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Multi-tiered approach to detect autoimmune cross-reactivity of therapeutic T cell receptors.

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Title: Multi-tiered approach to detect autoimmune cross-reactivity of therapeutic T cell receptors.
Authors: Ishii K; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA., Davies JS; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.; Department of Safety Assessment, Genentech Inc., South San Francisco, CA, USA., Sinkoe AL; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA., Nguyen KA; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA., Norberg SM; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA., McIntosh CP; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA., Kadakia T; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.; Precigen, Germantown, MD, USA., Serna C; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.; Oncology Department, Cell Therapy Unit, AstraZeneca, Gaithersburg, MD, USA., Rae Z; Single Cell Analysis Facility, CCR, NCI, NIH, Bethesda, MD, USA.; 10x Genomics, Pleasanton, CA, USA., Kelly MC; Single Cell Analysis Facility, CCR, NCI, NIH, Bethesda, MD, USA., Hinrichs CS; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.; Duncan and Nancy MacMillan Center of Excellence in Cancer Immunotherapy and Metabolism, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
Source: Science advances [Sci Adv] 2023 Jul 28; Vol. 9 (30), pp. eadg9845. Date of Electronic Publication: 2023 Jul 26.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Ishii+K%22">Ishii K</searchLink>; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Davies+JS%22">Davies JS</searchLink>; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.; Department of Safety Assessment, Genentech Inc., South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sinkoe+AL%22">Sinkoe AL</searchLink>; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+KA%22">Nguyen KA</searchLink>; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Norberg+SM%22">Norberg SM</searchLink>; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22McIntosh+CP%22">McIntosh CP</searchLink>; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kadakia+T%22">Kadakia T</searchLink>; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.; Precigen, Germantown, MD, USA.<br /><searchLink fieldCode="AU" term="%22Serna+C%22">Serna C</searchLink>; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.; Oncology Department, Cell Therapy Unit, AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Rae+Z%22">Rae Z</searchLink>; Single Cell Analysis Facility, CCR, NCI, NIH, Bethesda, MD, USA.; 10x Genomics, Pleasanton, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kelly+MC%22">Kelly MC</searchLink>; Single Cell Analysis Facility, CCR, NCI, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Hinrichs+CS%22">Hinrichs CS</searchLink>; Center for Immuno-Oncology, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.; Duncan and Nancy MacMillan Center of Excellence in Cancer Immunotherapy and Metabolism, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
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  Data: <searchLink fieldCode="JN" term="%22101653440%22">Science advances</searchLink> [Sci Adv] 2023 Jul 28; Vol. 9 (30), pp. eadg9845. <i>Date of Electronic Publication: </i>2023 Jul 26.
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              Text: 2023 Jul 28
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