJ%22">Higginbotham EJ</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Howe+JL%22">Howe JL</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Loureiro+LO%22">Loureiro LO</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Reuter+MS%22">Reuter MS</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; CGEn, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Roshandel+D%22">Roshandel D</searchLink>; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Whitney+J%22">Whitney J</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Zarrei+M%22">Zarrei M</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Bookman+M%22">Bookman M</searchLink>; Verily Life Sciences, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Somerville+C%22">Somerville C</searchLink>; Ted Rogers Centre for Heart Research, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.<br /><searchLink fieldCode="AU" term="%22Shaath+R%22">Shaath R</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Abdi+M%22">Abdi M</searchLink>; Department of Human Genetics, Sidra Medicine, Doha, Qatar; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.<br /><searchLink fieldCode="AU" term="%22Aliyev+E%22">Aliyev E</searchLink>; Department of Human Genetics, Sidra Medicine, Doha, Qatar.<br /><searchLink fieldCode="AU" term="%22Patel+RV%22">Patel RV</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Nalpathamkalam+T%22">Nalpathamkalam T</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Pellecchia+G%22">Pellecchia G</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Hamdan+O%22">Hamdan O</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Kaur+G%22">Kaur G</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22MacDonald+JR%22">MacDonald JR</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Wei+J%22">Wei J</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Sung+WWL%22">Sung WWL</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Lamoureux+S%22">Lamoureux S</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Hoang+N%22">Hoang N</searchLink>; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Autism Research Unit, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Genetic Counselling, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.<br /><searchLink fieldCode="AU" term="%22Selvanayagam+T%22">Selvanayagam T</searchLink>; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Autism Research Unit, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Genetic Counselling, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.<br /><searchLink fieldCode="AU" term="%22Deflaux+N%22">Deflaux N</searchLink>; Verily Life Sciences, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Geng+M%22">Geng M</searchLink>; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Ghaffari+S%22">Ghaffari S</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Bates+J%22">Bates J</searchLink>; Verily Life Sciences, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Young+EJ%22">Young EJ</searchLink>; Genome Diagnostics, Department of Paediatric Medicine, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.<br /><searchLink fieldCode="AU" term="%22Ding+Q%22">Ding Q</searchLink>; Ted Rogers Centre for Heart Research, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.<br /><searchLink fieldCode="AU" term="%22Shum+C%22">Shum C</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22D'Abate+L%22">D'Abate L</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Bradley+CA%22">Bradley CA</searchLink>; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Rutherford+A%22">Rutherford A</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Aguda+V%22">Aguda V</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Apresto+B%22">Apresto B</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Chen+N%22">Chen N</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Desai+S%22">Desai S</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Du+X%22">Du X</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Fong+MLY%22">Fong MLY</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Pullenayegum+S%22">Pullenayegum S</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Samler+K%22">Samler K</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Ho+K%22">Ho K</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Paton+T%22">Paton T</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Pereira+SL%22">Pereira SL</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Herbrick+JA%22">Herbrick JA</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Wintle+RF%22">Wintle RF</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Fuerth+J%22">Fuerth J</searchLink>; DNAstack, Toronto, ON M5H 1T1, Canada.<br /><searchLink fieldCode="AU" term="%22Noppornpitak+J%22">Noppornpitak J</searchLink>; DNAstack, Toronto, ON M5H 1T1, Canada.<br /><searchLink fieldCode="AU" term="%22Ward+H%22">Ward H</searchLink>; DNAstack, Toronto, ON M5H 1T1, Canada.<br /><searchLink fieldCode="AU" term="%22Magee+P%22">Magee P</searchLink>; DNAstack, Toronto, ON M5H 1T1, Canada.<br /><searchLink fieldCode="AU" term="%22Al+Baz+A%22">Al Baz A</searchLink>; DNAstack, Toronto, ON M5H 1T1, Canada.<br /><searchLink fieldCode="AU" term="%22Kajendirarajah+U%22">Kajendirarajah U</searchLink>; DNAstack, Toronto, ON M5H 1T1, Canada.<br /><searchLink fieldCode="AU" term="%22Kapadia+S%22">Kapadia S</searchLink>; DNAstack, Toronto, ON M5H 1T1, Canada.<br /><searchLink fieldCode="AU" term="%22Vlasblom+J%22">Vlasblom J</searchLink>; DNAstack, Toronto, ON M5H 1T1, Canada.<br /><searchLink fieldCode="AU" term="%22Valluri+M%22">Valluri M</searchLink>; DNAstack, Toronto, ON M5H 1T1, Canada.<br /><searchLink fieldCode="AU" term="%22Green+J%22">Green J</searchLink>; DNAstack, Toronto, ON M5H 1T1, Canada.<br /><searchLink fieldCode="AU" term="%22Seifer+V%22">Seifer V</searchLink>; Autism Speaks, Princeton, NJ 08540, USA.<br /><searchLink fieldCode="AU" term="%22Quirbach+M%22">Quirbach M</searchLink>; Autism Speaks, Princeton, NJ 08540, USA.<br /><searchLink fieldCode="AU" term="%22Rennie+O%22">Rennie O</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Kelley+E%22">Kelley E</searchLink>; Department of Psychology, Queen's University, Kingston, ON K7L 3N6, Canada; Department of Psychiatry, Queen's University, Kingston, ON K7L 7X3, Canada.<br /><searchLink fieldCode="AU" term="%22Masjedi+N%22">Masjedi N</searchLink>; Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA 90024, USA.<br /><searchLink fieldCode="AU" term="%22Lord+C%22">Lord C</searchLink>; Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA 90024, USA.<br /><searchLink fieldCode="AU" term="%22Szego+MJ%22">Szego MJ</searchLink>; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Family and Community Medicine, University of Toronto, Toronto, ON M5G 1V7, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5T 3M7, Canada.<br /><searchLink fieldCode="AU" term="%22Zawati+MH%22">Zawati MH</searchLink>; Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada.<br /><searchLink fieldCode="AU" term="%22Lang+M%22">Lang M</searchLink>; Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada.<br /><searchLink fieldCode="AU" term="%22Strug+LJ%22">Strug LJ</searchLink>; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Statistical Sciences, University of Toronto, Toronto, ON M5S 3G3, Canada.<br /><searchLink fieldCode="AU" term="%22Marshall+CR%22">Marshall CR</searchLink>; Genome Diagnostics, Department of Paediatric Medicine, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Costain+G%22">Costain G</searchLink>; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Pediatrics, University of Toronto, Toronto, ON M5G 1X8, Canada.<br /><searchLink fieldCode="AU" term="%22Calli+K%22">Calli K</searchLink>; Department of Medical Genetics, University of British Columbia, Vancouver, BC V6H 3N1, Canada; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.<br /><searchLink fieldCode="AU" term="%22Iaboni+A%22">Iaboni A</searchLink>; Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON M4G 1R8, Canada.<br /><searchLink fieldCode="AU" term="%22Yusuf+A%22">Yusuf A</searchLink>; Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.<br /><searchLink fieldCode="AU" term="%22Ambrozewicz+P%22">Ambrozewicz P</searchLink>; Autism Research Unit, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Psychology, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.<br /><searchLink fieldCode="AU" term="%22Gallagher+L%22">Gallagher L</searchLink>; Department of Psychiatry, School of Medicine, Trinity College Dublin, Dublin 2, Ireland; Department of Psychiatry, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Child, Youth and Family Services, The Centre for Addiction and Mental Health, Toronto, ON M6J 1H4, Canada; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.<br /><searchLink fieldCode="AU" term="%22Amaral+DG%22">Amaral DG</searchLink>; MIND Institute, University of California, Davis, Sacramento, CA 95817, USA; Department of Psychiatry and Behavioral Sciences, University of California, Davis, Sacramento, CA 95817, USA.<br /><searchLink fieldCode="AU" term="%22Brian+J%22">Brian J</searchLink>; Department of Pediatrics, University of Toronto, Toronto, ON M5G 1X8, Canada; Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON M4G 1R8, Canada.<br /><searchLink fieldCode="AU" term="%22Elsabbagh+M%22">Elsabbagh M</searchLink>; Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.<br /><searchLink fieldCode="AU" term="%22Georgiades+S%22">Georgiades S</searchLink>; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON L8N 3K7, Canada.<br /><searchLink fieldCode="AU" term="%22Messinger+DS%22">Messinger DS</searchLink>; Department of Psychology, University of Miami, Miami, FL 33124, USA.<br /><searchLink fieldCode="AU" term="%22Ozonoff+S%22">Ozonoff S</searchLink>; MIND Institute, University of California, Davis, Sacramento, CA 95817, USA; Department of Psychiatry and Behavioral Sciences, University of California, Davis, Sacramento, CA 95817, USA.<br /><searchLink fieldCode="AU" term="%22Sebat+J%22">Sebat J</searchLink>; Department of Psychiatry and Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.<br /><searchLink fieldCode="AU" term="%22Sjaarda+C%22">Sjaarda C</searchLink>; Department of Psychiatry, Queen's University, Kingston, ON K7L 7X3, Canada; Queen's Genomics Lab at Ongwanada, Queen's University, Kingston, ON K7M 8A6, Canada.<br /><searchLink fieldCode="AU" term="%22Smith+IM%22">Smith IM</searchLink>; Department of Pediatrics, Dalhousie University, Halifax, NS B3H 4R2, Canada; IWK Health Centre, Halifax, NS B3K 6R8, Canada.<br /><searchLink fieldCode="AU" term="%22Szatmari+P%22">Szatmari P</searchLink>; Department of Psychiatry, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada; Centre for Addiction and Mental Health, Toronto, ON M6J 1H4, Canada.<br /><searchLink fieldCode="AU" term="%22Zwaigenbaum+L%22">Zwaigenbaum L</searchLink>; Department of Pediatrics, University of Alberta, Edmonton, AB T6G 1C9, Canada.<br /><searchLink fieldCode="AU" term="%22Kushki+A%22">Kushki A</searchLink>; Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON M4G 1R8, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, ON M5S 3G9, Canada.<br /><searchLink fieldCode="AU" term="%22Frazier+TW%22">Frazier TW</searchLink>; Autism Speaks, Princeton, NJ 08540, USA; Department of Psychology, John Carroll University, Cleveland, OH 44118, USA.<br /><searchLink fieldCode="AU" term="%22Vorstman+JAS%22">Vorstman JAS</searchLink>; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.<br /><searchLink fieldCode="AU" term="%22Fakhro+KA%22">Fakhro KA</searchLink>; Department of Human Genetics, Sidra Medicine, Doha, Qatar; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar; Department of Genetic Medicine, Weill Cornell Medical College in Qatar, Doha, Qatar.<br /><searchLink fieldCode="AU" term="%22Fernandez+BA%22">Fernandez BA</searchLink>; Department of Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA; Keck School of Medicine of USC, University of Southern California, Los Angeles, CA 90033, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+MES%22">Lewis MES</searchLink>; Department of Medical Genetics, University of British Columbia, Vancouver, BC V6H 3N1, Canada; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.<br /><searchLink fieldCode="AU" term="%22Weksberg+R%22">Weksberg R</searchLink>; Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Pediatrics, University of Toronto, Toronto, ON M5G 1X8, Canada.<br /><searchLink fieldCode="AU" term="%22Fiume+M%22">Fiume M</searchLink>; DNAstack, Toronto, ON M5H 1T1, Canada.<br /><searchLink fieldCode="AU" term="%22Yuen+RKC%22">Yuen RKC</searchLink>; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Anagnostou+E%22">Anagnostou E</searchLink>; Department of Pediatrics, University of Toronto, Toronto, ON M5G 1X8, Canada; Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON M4G 1R8, Canada.<br /><searchLink fieldCode="AU" term="%22Sondheimer+N%22">Sondheimer N</searchLink>; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Pediatrics, University of Toronto, Toronto, ON M5G 1X8, Canada.<br /><searchLink fieldCode="AU" term="%22Glazer+D%22">Glazer D</searchLink>; Verily Life Sciences, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Hartley+DM%22">Hartley DM</searchLink>; Autism Speaks, Princeton, NJ 08540, USA.<br /><searchLink fieldCode="AU" term="%22Scherer+SW%22">Scherer SW</searchLink>; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; McLaughlin Centre, Toronto, ON M5G 0A4, Canada. Electronic address: stephen.scherer@sickkids.ca.
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  Data: <searchLink fieldCode="JN" term="%220413066%22">Cell</searchLink> [Cell] 2022 Nov 10; Vol. 185 (23), pp. 4409-4427.e18.
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  Data: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
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        Value: 10.1016/j.cell.2022.10.009
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      – TitleFull: Genomic architecture of autism from comprehensive whole-genome sequence annotation.
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          Name:
            NameFull: Brian J
      – PersonEntity:
          Name:
            NameFull: Elsabbagh M
      – PersonEntity:
          Name:
            NameFull: Georgiades S
      – PersonEntity:
          Name:
            NameFull: Messinger DS
      – PersonEntity:
          Name:
            NameFull: Ozonoff S
      – PersonEntity:
          Name:
            NameFull: Sebat J
      – PersonEntity:
          Name:
            NameFull: Sjaarda C
      – PersonEntity:
          Name:
            NameFull: Smith IM
      – PersonEntity:
          Name:
            NameFull: Szatmari P
      – PersonEntity:
          Name:
            NameFull: Zwaigenbaum L
      – PersonEntity:
          Name:
            NameFull: Kushki A
      – PersonEntity:
          Name:
            NameFull: Frazier TW
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          Name:
            NameFull: Vorstman JAS
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          Name:
            NameFull: Fakhro KA
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          Name:
            NameFull: Fernandez BA
      – PersonEntity:
          Name:
            NameFull: Lewis MES
      – PersonEntity:
          Name:
            NameFull: Weksberg R
      – PersonEntity:
          Name:
            NameFull: Fiume M
      – PersonEntity:
          Name:
            NameFull: Yuen RKC
      – PersonEntity:
          Name:
            NameFull: Anagnostou E
      – PersonEntity:
          Name:
            NameFull: Sondheimer N
      – PersonEntity:
          Name:
            NameFull: Glazer D
      – PersonEntity:
          Name:
            NameFull: Hartley DM
      – PersonEntity:
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            NameFull: Scherer SW
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 10
              M: 11
              Text: 2022 Nov 10
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-electronic
              Value: 1097-4172
          Numbering:
            – Type: volume
              Value: 185
            – Type: issue
              Value: 23
          Titles:
            – TitleFull: Cell
              Type: main
ResultId 1