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Effect of Dupilumab on Type 2 Biomarkers in Chronic Rhinosinusitis With Nasal Polyps: SINUS-52 Study Results.

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Title: Effect of Dupilumab on Type 2 Biomarkers in Chronic Rhinosinusitis With Nasal Polyps: SINUS-52 Study Results.
Authors: Bachert C; Department of Otorhinolaryngology - Head and Neck Surgery, University Hospital of Münster, Münster, Germany.; First Affiliated Hospital, Sun Yat-Sen University, International Airway Research Center, Guangzhou, China.; Upper Airways Research Laboratory, Faculty of Medicine, Ghent University, Ghent, Belgium., Laidlaw TM; Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Cho SH; Division of Allergy-Immunology, Morsani College of Medicine, University of South Florida, Tampa, FL, USA., Mullol J; Rhinology Unit & Smell Clinic, ENT Department, Hospital Clínic, IDIBAPS, Universitat de Barcelona, CIBERES, Barcelona, Catalonia, Spain., Swanson BN; College of Life Sciences, Thomas Jefferson University, Philadelphia, PA, USA.; Research and Development, Sanofi, Bridgewater, NJ, USA., Naimi S; Molecular and Digital Histopathology, Sanofi, Vitry-sur-Seine, France., Classe M; Pathology Department, Institut Gustave Roussy, Villejuif, France.; Translational Sciences, Sanofi, Chilly-Mazarin, France., Harel S; Clinical Sciences Global Development, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA., Jagerschmidt A; Global Clinical Development, Sanofi, Chilly-Mazarin, France., Laws E; Immunology and Inflammation Global Development, Sanofi, Bridgewater, NJ, USA., Ruddy M; Clinical Sciences Global Development, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA., Praestgaard A; Department of Biostatistics, Sanofi, Cambridge, MA, USA., Amin N; Clinical Sciences Global Development, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA., Mannent LP; Global Clinical Development, Sanofi, Chilly-Mazarin, France.
Source: The Annals of otology, rhinology, and laryngology [Ann Otol Rhinol Laryngol] 2023 Dec; Vol. 132 (12), pp. 1649-1661. Date of Electronic Publication: 2023 Jun 15.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Sage Country of Publication: United States NLM ID: 0407300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-572X (Electronic) Linking ISSN: 00034894 NLM ISO Abbreviation: Ann Otol Rhinol Laryngol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effect of Dupilumab on Type 2 Biomarkers in Chronic Rhinosinusitis With Nasal Polyps: SINUS-52 Study Results.
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  Data: <searchLink fieldCode="AU" term="%22Bachert+C%22">Bachert C</searchLink>; Department of Otorhinolaryngology - Head and Neck Surgery, University Hospital of Münster, Münster, Germany.; First Affiliated Hospital, Sun Yat-Sen University, International Airway Research Center, Guangzhou, China.; Upper Airways Research Laboratory, Faculty of Medicine, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Laidlaw+TM%22">Laidlaw TM</searchLink>; Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cho+SH%22">Cho SH</searchLink>; Division of Allergy-Immunology, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Mullol+J%22">Mullol J</searchLink>; Rhinology Unit & Smell Clinic, ENT Department, Hospital Clínic, IDIBAPS, Universitat de Barcelona, CIBERES, Barcelona, Catalonia, Spain.<br /><searchLink fieldCode="AU" term="%22Swanson+BN%22">Swanson BN</searchLink>; College of Life Sciences, Thomas Jefferson University, Philadelphia, PA, USA.; Research and Development, Sanofi, Bridgewater, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Naimi+S%22">Naimi S</searchLink>; Molecular and Digital Histopathology, Sanofi, Vitry-sur-Seine, France.<br /><searchLink fieldCode="AU" term="%22Classe+M%22">Classe M</searchLink>; Pathology Department, Institut Gustave Roussy, Villejuif, France.; Translational Sciences, Sanofi, Chilly-Mazarin, France.<br /><searchLink fieldCode="AU" term="%22Harel+S%22">Harel S</searchLink>; Clinical Sciences Global Development, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Jagerschmidt+A%22">Jagerschmidt A</searchLink>; Global Clinical Development, Sanofi, Chilly-Mazarin, France.<br /><searchLink fieldCode="AU" term="%22Laws+E%22">Laws E</searchLink>; Immunology and Inflammation Global Development, Sanofi, Bridgewater, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Ruddy+M%22">Ruddy M</searchLink>; Clinical Sciences Global Development, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Praestgaard+A%22">Praestgaard A</searchLink>; Department of Biostatistics, Sanofi, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Amin+N%22">Amin N</searchLink>; Clinical Sciences Global Development, Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mannent+LP%22">Mannent LP</searchLink>; Global Clinical Development, Sanofi, Chilly-Mazarin, France.
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  Data: <searchLink fieldCode="JN" term="%220407300%22">The Annals of otology, rhinology, and laryngology</searchLink> [Ann Otol Rhinol Laryngol] 2023 Dec; Vol. 132 (12), pp. 1649-1661. <i>Date of Electronic Publication: </i>2023 Jun 15.
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