High-dose carfilzomib achieves superior anti-tumor activity over low-dose and recaptures response in relapsed/refractory multiple myeloma resistant to lowdose carfilzomib by co-inhibiting the β2 and β1 subunits of the proteasome complex.
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| Title: | High-dose carfilzomib achieves superior anti-tumor activity over low-dose and recaptures response in relapsed/refractory multiple myeloma resistant to lowdose carfilzomib by co-inhibiting the β2 and β1 subunits of the proteasome complex. |
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| Authors: | Zhou X; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Besse A; Experimental Oncology and Hematology, Department of Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen., Peter J; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Steinhardt MJ; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Vogt C; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Nerreter S; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Teufel E; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Stanojkovska E; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Xiao X; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Hornburger H; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Haertle L; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Lopez MM; Experimental Oncology and Hematology, Department of Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen., Munawar U; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Riedel A; Mildred Scheel Early Career Center, University of Würzburg, Würzburg., Han S; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Maurits E; Gorlaeus Laboratories, Leiden Institute of Chemistry and Netherlands Proteomics Centre, Leiden., Overkleeft HS; Gorlaeus Laboratories, Leiden Institute of Chemistry and Netherlands Proteomics Centre, Leiden., Florea B; Gorlaeus Laboratories, Leiden Institute of Chemistry and Netherlands Proteomics Centre, Leiden., Einsele H; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Kortüm KM; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Driessen C; Experimental Oncology and Hematology, Department of Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen. christoph.driessen@kssg.ch., Besse L; Experimental Oncology and Hematology, Department of Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen., Rasche L; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany; Mildred Scheel Early Career Center, University of Würzburg, Würzburg. |
| Source: | Haematologica [Haematologica] 2023 Jun 01; Vol. 108 (6), pp. 1628-1639. Date of Electronic Publication: 2023 Jun 01. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Electronic Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 36727403 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: High-dose carfilzomib achieves superior anti-tumor activity over low-dose and recaptures response in relapsed/refractory multiple myeloma resistant to lowdose carfilzomib by co-inhibiting the β2 and β1 subunits of the proteasome complex. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Zhou+X%22">Zhou X</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg.<br /><searchLink fieldCode="AU" term="%22Besse+A%22">Besse A</searchLink>; Experimental Oncology and Hematology, Department of Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen.<br /><searchLink fieldCode="AU" term="%22Peter+J%22">Peter J</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg.<br /><searchLink fieldCode="AU" term="%22Steinhardt+MJ%22">Steinhardt MJ</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg.<br /><searchLink fieldCode="AU" term="%22Vogt+C%22">Vogt C</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg.<br /><searchLink fieldCode="AU" term="%22Nerreter+S%22">Nerreter S</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg.<br /><searchLink fieldCode="AU" term="%22Teufel+E%22">Teufel E</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg.<br /><searchLink fieldCode="AU" term="%22Stanojkovska+E%22">Stanojkovska E</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg.<br /><searchLink fieldCode="AU" term="%22Xiao+X%22">Xiao X</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg.<br /><searchLink fieldCode="AU" term="%22Hornburger+H%22">Hornburger H</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg.<br /><searchLink fieldCode="AU" term="%22Haertle+L%22">Haertle L</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg.<br /><searchLink fieldCode="AU" term="%22Lopez+MM%22">Lopez MM</searchLink>; Experimental Oncology and Hematology, Department of Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen.<br /><searchLink fieldCode="AU" term="%22Munawar+U%22">Munawar U</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg.<br /><searchLink fieldCode="AU" term="%22Riedel+A%22">Riedel A</searchLink>; Mildred Scheel Early Career Center, University of Würzburg, Würzburg.<br /><searchLink fieldCode="AU" term="%22Han+S%22">Han S</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg.<br /><searchLink fieldCode="AU" term="%22Maurits+E%22">Maurits E</searchLink>; Gorlaeus Laboratories, Leiden Institute of Chemistry and Netherlands Proteomics Centre, Leiden.<br /><searchLink fieldCode="AU" term="%22Overkleeft+HS%22">Overkleeft HS</searchLink>; Gorlaeus Laboratories, Leiden Institute of Chemistry and Netherlands Proteomics Centre, Leiden.<br /><searchLink fieldCode="AU" term="%22Florea+B%22">Florea B</searchLink>; Gorlaeus Laboratories, Leiden Institute of Chemistry and Netherlands Proteomics Centre, Leiden.<br /><searchLink fieldCode="AU" term="%22Einsele+H%22">Einsele H</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg.<br /><searchLink fieldCode="AU" term="%22Kortüm+KM%22">Kortüm KM</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg.<br /><searchLink fieldCode="AU" term="%22Driessen+C%22">Driessen C</searchLink>; Experimental Oncology and Hematology, Department of Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen. christoph.driessen@kssg.ch.<br /><searchLink fieldCode="AU" term="%22Besse+L%22">Besse L</searchLink>; Experimental Oncology and Hematology, Department of Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen.<br /><searchLink fieldCode="AU" term="%22Rasche+L%22">Rasche L</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany; Mildred Scheel Early Career Center, University of Würzburg, Würzburg. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220417435%22">Haematologica</searchLink> [Haematologica] 2023 Jun 01; Vol. 108 (6), pp. 1628-1639. <i>Date of Electronic Publication: </i>2023 Jun 01. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ferrata+Storti+Foundation%22">Ferrata Storti Foundation </searchLink><i>Country of Publication: </i>Italy <i>NLM ID: </i>0417435 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1592-8721 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203906078%22">03906078 </searchLink><i>NLM ISO Abbreviation: </i>Haematologica <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=36727403 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3324/haematol.2022.282225 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1628 Titles: – TitleFull: High-dose carfilzomib achieves superior anti-tumor activity over low-dose and recaptures response in relapsed/refractory multiple myeloma resistant to lowdose carfilzomib by co-inhibiting the β2 and β1 subunits of the proteasome complex. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zhou X – PersonEntity: Name: NameFull: Besse A – PersonEntity: Name: NameFull: Peter J – PersonEntity: Name: NameFull: Steinhardt MJ – PersonEntity: Name: NameFull: Vogt C – PersonEntity: Name: NameFull: Nerreter S – PersonEntity: Name: NameFull: Teufel E – PersonEntity: Name: NameFull: Stanojkovska E – PersonEntity: Name: NameFull: Xiao X – PersonEntity: Name: NameFull: Hornburger H – PersonEntity: Name: NameFull: Haertle L – PersonEntity: Name: NameFull: Lopez MM – PersonEntity: Name: NameFull: Munawar U – PersonEntity: Name: NameFull: Riedel A – PersonEntity: Name: NameFull: Han S – PersonEntity: Name: NameFull: Maurits E – PersonEntity: Name: NameFull: Overkleeft HS – PersonEntity: Name: NameFull: Florea B – PersonEntity: Name: NameFull: Einsele H – PersonEntity: Name: NameFull: Kortüm KM – PersonEntity: Name: NameFull: Driessen C – PersonEntity: Name: NameFull: Besse L – PersonEntity: Name: NameFull: Rasche L IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2023 Jun 01 Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 1592-8721 Numbering: – Type: volume Value: 108 – Type: issue Value: 6 Titles: – TitleFull: Haematologica Type: main |
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