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Single-cell transcriptomics reveals maturation of transplanted stem cell-derived retinal pigment epithelial cells toward native state.

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Title: Single-cell transcriptomics reveals maturation of transplanted stem cell-derived retinal pigment epithelial cells toward native state.
Authors: Parikh BH; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore., Blakeley P; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore., Regha K; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore., Liu Z; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.; Singapore Eye Research Institute, Singapore 169856, Singapore., Yang B; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore., Bhargava M; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.; Department of Ophthalmology, National University Hospital, Singapore 119074, Singapore., Wong DSL; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore., Tan QSW; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore., Wong CSW; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore., Wang HF; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore., Al-Mubaarak A; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore., Chou C; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore., Cheung CMG; Singapore Eye Research Institute, Singapore 169856, Singapore., Lim KL; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore., Barathi VA; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.; Singapore Eye Research Institute, Singapore 169856, Singapore.; Academic Clinical Program in Ophthalmology, Duke-NUS Medical School, Singapore 169857, Singapore., Hunziker W; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117593, Singapore., Lingam G; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.; Singapore Eye Research Institute, Singapore 169856, Singapore.; Department of Ophthalmology, National University Hospital, Singapore 119074, Singapore., Hu TX; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore., Su X; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.; Singapore Eye Research Institute, Singapore 169856, Singapore.; Department of Ophthalmology, National University Hospital, Singapore 119074, Singapore.; Institute of Health Innovation and Technology, National University of Singapore, Singapore 119276, Singapore.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Jun 27; Vol. 120 (26), pp. e2214842120. Date of Electronic Publication: 2023 Jun 20.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: Single-cell transcriptomics reveals maturation of transplanted stem cell-derived retinal pigment epithelial cells toward native state.
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  Data: <searchLink fieldCode="AU" term="%22Parikh+BH%22">Parikh BH</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Blakeley+P%22">Blakeley P</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Regha+K%22">Regha K</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.; Singapore Eye Research Institute, Singapore 169856, Singapore.<br /><searchLink fieldCode="AU" term="%22Yang+B%22">Yang B</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Bhargava+M%22">Bhargava M</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.; Department of Ophthalmology, National University Hospital, Singapore 119074, Singapore.<br /><searchLink fieldCode="AU" term="%22Wong+DSL%22">Wong DSL</searchLink>; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+QSW%22">Tan QSW</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Wong+CSW%22">Wong CSW</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Wang+HF%22">Wang HF</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Al-Mubaarak+A%22">Al-Mubaarak A</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Chou+C%22">Chou C</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore.<br /><searchLink fieldCode="AU" term="%22Cheung+CMG%22">Cheung CMG</searchLink>; Singapore Eye Research Institute, Singapore 169856, Singapore.<br /><searchLink fieldCode="AU" term="%22Lim+KL%22">Lim KL</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore.<br /><searchLink fieldCode="AU" term="%22Barathi+VA%22">Barathi VA</searchLink>; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.; Singapore Eye Research Institute, Singapore 169856, Singapore.; Academic Clinical Program in Ophthalmology, Duke-NUS Medical School, Singapore 169857, Singapore.<br /><searchLink fieldCode="AU" term="%22Hunziker+W%22">Hunziker W</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117593, Singapore.<br /><searchLink fieldCode="AU" term="%22Lingam+G%22">Lingam G</searchLink>; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.; Singapore Eye Research Institute, Singapore 169856, Singapore.; Department of Ophthalmology, National University Hospital, Singapore 119074, Singapore.<br /><searchLink fieldCode="AU" term="%22Hu+TX%22">Hu TX</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Su+X%22">Su X</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.; Singapore Eye Research Institute, Singapore 169856, Singapore.; Department of Ophthalmology, National University Hospital, Singapore 119074, Singapore.; Institute of Health Innovation and Technology, National University of Singapore, Singapore 119276, Singapore.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2023 Jun 27; Vol. 120 (26), pp. e2214842120. <i>Date of Electronic Publication: </i>2023 Jun 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22National+Academy+of+Sciences%22">National Academy of Sciences </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7505876 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1091-6490 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200278424%22">00278424 </searchLink><i>NLM ISO Abbreviation: </i>Proc Natl Acad Sci U S A <i>Subsets: </i>MEDLINE
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        Value: 10.1073/pnas.2214842120
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