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Highly potent and selective 5-lipoxygenase inhibition by new, simple heteroaryl-substituted catechols for treatment of inflammation.

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Title: Highly potent and selective 5-lipoxygenase inhibition by new, simple heteroaryl-substituted catechols for treatment of inflammation.
Authors: Krauth V; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, 07743 Jena, Germany., Bruno F; Department of Science and Technology, University of Sannio, 82100 Benevento, Italy; Advanced Medical Pharma, (AMP-BIOTEC) Healthcare Research and Innovation Center, 82030 San Salvatore Telesino, (BN), Italy., Pace S; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, 07743 Jena, Germany., Jordan PM; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, 07743 Jena, Germany., Temml V; Department of Pharmaceutical Chemistry, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria., Preziosa Romano M; Department of Science and Technology, University of Sannio, 82100 Benevento, Italy; Advanced Medical Pharma, (AMP-BIOTEC) Healthcare Research and Innovation Center, 82030 San Salvatore Telesino, (BN), Italy., Khan H; Department of Pharmacy, Faculty of Chemical and Life Sciences, Abdul Wali Khan University, Mardan 23200, Pakistan., Schuster D; Department of Pharmaceutical Chemistry, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria., Rossi A; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, I-80131 Naples, Italy., Filosa R; Department of Science and Technology, University of Sannio, 82100 Benevento, Italy; Advanced Medical Pharma, (AMP-BIOTEC) Healthcare Research and Innovation Center, 82030 San Salvatore Telesino, (BN), Italy; Istituti Clinici Scientifici Maugeri IRCCS, Cardiac Rehabilitation Unit of Telese Terme Institute, Italy. Electronic address: rfilosa@unisannio.it., Werz O; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, 07743 Jena, Germany. Electronic address: oliver.werz@uni-jena.de.
Source: Biochemical pharmacology [Biochem Pharmacol] 2023 Feb; Vol. 208, pp. 115385. Date of Electronic Publication: 2022 Dec 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Krauth+V%22">Krauth V</searchLink>; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, 07743 Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Bruno+F%22">Bruno F</searchLink>; Department of Science and Technology, University of Sannio, 82100 Benevento, Italy; Advanced Medical Pharma, (AMP-BIOTEC) Healthcare Research and Innovation Center, 82030 San Salvatore Telesino, (BN), Italy.<br /><searchLink fieldCode="AU" term="%22Pace+S%22">Pace S</searchLink>; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, 07743 Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Jordan+PM%22">Jordan PM</searchLink>; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, 07743 Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Temml+V%22">Temml V</searchLink>; Department of Pharmaceutical Chemistry, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria.<br /><searchLink fieldCode="AU" term="%22Preziosa+Romano+M%22">Preziosa Romano M</searchLink>; Department of Science and Technology, University of Sannio, 82100 Benevento, Italy; Advanced Medical Pharma, (AMP-BIOTEC) Healthcare Research and Innovation Center, 82030 San Salvatore Telesino, (BN), Italy.<br /><searchLink fieldCode="AU" term="%22Khan+H%22">Khan H</searchLink>; Department of Pharmacy, Faculty of Chemical and Life Sciences, Abdul Wali Khan University, Mardan 23200, Pakistan.<br /><searchLink fieldCode="AU" term="%22Schuster+D%22">Schuster D</searchLink>; Department of Pharmaceutical Chemistry, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria.<br /><searchLink fieldCode="AU" term="%22Rossi+A%22">Rossi A</searchLink>; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, I-80131 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Filosa+R%22">Filosa R</searchLink>; Department of Science and Technology, University of Sannio, 82100 Benevento, Italy; Advanced Medical Pharma, (AMP-BIOTEC) Healthcare Research and Innovation Center, 82030 San Salvatore Telesino, (BN), Italy; Istituti Clinici Scientifici Maugeri IRCCS, Cardiac Rehabilitation Unit of Telese Terme Institute, Italy. Electronic address: rfilosa@unisannio.it.<br /><searchLink fieldCode="AU" term="%22Werz+O%22">Werz O</searchLink>; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, 07743 Jena, Germany. Electronic address: oliver.werz@uni-jena.de.
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  Data: <searchLink fieldCode="JN" term="%220101032%22">Biochemical pharmacology</searchLink> [Biochem Pharmacol] 2023 Feb; Vol. 208, pp. 115385. <i>Date of Electronic Publication: </i>2022 Dec 17.
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