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Exome Sequencing and the Identification of New Genes and Shared Mechanisms in Polymicrogyria.

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Title: Exome Sequencing and the Identification of New Genes and Shared Mechanisms in Polymicrogyria.
Authors: Akula SK; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts.; Harvard-MIT MD/PhD Program, Harvard Medical School, Boston, Massachusetts., Chen AY; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Division of Rheumatology, Hospital for Special Surgery, New York, New York., Neil JE; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts., Shao DD; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Department of Neurology, Boston Children's Hospital, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts., Mo A; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Department of Neurology, Boston Children's Hospital, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts., Hylton NK; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts.; Harvard-MIT MD/PhD Program, Harvard Medical School, Boston, Massachusetts., DiTroia S; Program in Medical and Population Genetics, Center for Genomic Medicine, Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Ganesh VS; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts., Smith RS; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., O'Kane K; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts., Yeh RC; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts., Marciano JH; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts., Kirkham S; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts., Kenny CJ; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts., Song JHT; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts., Al Saffar M; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts.; Department of Genetics and Genomics, United Arab Emirates University, United Arab Emirates., Millan F; GeneDx, Gaithersburg, Maryland., Harris DJ; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts., Murphy AV; Division of Medical Genetics, Our Lady of the Lake Health System, Baton Rouge, Louisiana., Klemp KC; Division of Medical Genetics, Department of Pediatrics Saint Louis University School of Medicine, St Louis, Missouri., Braddock SR; Division of Medical Genetics, Department of Pediatrics Saint Louis University School of Medicine, St Louis, Missouri., Brand H; Program in Medical and Population Genetics, Center for Genomic Medicine, Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Department of Neurology, Harvard Medical School, Boston, Massachusetts., Wong I; Program in Medical and Population Genetics, Center for Genomic Medicine, Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Department of Neurology, Harvard Medical School, Boston, Massachusetts., Talkowski ME; Program in Medical and Population Genetics, Center for Genomic Medicine, Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Department of Neurology, Harvard Medical School, Boston, Massachusetts., O'Donnell-Luria A; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Program in Medical and Population Genetics, Center for Genomic Medicine, Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Lai A; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Department of Neurology, Boston Children's Hospital, Boston, Massachusetts., Hill RS; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts., Mochida GH; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Department of Neurology, Boston Children's Hospital, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts., Doan RN; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts., Barkovich AJ; Benioff Children's Hospital, Departments of Radiology, Pediatrics, Neurology, and Neurological Surgery, University of California, San Francisco, San Francisco., Yang E; Department of Radiology, Boston Children's Hospital, Boston, Massachusetts., Amrom D; Neurogenetics Unit, Montreal Neurological Hospital and Institute, Montreal, Quebec, Canada.; Department of Neurology & Neurosurgery, McGill University, Montreal, Quebec, Canada.; Department of Neurology, Queen Fabiola Children's University Hospital, Brussels, Belgium.; Pediatric Neurology Unit, Centre Hospitalier de Luxembourg, Grand-Duchy of Luxembourg., Andermann E; Department of Neurology & Neurosurgery, McGill University, Montreal, Quebec, Canada.; Pediatric Neurology Unit, Centre Hospitalier de Luxembourg, Grand-Duchy of Luxembourg.; Epilepsy Research Group, Montreal Neurological Hospital and Institute, Quebec, Canada.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada., Poduri A; Department of Neurology, Boston Children's Hospital, Boston, Massachusetts., Walsh CA; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, and Allen Discovery Center for Human Brain Evolution, Boston, Massachusetts.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts.; Harvard-MIT MD/PhD Program, Harvard Medical School, Boston, Massachusetts.; Program in Medical and Population Genetics, Center for Genomic Medicine, Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Corporate Authors: Polymicrogyria Genetics Research Network
Source: JAMA neurology [JAMA Neurol] 2023 Sep 01; Vol. 80 (9), pp. 980-988.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589536 Publication Model: Print Cited Medium: Internet ISSN: 2168-6157 (Electronic) Linking ISSN: 21686149 NLM ISO Abbreviation: JAMA Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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