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The small molecule Erk1/2 signaling pathway inhibitor PD98059 improves DNA repair in an experimental autoimmune encephalomyelitis SJL/J mouse model of multiple sclerosis.

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Title: The small molecule Erk1/2 signaling pathway inhibitor PD98059 improves DNA repair in an experimental autoimmune encephalomyelitis SJL/J mouse model of multiple sclerosis.
Authors: Attia SM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia. Electronic address: attiasm@ksu.edu.sa., Ahmad SF; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia., Nadeem A; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia., Attia MSM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia., Ansari MA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia., Alsaleh NB; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia., Alasmari AF; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia., Al-Hamamah MA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia., Alanazi A; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia., Alshamrani AA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia., Bakheet SA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia., Harisa GI; Department of Pharmaceutics, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia.
Source: Mutation research. Genetic toxicology and environmental mutagenesis [Mutat Res Genet Toxicol Environ Mutagen] 2023 Jul; Vol. 889, pp. 503650. Date of Electronic Publication: 2023 Jun 03.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101632149 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3592 (Electronic) Linking ISSN: 13835718 NLM ISO Abbreviation: Mutat Res Genet Toxicol Environ Mutagen Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The small molecule Erk1/2 signaling pathway inhibitor PD98059 improves DNA repair in an experimental autoimmune encephalomyelitis SJL/J mouse model of multiple sclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Attia+SM%22">Attia SM</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia. Electronic address: attiasm@ksu.edu.sa.<br /><searchLink fieldCode="AU" term="%22Ahmad+SF%22">Ahmad SF</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Nadeem+A%22">Nadeem A</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Attia+MSM%22">Attia MSM</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Ansari+MA%22">Ansari MA</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alsaleh+NB%22">Alsaleh NB</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alasmari+AF%22">Alasmari AF</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Al-Hamamah+MA%22">Al-Hamamah MA</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alanazi+A%22">Alanazi A</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alshamrani+AA%22">Alshamrani AA</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Bakheet+SA%22">Bakheet SA</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Harisa+GI%22">Harisa GI</searchLink>; Department of Pharmaceutics, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia.
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  Data: <searchLink fieldCode="JN" term="%22101632149%22">Mutation research. Genetic toxicology and environmental mutagenesis</searchLink> [Mutat Res Genet Toxicol Environ Mutagen] 2023 Jul; Vol. 889, pp. 503650. <i>Date of Electronic Publication: </i>2023 Jun 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101632149 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-3592 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213835718%22">13835718 </searchLink><i>NLM ISO Abbreviation: </i>Mutat Res Genet Toxicol Environ Mutagen <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.mrgentox.2023.503650
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              Text: 2023 Jul
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