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Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children.

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Title: Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children.
Authors: Xu Q; Cell Signaling and Immunity Section, Laboratory of Immune System Biology (LISB), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Milanez-Almeida P; Center for Human Immunology, NIAID, NIH, Bethesda, MD, USA., Martins AJ; Multiscale Systems Biology Section, LISB, NIAID, NIH, Bethesda, MD, USA., Radtke AJ; Center for Advanced Tissue Imaging, LISB, NIAID, NIH, Bethesda, MD, USA., Hoehn KB; Department of Pathology, Yale School of Medicine, New Haven, CT, USA., Oguz C; NIAID Collaborative Bioinformatics Resource (NCBR), NIAID, NIH, Bethesda, MD, USA.; Axle Informatics, Bethesda, MD, USA., Chen J; Center for Human Immunology, NIAID, NIH, Bethesda, MD, USA., Liu C; Multiscale Systems Biology Section, LISB, NIAID, NIH, Bethesda, MD, USA., Tang J; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), Silver Spring, MD, USA., Grubbs G; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), Silver Spring, MD, USA., Stein S; Emerging Pathogens Section, Critical Care Medicine Department, Clinical Center (CC), NIH, Bethesda, MD, USA.; Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD, USA., Ramelli S; Emerging Pathogens Section, Critical Care Medicine Department, Clinical Center (CC), NIH, Bethesda, MD, USA., Kabat J; Center for Advanced Tissue Imaging, LISB, NIAID, NIH, Bethesda, MD, USA., Behzadpour H; Division of Pediatric Otolaryngology, Children's National Hospital, Washington, DC, USA., Karkanitsa M; Laboratory of Immuno-Engineering, National Institute of Biomedical Imaging and Bioengineering (NIBIB), NIH, Bethesda, MD, USA., Spathies J; Trans-NIH Shared Resource on Biomedical Engineering and Physical Science, NIBIB, NIH, Bethesda, MD, USA., Kalish H; Trans-NIH Shared Resource on Biomedical Engineering and Physical Science, NIBIB, NIH, Bethesda, MD, USA., Kardava L; B-cell Immunology Section, Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD, USA., Kirby M; National Human Genome Research Institute (NHGRI), NIH, Bethesda, MD, USA., Cheung F; Center for Human Immunology, NIAID, NIH, Bethesda, MD, USA., Preite S; Cell Signaling and Immunity Section, Laboratory of Immune System Biology (LISB), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Duncker PC; Cytek Biosciences, Fremont, CA, USA., Kitakule MM; Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD, USA., Romero N; Division of Otolaryngology, Department of Surgery, George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Preciado D; Division of Pediatric Otolaryngology, Children's National Hospital, Washington, DC, USA.; Division of Otolaryngology, Department of Surgery, George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Gitman L; Division of Pediatric Otolaryngology, Children's National Hospital, Washington, DC, USA.; Division of Otolaryngology, Department of Surgery, George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Koroleva G; Center for Human Immunology, NIAID, NIH, Bethesda, MD, USA., Smith G; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute (NCI), NIH, Bethesda, MD, USA., Shaffer A; Lymphoid Malignancies Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA., McBain IT; Cell Signaling and Immunity Section, Laboratory of Immune System Biology (LISB), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., McGuire PJ; National Human Genome Research Institute (NHGRI), NIH, Bethesda, MD, USA., Pittaluga S; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute (NCI), NIH, Bethesda, MD, USA., Germain RN; Center for Advanced Tissue Imaging, LISB, NIAID, NIH, Bethesda, MD, USA.; Lymphocyte Biology Section, LISB, NIAID, NIH, Bethesda, MD, USA., Apps R; Center for Human Immunology, NIAID, NIH, Bethesda, MD, USA., Schwartz DM; Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD, USA., Sadtler K; Laboratory of Immuno-Engineering, National Institute of Biomedical Imaging and Bioengineering (NIBIB), NIH, Bethesda, MD, USA., Moir S; B-cell Immunology Section, Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD, USA., Chertow DS; Emerging Pathogens Section, Critical Care Medicine Department, Clinical Center (CC), NIH, Bethesda, MD, USA.; Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD, USA., Kleinstein SH; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Khurana S; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), Silver Spring, MD, USA., Tsang JS; Center for Human Immunology, NIAID, NIH, Bethesda, MD, USA.; Multiscale Systems Biology Section, LISB, NIAID, NIH, Bethesda, MD, USA., Mudd P; Division of Pediatric Otolaryngology, Children's National Hospital, Washington, DC, USA.; Division of Otolaryngology, Department of Surgery, George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Schwartzberg PL; Cell Signaling and Immunity Section, Laboratory of Immune System Biology (LISB), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA. pams@nih.gov.; National Human Genome Research Institute (NHGRI), NIH, Bethesda, MD, USA. pams@nih.gov., Manthiram K; Cell Signaling and Immunity Section, Laboratory of Immune System Biology (LISB), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA. kalpana.manthiram@nih.gov.
Source: Nature immunology [Nat Immunol] 2023 Jan; Vol. 24 (1), pp. 186-199. Date of Electronic Publication: 2022 Dec 19.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, P.H.S.
Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children.
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  Data: <searchLink fieldCode="AU" term="%22Xu+Q%22">Xu Q</searchLink>; Cell Signaling and Immunity Section, Laboratory of Immune System Biology (LISB), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Milanez-Almeida+P%22">Milanez-Almeida P</searchLink>; Center for Human Immunology, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Martins+AJ%22">Martins AJ</searchLink>; Multiscale Systems Biology Section, LISB, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Radtke+AJ%22">Radtke AJ</searchLink>; Center for Advanced Tissue Imaging, LISB, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Hoehn+KB%22">Hoehn KB</searchLink>; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Oguz+C%22">Oguz C</searchLink>; NIAID Collaborative Bioinformatics Resource (NCBR), NIAID, NIH, Bethesda, MD, USA.; 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  Data: <searchLink fieldCode="JN" term="%22100941354%22">Nature immunology</searchLink> [Nat Immunol] 2023 Jan; Vol. 24 (1), pp. 186-199. <i>Date of Electronic Publication: </i>2022 Dec 19.
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