Heterozygous midnolin knockout attenuates severity of nonalcoholic fatty liver disease in mice fed a Western-style diet high in fat, cholesterol, and fructose.

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Title: Heterozygous midnolin knockout attenuates severity of nonalcoholic fatty liver disease in mice fed a Western-style diet high in fat, cholesterol, and fructose.
Authors: Kweon SM; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, United States., Irimia-Dominguez J; Department of Molecular and Cellular Endocrinology and Comprehensive Metabolic Phenotyping Core, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, California, United States., Kim G; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, United States., Fueger PT; Department of Molecular and Cellular Endocrinology and Comprehensive Metabolic Phenotyping Core, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, California, United States.; City of Hope Comprehensive Cancer Center, Duarte, California, United States., Asahina K; Central Research Laboratory, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Japan., Lai KK; Department of Pathology, Cleveland Clinic, Cleveland, Ohio, United States.; Contra Costa Pathology Associates, Pleasant Hill, California, United States., Allende DS; Department of Pathology, Cleveland Clinic, Cleveland, Ohio, United States., Lai QR; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, United States., Lou CH; Gene Editing and Viral Vector Core, Beckman Research Institute of City of Hope, Duarte, California, United States., Tsark WM; Transgenic/Knockout Mouse Program, Center for Comparative Medicine, Beckman Research Institute of City of Hope, Duarte, California, United States., Yang JD; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, California, United States.; Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, California, United States.; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States., Ng DS; Departments of Medicine, Physiology, and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Lee JS; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States., Tso P; Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States., Huang W; Department of Diabetes Complications and Metabolism, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, California, United States.; City of Hope Comprehensive Cancer Center, Duarte, California, United States., Lai KKY; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, United States.; City of Hope Comprehensive Cancer Center, Duarte, California, United States.
Source: American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2023 Aug 01; Vol. 325 (2), pp. G147-G157. Date of Electronic Publication: 2023 May 02.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901227 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1547 (Electronic) Linking ISSN: 01931857 NLM ISO Abbreviation: Am J Physiol Gastrointest Liver Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Heterozygous midnolin knockout attenuates severity of nonalcoholic fatty liver disease in mice fed a Western-style diet high in fat, cholesterol, and fructose.
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  Data: <searchLink fieldCode="AU" term="%22Kweon+SM%22">Kweon SM</searchLink>; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, United States.<br /><searchLink fieldCode="AU" term="%22Irimia-Dominguez+J%22">Irimia-Dominguez J</searchLink>; Department of Molecular and Cellular Endocrinology and Comprehensive Metabolic Phenotyping Core, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, California, United States.<br /><searchLink fieldCode="AU" term="%22Kim+G%22">Kim G</searchLink>; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, United States.<br /><searchLink fieldCode="AU" term="%22Fueger+PT%22">Fueger PT</searchLink>; Department of Molecular and Cellular Endocrinology and Comprehensive Metabolic Phenotyping Core, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, California, United States.; City of Hope Comprehensive Cancer Center, Duarte, California, United States.<br /><searchLink fieldCode="AU" term="%22Asahina+K%22">Asahina K</searchLink>; Central Research Laboratory, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Japan.<br /><searchLink fieldCode="AU" term="%22Lai+KK%22">Lai KK</searchLink>; Department of Pathology, Cleveland Clinic, Cleveland, Ohio, United States.; Contra Costa Pathology Associates, Pleasant Hill, California, United States.<br /><searchLink fieldCode="AU" term="%22Allende+DS%22">Allende DS</searchLink>; Department of Pathology, Cleveland Clinic, Cleveland, Ohio, United States.<br /><searchLink fieldCode="AU" term="%22Lai+QR%22">Lai QR</searchLink>; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, United States.<br /><searchLink fieldCode="AU" term="%22Lou+CH%22">Lou CH</searchLink>; Gene Editing and Viral Vector Core, Beckman Research Institute of City of Hope, Duarte, California, United States.<br /><searchLink fieldCode="AU" term="%22Tsark+WM%22">Tsark WM</searchLink>; Transgenic/Knockout Mouse Program, Center for Comparative Medicine, Beckman Research Institute of City of Hope, Duarte, California, United States.<br /><searchLink fieldCode="AU" term="%22Yang+JD%22">Yang JD</searchLink>; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, California, United States.; Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, California, United States.; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States.<br /><searchLink fieldCode="AU" term="%22Ng+DS%22">Ng DS</searchLink>; Departments of Medicine, Physiology, and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Lee+JS%22">Lee JS</searchLink>; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States.<br /><searchLink fieldCode="AU" term="%22Tso+P%22">Tso P</searchLink>; Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States.<br /><searchLink fieldCode="AU" term="%22Huang+W%22">Huang W</searchLink>; Department of Diabetes Complications and Metabolism, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, California, United States.; City of Hope Comprehensive Cancer Center, Duarte, California, United States.<br /><searchLink fieldCode="AU" term="%22Lai+KKY%22">Lai KKY</searchLink>; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California, United States.; City of Hope Comprehensive Cancer Center, Duarte, California, United States.
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  Data: <searchLink fieldCode="JN" term="%22100901227%22">American journal of physiology. Gastrointestinal and liver physiology</searchLink> [Am J Physiol Gastrointest Liver Physiol] 2023 Aug 01; Vol. 325 (2), pp. G147-G157. <i>Date of Electronic Publication: </i>2023 May 02.
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        Value: 10.1152/ajpgi.00011.2023
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        Text: English
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