Neurovascular coupling is optimized to compensate for the increase in proton production from nonoxidative glycolysis and glycogenolysis during brain activation and maintain homeostasis of pH, pCO2, and pO2.

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Title: Neurovascular coupling is optimized to compensate for the increase in proton production from nonoxidative glycolysis and glycogenolysis during brain activation and maintain homeostasis of pH, pCO2, and pO2.
Authors: DiNuzzo M; Centro Ricerche Enrico Fermi, Rome, Italy., Dienel GA; Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.; Department of Cell Biology and Physiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA., Behar KL; Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA., Petroff OA; Department of Neurology, Yale University School of Medicine, New Haven, Connecticut, USA., Benveniste H; Department of Anesthesiology, Yale University, New Haven, Connecticut, USA.; Department of Biomedical Engineering, Yale University, New Haven, Connecticut, USA., Hyder F; Department of Biomedical Engineering, Yale University, New Haven, Connecticut, USA.; Department of Radiology, Magnetic Resonance Research Center (MRRC), Yale University, New Haven, Connecticut, USA., Giove F; Centro Ricerche Enrico Fermi, Rome, Italy.; Fondazione Santa Lucia IRCCS, Rome, Italy., Michaeli S; Department of Radiology, Center for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, Minnesota, USA., Mangia S; Department of Radiology, Center for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, Minnesota, USA., Herculano-Houzel S; Department of Psychology, Vanderbilt University, Nashville, Tennessee, USA.; Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt Brain Institute, Vanderbilt University, Nashville, Tennessee, USA., Rothman DL; Department of Biomedical Engineering, Yale University, New Haven, Connecticut, USA.; Department of Radiology, Magnetic Resonance Research Center (MRRC), Yale University, New Haven, Connecticut, USA.
Source: Journal of neurochemistry [J Neurochem] 2024 May; Vol. 168 (5), pp. 632-662. Date of Electronic Publication: 2023 Jun 21.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-4159 (Electronic) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1471-4159
DOI:10.1111/jnc.15839