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Unsupervised removal of systematic background noise from droplet-based single-cell experiments using CellBender.

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Title: Unsupervised removal of systematic background noise from droplet-based single-cell experiments using CellBender.
Authors: Fleming SJ; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA. sfleming@broadinstitute.org.; Precision Cardiology Laboratory (PCL), Broad Institute of MIT and Harvard, Cambridge, MA, USA. sfleming@broadinstitute.org., Chaffin MD; Precision Cardiology Laboratory (PCL), Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Arduini A; Precision Cardiology Laboratory (PCL), Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Bayer US, LLC, Cambridge, MA, USA., Akkad AD; Precision Cardiology Laboratory (PCL), Bayer US, LLC, Cambridge, MA, USA., Banks E; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Marioni JC; Wellcome Sanger Institute, Hinxton, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute, Cambridge, UK., Philippakis AA; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ellinor PT; Precision Cardiology Laboratory (PCL), Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Babadi M; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA. mehrtash@broadinstitute.org.; Precision Cardiology Laboratory (PCL), Broad Institute of MIT and Harvard, Cambridge, MA, USA. mehrtash@broadinstitute.org.
Source: Nature methods [Nat Methods] 2023 Sep; Vol. 20 (9), pp. 1323-1335. Date of Electronic Publication: 2023 Aug 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE
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  Data: Unsupervised removal of systematic background noise from droplet-based single-cell experiments using CellBender.
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  Data: <searchLink fieldCode="AU" term="%22Fleming+SJ%22">Fleming SJ</searchLink>; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA. sfleming@broadinstitute.org.; Precision Cardiology Laboratory (PCL), Broad Institute of MIT and Harvard, Cambridge, MA, USA. sfleming@broadinstitute.org.<br /><searchLink fieldCode="AU" term="%22Chaffin+MD%22">Chaffin MD</searchLink>; Precision Cardiology Laboratory (PCL), Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Arduini+A%22">Arduini A</searchLink>; Precision Cardiology Laboratory (PCL), Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Bayer US, LLC, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Akkad+AD%22">Akkad AD</searchLink>; Precision Cardiology Laboratory (PCL), Bayer US, LLC, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Banks+E%22">Banks E</searchLink>; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Marioni+JC%22">Marioni JC</searchLink>; Wellcome Sanger Institute, Hinxton, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Philippakis+AA%22">Philippakis AA</searchLink>; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ellinor+PT%22">Ellinor PT</searchLink>; Precision Cardiology Laboratory (PCL), Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Babadi+M%22">Babadi M</searchLink>; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA. mehrtash@broadinstitute.org.; Precision Cardiology Laboratory (PCL), Broad Institute of MIT and Harvard, Cambridge, MA, USA. mehrtash@broadinstitute.org.
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  Data: <searchLink fieldCode="JN" term="%22101215604%22">Nature methods</searchLink> [Nat Methods] 2023 Sep; Vol. 20 (9), pp. 1323-1335. <i>Date of Electronic Publication: </i>2023 Aug 07.
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