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The neuronal pentraxin Nptx2 regulates complement activity and restrains microglia-mediated synapse loss in neurodegeneration.

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Title: The neuronal pentraxin Nptx2 regulates complement activity and restrains microglia-mediated synapse loss in neurodegeneration.
Authors: Zhou J; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, 21205, USA., Wade SD; Broad Institute of MIT and Harvard, Cambridge, 02142, USA., Graykowski D; Broad Institute of MIT and Harvard, Cambridge, 02142, USA., Xiao MF; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, 21205, USA., Zhao B; Broad Institute of MIT and Harvard, Cambridge, 02142, USA., Giannini LAA; Alzheimer Center, Department of Neurology, Erasmus University Medical Center, Rotterdam, 3015 GD, Netherlands., Hanson JE; Genentech, Neuroscience, South San Francisco, 94080, USA., van Swieten JC; Alzheimer Center, Department of Neurology, Erasmus University Medical Center, Rotterdam, 3015 GD, Netherlands., Sheng M; Broad Institute of MIT and Harvard, Cambridge, 02142, USA., Worley PF; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, 21205, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, 21205, USA., Dejanovic B; Broad Institute of MIT and Harvard, Cambridge, 02142, USA.
Source: Science translational medicine [Sci Transl Med] 2023 Mar 29; Vol. 15 (689), pp. eadf0141. Date of Electronic Publication: 2023 Mar 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The neuronal pentraxin Nptx2 regulates complement activity and restrains microglia-mediated synapse loss in neurodegeneration.
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  Data: <searchLink fieldCode="AU" term="%22Zhou+J%22">Zhou J</searchLink>; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, 21205, USA.<br /><searchLink fieldCode="AU" term="%22Wade+SD%22">Wade SD</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, USA.<br /><searchLink fieldCode="AU" term="%22Graykowski+D%22">Graykowski D</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, USA.<br /><searchLink fieldCode="AU" term="%22Xiao+MF%22">Xiao MF</searchLink>; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, 21205, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+B%22">Zhao B</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, USA.<br /><searchLink fieldCode="AU" term="%22Giannini+LAA%22">Giannini LAA</searchLink>; Alzheimer Center, Department of Neurology, Erasmus University Medical Center, Rotterdam, 3015 GD, Netherlands.<br /><searchLink fieldCode="AU" term="%22Hanson+JE%22">Hanson JE</searchLink>; Genentech, Neuroscience, South San Francisco, 94080, USA.<br /><searchLink fieldCode="AU" term="%22van+Swieten+JC%22">van Swieten JC</searchLink>; Alzheimer Center, Department of Neurology, Erasmus University Medical Center, Rotterdam, 3015 GD, Netherlands.<br /><searchLink fieldCode="AU" term="%22Sheng+M%22">Sheng M</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, USA.<br /><searchLink fieldCode="AU" term="%22Worley+PF%22">Worley PF</searchLink>; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, 21205, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, 21205, USA.<br /><searchLink fieldCode="AU" term="%22Dejanovic+B%22">Dejanovic B</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142, USA.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2023 Mar 29; Vol. 15 (689), pp. eadf0141. <i>Date of Electronic Publication: </i>2023 Mar 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101505086 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1946-6242 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219466234%22">19466234 </searchLink><i>NLM ISO Abbreviation: </i>Sci Transl Med <i>Subsets: </i>MEDLINE
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        Value: 10.1126/scitranslmed.adf0141
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              Text: 2023 Mar 29
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