High-dose carfilzomib achieves superior anti-tumor activity over low-dose and recaptures response in relapsed/refractory multiple myeloma resistant to lowdose carfilzomib by co-inhibiting the β2 and β1 subunits of the proteasome complex.
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| Title: | High-dose carfilzomib achieves superior anti-tumor activity over low-dose and recaptures response in relapsed/refractory multiple myeloma resistant to lowdose carfilzomib by co-inhibiting the β2 and β1 subunits of the proteasome complex. |
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| Authors: | Zhou X; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Besse A; Experimental Oncology and Hematology, Department of Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen., Peter J; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Steinhardt MJ; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Vogt C; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Nerreter S; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Teufel E; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Stanojkovska E; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Xiao X; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Hornburger H; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Haertle L; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Lopez MM; Experimental Oncology and Hematology, Department of Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen., Munawar U; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Riedel A; Mildred Scheel Early Career Center, University of Würzburg, Würzburg., Han S; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Maurits E; Gorlaeus Laboratories, Leiden Institute of Chemistry and Netherlands Proteomics Centre, Leiden., Overkleeft HS; Gorlaeus Laboratories, Leiden Institute of Chemistry and Netherlands Proteomics Centre, Leiden., Florea B; Gorlaeus Laboratories, Leiden Institute of Chemistry and Netherlands Proteomics Centre, Leiden., Einsele H; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Kortüm KM; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg., Driessen C; Experimental Oncology and Hematology, Department of Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen. christoph.driessen@kssg.ch., Besse L; Experimental Oncology and Hematology, Department of Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen., Rasche L; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany; Mildred Scheel Early Career Center, University of Würzburg, Würzburg. |
| Source: | Haematologica [Haematologica] 2023 Jun 01; Vol. 108 (6), pp. 1628-1639. Date of Electronic Publication: 2023 Jun 01. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Electronic Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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