The neuronal pentraxin Nptx2 regulates complement activity and restrains microglia-mediated synapse loss in neurodegeneration.
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| Title: | The neuronal pentraxin Nptx2 regulates complement activity and restrains microglia-mediated synapse loss in neurodegeneration. |
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| Authors: | Zhou J; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, 21205, USA., Wade SD; Broad Institute of MIT and Harvard, Cambridge, 02142, USA., Graykowski D; Broad Institute of MIT and Harvard, Cambridge, 02142, USA., Xiao MF; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, 21205, USA., Zhao B; Broad Institute of MIT and Harvard, Cambridge, 02142, USA., Giannini LAA; Alzheimer Center, Department of Neurology, Erasmus University Medical Center, Rotterdam, 3015 GD, Netherlands., Hanson JE; Genentech, Neuroscience, South San Francisco, 94080, USA., van Swieten JC; Alzheimer Center, Department of Neurology, Erasmus University Medical Center, Rotterdam, 3015 GD, Netherlands., Sheng M; Broad Institute of MIT and Harvard, Cambridge, 02142, USA., Worley PF; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, 21205, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, 21205, USA., Dejanovic B; Broad Institute of MIT and Harvard, Cambridge, 02142, USA. |
| Source: | Science translational medicine [Sci Transl Med] 2023 Mar 29; Vol. 15 (689), pp. eadf0141. Date of Electronic Publication: 2023 Mar 29. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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