In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene.
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| Title: | In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene. |
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| Authors: | De Giorgi M; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA., Park SH; Department of Bioengineering, Rice University, Houston, TX 77030, USA., Castoreno A; Alnylam Pharmaceuticals Inc, 675 W Kendall St, Cambridge, MA 02142, USA., Cao M; Department of Bioengineering, Rice University, Houston, TX 77030, USA., Hurley A; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA., Saxena L; Department of Bioengineering, Rice University, Houston, TX 77030, USA., Chuecos MA; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.; Translational Biology and Molecular Medicine Program, Baylor College of Medicine, Houston, TX 77030, USA., Walkey CJ; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA., Doerfler AM; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA., Furgurson MN; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA., Ljungberg MC; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.; Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA., Patel KR; Department of Pathology, Texas Children's Hospital, Houston, TX 77030, USA., Hyde S; Alnylam Pharmaceuticals Inc, 675 W Kendall St, Cambridge, MA 02142, USA., Chickering T; Alnylam Pharmaceuticals Inc, 675 W Kendall St, Cambridge, MA 02142, USA., Lefebvre S; Alnylam Pharmaceuticals Inc, 675 W Kendall St, Cambridge, MA 02142, USA., Wassarman K; Alnylam Pharmaceuticals Inc, 675 W Kendall St, Cambridge, MA 02142, USA., Miller P; Alnylam Pharmaceuticals Inc, 675 W Kendall St, Cambridge, MA 02142, USA., Qin J; Alnylam Pharmaceuticals Inc, 675 W Kendall St, Cambridge, MA 02142, USA., Schlegel MK; Alnylam Pharmaceuticals Inc, 675 W Kendall St, Cambridge, MA 02142, USA., Zlatev I; Alnylam Pharmaceuticals Inc, 675 W Kendall St, Cambridge, MA 02142, USA., Li RG; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.; Texas Heart Institute, Houston, TX 77030, USA., Kim J; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.; Texas Heart Institute, Houston, TX 77030, USA., Martin JF; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.; Texas Heart Institute, Houston, TX 77030, USA., Bissig KD; Department of Pediatrics, Alice and Y. T. Chen Center for Genetics and Genomics, Division of Medical Genetics, Duke University, Durham, NC 27710, USA., Jadhav V; Alnylam Pharmaceuticals Inc, 675 W Kendall St, Cambridge, MA 02142, USA., Bao G; Department of Bioengineering, Rice University, Houston, TX 77030, USA., Lagor WR; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2023 Jul 29. Date of Electronic Publication: 2023 Jul 29. |
| Publication Type: | Preprint; Journal Article |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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