Returning integrated genomic risk and clinical recommendations: The eMERGE study.

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Title: Returning integrated genomic risk and clinical recommendations: The eMERGE study.
Authors: Linder JE; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN., Allworth A; Division of Medical Genetics, Department of Medicine, University of Washington Medical Center, Seattle, WA., Bland HT; Department of Biomedical Informatics and Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Caraballo PJ; Department of Internal Medicine and Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN., Chisholm RL; Center for Genetic Medicine, Northwestern University, Chicago, IL., Clayton EW; Center for Biomedical Ethics and Society, Vanderbilt University Medical Center, Nashville, TN., Crosslin DR; Division of Biomedical Informatics and Genomics, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA., Dikilitas O; Mayo Clinician Investigator Training Program, Department of Internal Medicine and Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN., DiVietro A; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN., Esplin ED; Invitae, San Francisco, CA., Forman S; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN., Freimuth RR; Department of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN., Gordon AS; Department of Pharmacology, Feinberg School of Medicine, and Center for Genetic Medicine, Northwestern University, Chicago, IL., Green R; Department of Biomedical Informatics and Medical Education, University of Washington Medical Center, Seattle, WA., Harden MV; Broad Institute of MIT and Harvard, Cambridge, MA., Holm IA; Division of Genetics and Genomics and Manton Center for Orphan Diseases Research, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, MA., Jarvik GP; Division of Medical Genetics, Department of Medicine and Department of Genome Science, University of Washington Medical Center, Seattle, WA., Karlson EW; Division of Rheumatology, Inflammation and Immunity, Department of Medicine, Brigham and Women's Hospital, Boston, MA., Labrecque S; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN., Lennon NJ; Broad Institute of MIT and Harvard, Cambridge, MA., Limdi NA; Department of Neurology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL., Mittendorf KF; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN., Murphy SN; Department of Neurology, Massachusetts General Hospital, Boston, MA., Orlando L; Center for Applied Genomics and Precision Medicine, Duke University, Durham, NC., Prows CA; Divisions of Human Genetics and Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Rasmussen LV; Department of Preventive Medicine, Northwestern University, Chicago, IL., Rasmussen-Torvik L; Department of Preventive Medicine, Northwestern University, Chicago, IL., Rowley R; Division of Genomic Medicine, National Human Genome Research Institute, Bethesda, MD., Sawicki KT; Department of Cardiology and Center for Genetic Medicine, Northwestern University, Chicago, IL., Schmidlen T; Invitae, San Francisco, CA., Terek S; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA., Veenstra D; School of Pharmacy, University of Washington, Seattle, WA., Velez Edwards DR; Division of Quantitative Science, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Vanderbilt University Medical Center, Nashville, TN., Absher D; Kaiser Permanente Research Bank, Oakland, CA., Abul-Husn NS; Institute for Genomic Health, Department of Medicine, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY., Alsip J; UAB Medicine Enterprise, Birmingham, AL., Bangash H; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN., Beasley M; Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL., Below JE; Division of Genetic Medicine, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN., Berner ES; Department of Health Services Administration, University of Alabama at Birmingham, Birmingham, AL., Booth J; Department of Emergency Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL., Chung WK; Departments of Pediatrics and Medicine, Columbia University Irving Medical Center, Columbia University, New York, NY., Cimino JJ; Division of General Internal Medicine and the Informatics Institute, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL., Connolly J; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA., Davis P; Department of Biomedical Informatics and Medical Education, University of Washington Medical Center, Seattle, WA., Devine B; School of Pharmacy, University of Washington, Seattle, WA., Fullerton SM; Department of Bioethics and Humanities, University of Washington School of Medicine, Seattle, WA., Guiducci C; Broad Institute of MIT and Harvard, Cambridge, MA., Habrat ML; Department of Biomedical Informatics and Medical Education, University of Washington Medical Center, Seattle, WA., Hain H; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA., Hakonarson H; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA., Harr M; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA., Haverfield E; Invitae, San Francisco, CA., Hernandez V; Mountain Park Health Center, Phoenix, AZ., Hoell C; Department of Obstetrics & Gynecology and Center for Genetic Medicine, Northwestern University, Chicago, IL., Horike-Pyne M; Division of Medical Genetics, Department of Medicine, University of Washington Medical Center, Seattle, WA., Hripcsak G; Department of Biomedical Informatics, Columbia University Irving Medical Center, Columbia University, New York, NY., Irvin MR; Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL., Kachulis C; Broad Institute of MIT and Harvard, Cambridge, MA., Karavite D; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA., Kenny EE; Institute for Genomic Health, Department of Medicine, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY., Khan A; Division of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, NY., Kiryluk K; Division of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, NY., Korf B; Department of Genetics, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL., Kottyan L; The Center for Autoimmune Genomics and Etiology, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Kullo IJ; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN., Larkin K; Broad Institute of MIT and Harvard, Cambridge, MA., Liu C; Department of Biomedical Informatics, Columbia University Irving Medical Center, Columbia University, New York, NY., Malolepsza E; Broad Institute of MIT and Harvard, Cambridge, MA., Manolio TA; Division of Genomic Medicine, National Human Genome Research Institute, Bethesda, MD., May T; Elson S. Floyd College of Medicine, Washington State University, Vancouver, WA., McNally EM; Center for Genetic Medicine, Northwestern University, Chicago, IL., Mentch F; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA., Miller A; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN., Mooney SD; Department of Biomedical Informatics and Medical Education, University of Washington Medical Center, Seattle, WA., Murali P; Division of Medical Genetics, Department of Medicine, University of Washington Medical Center, Seattle, WA., Mutai B; Division of Medical Genetics, Department of Medicine, University of Washington Medical Center, Seattle, WA., Muthu N; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA., Namjou B; The Center for Autoimmune Genomics and Etiology, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Perez EF; Department of Medicine, Brigham and Women's Hospital, Mass General Brigham Personalized Medicine, Boston, MA., Puckelwartz MJ; Department of Pharmacology, Feinberg School of Medicine, and Center for Genetic Medicine, Northwestern University, Chicago, IL., Rakhra-Burris T; Center for Applied Genomics and Precision Medicine, Duke University, Durham, NC., Roden DM; Departments of Medicine, Pharmacology, and Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN., Rosenthal EA; Division of Medical Genetics, Department of Medicine, University of Washington Medical Center, Seattle, WA., Saadatagah S; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN., Sabatello M; Division of Nephrology, Department of Medicine & Division of Ethics, Department of Medical Humanities and Ethics, Columbia University Irving Medical Center, New York, NY., Schaid DJ; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN., Schultz B; Division of Genomic Medicine, National Human Genome Research Institute, Bethesda, MD., Seabolt L; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN., Shaibi GQ; Center for Health Promotion and Disease Prevention, Arizona State University, Phoenix, AZ., Sharp RR; Biomedical Ethics Program, Department of Quantitative Health Science, Mayo Clinic, Rochester, MN., Shirts B; Department of Laboratory Medicine & Pathology, University of Washington Medical Center, Seattle, WA., Smith ME; Department of Cardiology and Center for Genetic Medicine, Northwestern University, Chicago, IL., Smoller JW; Department of Psychiatry and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA., Sterling R; Division of Genomics and Society, National Human Genome Research Institute, Bethesda, MD., Suckiel SA; The Institute for Genomic Health, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY., Thayer J; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA., Tiwari HK; Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL., Trinidad SB; Department of Bioethics and Humanities, University of Washington School of Medicine, Seattle, WA., Walunas T; Department of Medicine and Center for Health Information Partnerships, Northwestern University, Chicago, IL., Wei WQ; Department of Biomedical Informatics and Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Wells QS; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN., Weng C; Department of Biomedical Informatics, Columbia University Irving Medical Center, Columbia University, New York, NY., Wiesner GL; Division of Genetic Medicine, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN., Wiley K; Division of Genomic Medicine, National Human Genome Research Institute, Bethesda, MD., Peterson JF; Center for Precision Medicine, Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN. Electronic address: josh.peterson@vumc.org.
Corporate Authors: eMERGE Consortium
Source: Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2023 Apr; Vol. 25 (4), pp. 100006. Date of Electronic Publication: 2023 Jan 06.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9815831 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0366 (Electronic) Linking ISSN: 10983600 NLM ISO Abbreviation: Genet Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1530-0366
DOI:10.1016/j.gim.2023.100006