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Gemcitabine enhances pharmacokinetic exposure of the major components of Danggui Buxue Decoction in rat via the promotion of intestinal permeability and down-regulation of CYP3A for combination treatment of non-small cell lung cancer.

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Title: Gemcitabine enhances pharmacokinetic exposure of the major components of Danggui Buxue Decoction in rat via the promotion of intestinal permeability and down-regulation of CYP3A for combination treatment of non-small cell lung cancer.
Authors: Xu X; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China., Sun XY; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China., Chang M; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China., Hu ZL; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China., Cheng TT; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China., Hang TJ; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China., Song M; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China.
Source: Pharmaceutical biology [Pharm Biol] 2023 Dec; Vol. 61 (1), pp. 1298-1309.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9812552 Publication Model: Print Cited Medium: Internet ISSN: 1744-5116 (Electronic) Linking ISSN: 13880209 NLM ISO Abbreviation: Pharm Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Gemcitabine enhances pharmacokinetic exposure of the major components of Danggui Buxue Decoction in rat via the promotion of intestinal permeability and down-regulation of CYP3A for combination treatment of non-small cell lung cancer.
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  Data: <searchLink fieldCode="AU" term="%22Xu+X%22">Xu X</searchLink>; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Sun+XY%22">Sun XY</searchLink>; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Chang+M%22">Chang M</searchLink>; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Hu+ZL%22">Hu ZL</searchLink>; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Cheng+TT%22">Cheng TT</searchLink>; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Hang+TJ%22">Hang TJ</searchLink>; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Song+M%22">Song M</searchLink>; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9812552 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1744-5116 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213880209%22">13880209 </searchLink><i>NLM ISO Abbreviation: </i>Pharm Biol <i>Subsets: </i>MEDLINE
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        Value: 10.1080/13880209.2023.2246500
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        Text: English
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      – TitleFull: Gemcitabine enhances pharmacokinetic exposure of the major components of Danggui Buxue Decoction in rat via the promotion of intestinal permeability and down-regulation of CYP3A for combination treatment of non-small cell lung cancer.
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              Text: 2023 Dec
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