BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor-resistant BRCA-mutant ovarian cancer.
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| Title: | BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor-resistant BRCA-mutant ovarian cancer. |
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| Authors: | Gupta N; Women's Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA., Huang TT; Women's Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA., Nair JR; Women's Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA., An D; Women's Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA., Zurcher G; Women's Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA., Lampert EJ; Women's Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA.; Department of Obstetrics and Gynecology, Cleveland Clinic, Cleveland, OH 44195, USA., McCoy A; Women's Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA., Cimino-Mathews A; Departments of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA., Swisher EM; Brotman Baty Institute of Precision Medicine, University of Washington, Seattle, WA 98195, USA., Radke MR; Brotman Baty Institute of Precision Medicine, University of Washington, Seattle, WA 98195, USA., Lockwood CM; Brotman Baty Institute of Precision Medicine, University of Washington, Seattle, WA 98195, USA.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195, USA., Reichel JB; Brotman Baty Institute of Precision Medicine, University of Washington, Seattle, WA 98195, USA., Chiang CY; National Center for Advancing Translational Sciences, National Institutes of Health (NIH), Rockville, MD 20892, USA., Wilson KM; National Center for Advancing Translational Sciences, National Institutes of Health (NIH), Rockville, MD 20892, USA., Cheng KC; National Center for Advancing Translational Sciences, National Institutes of Health (NIH), Rockville, MD 20892, USA., Nousome D; Center for Cancer Research Collaborative Bioinformatics Resource, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA., Lee JM; Women's Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA. |
| Source: | Science translational medicine [Sci Transl Med] 2023 Jun 21; Vol. 15 (701), pp. eadd7872. Date of Electronic Publication: 2023 Jun 21. |
| Publication Type: | Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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