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Safety and immunogenicity of a recombinant oligomeric gp145 subtype C Env protein (gp145 C.6980) HIV vaccine candidate in healthy, HIV-1-uninfected adult participants in the US.

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Title: Safety and immunogenicity of a recombinant oligomeric gp145 subtype C Env protein (gp145 C.6980) HIV vaccine candidate in healthy, HIV-1-uninfected adult participants in the US.
Authors: Tieu HV; Laboratory of Infectious Disease Prevention, Lindsley F. Kimball Research Institute, New York Blood Center, USA; Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, USA., Karuna S; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Huang Y; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA; Department of Global Health, University of Washington, Seattle, WA, USA., Sobieszczyk ME; Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, USA., Zheng H; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Tomaras GD; Department of Global Health, University of Washington, Seattle, WA, USA., Montefiori DC; Department of Global Health, University of Washington, Seattle, WA, USA., Shen M; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., DeRosa S; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Cohen K; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Isaacs MB; Division of Refugee Health, Administration for Children and Families, Department of Health and Human Services, USA., Regenold S; Division of AIDS, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Heptinstall J; Department of Surgery, Duke University, Durham, NC, USA., Seaton KE; Department of Surgery, Duke University, Durham, NC, USA., Sawant S; Department of Surgery, Duke University, Durham, NC, USA., Furch B; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Pensiero M; Division of AIDS, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Corey L; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Bar KJ; Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: bark@pennmedicine.upenn.edu.
Corporate Authors: HVTN 122 Study Team
Source: Vaccine [Vaccine] 2023 Oct 06; Vol. 41 (42), pp. 6309-6317. Date of Electronic Publication: 2023 Sep 09.
Publication Type: Journal Article; Clinical Trial, Phase I; Randomized Controlled Trial; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8406899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2518 (Electronic) Linking ISSN: 0264410X NLM ISO Abbreviation: Vaccine Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Safety and immunogenicity of a recombinant oligomeric gp145 subtype C Env protein (gp145 C.6980) HIV vaccine candidate in healthy, HIV-1-uninfected adult participants in the US.
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  Data: <searchLink fieldCode="AU" term="%22Tieu+HV%22">Tieu HV</searchLink>; Laboratory of Infectious Disease Prevention, Lindsley F. Kimball Research Institute, New York Blood Center, USA; Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, USA.<br /><searchLink fieldCode="AU" term="%22Karuna+S%22">Karuna S</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA; Department of Global Health, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Sobieszczyk+ME%22">Sobieszczyk ME</searchLink>; Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, USA.<br /><searchLink fieldCode="AU" term="%22Zheng+H%22">Zheng H</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Tomaras+GD%22">Tomaras GD</searchLink>; Department of Global Health, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Montefiori+DC%22">Montefiori DC</searchLink>; Department of Global Health, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Shen+M%22">Shen M</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22DeRosa+S%22">DeRosa S</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Cohen+K%22">Cohen K</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Isaacs+MB%22">Isaacs MB</searchLink>; Division of Refugee Health, Administration for Children and Families, Department of Health and Human Services, USA.<br /><searchLink fieldCode="AU" term="%22Regenold+S%22">Regenold S</searchLink>; Division of AIDS, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Heptinstall+J%22">Heptinstall J</searchLink>; Department of Surgery, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Seaton+KE%22">Seaton KE</searchLink>; Department of Surgery, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Sawant+S%22">Sawant S</searchLink>; Department of Surgery, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Furch+B%22">Furch B</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Pensiero+M%22">Pensiero M</searchLink>; Division of AIDS, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Corey+L%22">Corey L</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Bar+KJ%22">Bar KJ</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: bark@pennmedicine.upenn.edu.
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  Data: <searchLink fieldCode="JN" term="%228406899%22">Vaccine</searchLink> [Vaccine] 2023 Oct 06; Vol. 41 (42), pp. 6309-6317. <i>Date of Electronic Publication: </i>2023 Sep 09.
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        Value: 10.1016/j.vaccine.2023.07.046
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