Ganaplacide (KAF156) plus lumefantrine solid dispersion formulation combination for uncomplicated Plasmodium falciparum malaria: an open-label, multicentre, parallel-group, randomised, controlled, phase 2 trial.
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| Title: | Ganaplacide (KAF156) plus lumefantrine solid dispersion formulation combination for uncomplicated Plasmodium falciparum malaria: an open-label, multicentre, parallel-group, randomised, controlled, phase 2 trial. |
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| Authors: | Ogutu B; Centre for Clinical Research, Kenya Medical Research Institute, Kisumu, Kenya., Yeka A; Infectious Diseases Research Collaboration, Kampala, Uganda., Kusemererwa S; Medical Research Council, Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda., Thompson R; Chókwè Health Research and Training Center, Centro de Investigação e Treino em Saúde de Chókwè, National Institute of Health, Chókwè, Mozambique., Tinto H; Institut de Recherche en Science de la Santé, Unité de Recherche Clinique de Nanoro, Nanoro, Burkina Faso., Toure AO; Department of Parasitology and Mycology, Institut Pasteur de Côte d'Ivoire, Abidjan, Côte d'Ivoire., Uthaisin C; Mae Ramat Hospital, Tak, Thailand., Verma A; Department of Paediatrics, Rajendra Institute of Medical Sciences, Jharkhand, India., Kibuuka A; Infectious Diseases Research Collaboration, Kampala, Uganda., Lingani M; Institut de Recherche en Science de la Santé, Unité de Recherche Clinique de Nanoro, Nanoro, Burkina Faso., Lourenço C; Chókwè Health Research and Training Center, Centro de Investigação e Treino em Saúde de Chókwè, National Institute of Health, Chókwè, Mozambique., Mombo-Ngoma G; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Department of Implementation Research, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany; Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Nduba V; Kenya Medical Research Institute, Centre for Respiratory Diseases Research, Nairobi, Kenya., N'Guessan TL; Department of Parasitology and Mycology, Institut Pasteur de Côte d'Ivoire, Abidjan, Côte d'Ivoire., Nassa GJW; Institut de Recherche en Science de la Santé, Unité de Recherche Clinique de Nanoro, Nanoro, Burkina Faso., Nyantaro M; Medical Research Council, Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda., Tina LO; Centre for Clinical Research, Kenya Medical Research Institute, US Army Medical Research Directorate, Kisumu, Kenya., Singh PK; ICMR-National Institute of Malaria Research, Ranchi, India., El Gaaloul M; Medicines for Malaria Venture, Geneva, Switzerland., Marrast AC; Medicines for Malaria Venture, Geneva, Switzerland., Chikoto H; Novartis Pharma, Basel, Switzerland., Csermak K; Novartis Pharma, Basel, Switzerland., Demin I; Novartis Pharma, Basel, Switzerland., Mehta D; Novartis Healthcare, Hyderabad, India., Pathan R; Novartis Healthcare, Hyderabad, India., Risterucci C; Novartis Pharma, Basel, Switzerland., Su G; Novartis Pharmaceuticals, East Hanover, NJ, USA., Winnips C; Novartis Pharma, Basel, Switzerland., Kaguthi G; Kenya Medical Research Institute, Centre for Respiratory Diseases Research, Nairobi, Kenya., Fofana B; Malaria Research and Training Center, Bamako, Mali., Grobusch MP; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Department of Infectious Diseases, Center of Tropical Medicine and Travel Medicine, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, Netherlands; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany. Electronic address: m.p.grobusch@amsterdamumc.nl. |
| Source: | The Lancet. Infectious diseases [Lancet Infect Dis] 2023 Sep; Vol. 23 (9), pp. 1051-1061. Date of Electronic Publication: 2023 Jun 13. |
| Publication Type: | Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Science Country of Publication: United States NLM ID: 101130150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-4457 (Electronic) Linking ISSN: 14733099 NLM ISO Abbreviation: Lancet Infect Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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