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SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells.

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Title: SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells.
Authors: Zhang L; Translational Biology and Molecular Medicine Graduate Program, Baylor College of Medicine, Houston, TX.; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX.; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX., Hsu JI; Translational Biology and Molecular Medicine Graduate Program, Baylor College of Medicine, Houston, TX.; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX.; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX., Braekeleer ED; Department of Haematology, Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge., Chen CW; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX.; Integrated Molecular and Biomedical Sciences Graduate Program, Baylor College of Medicine, Houston, TX., Patel TD; Texas Children's Hospital Department of Hematology/Oncology, Baylor College of Medicine, Houston, TX., Martell AG; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX., Guzman AG; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX., Wohlan K; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX., Waldvogel SM; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX.; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX.; Cancer and Cell Biology Graduate Program, Baylor College of Medicine, Houston, TX., Urya H; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX., Tovy A; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX., Callen E; Laboratory of Genome Integrity, National Cancer Institute, National Institute of Health, Bethesda, MD., Murdaugh R; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX.; Department of Neurosurgery, Baylor College of Medicine, Houston, TX., Richard R; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX.; Department of Neurosurgery, Baylor College of Medicine, Houston, TX., Jansen S; Donders Centre for Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands., Vissers L; Donders Centre for Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands., de Vries BBA; Donders Centre for Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands., Nussenzweig A; Cancer and Cell Biology Graduate Program, Baylor College of Medicine, Houston, TX., Huang S; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Department of Education, Innovation and Technology, Advanced Technology Cores., Coarfa C; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX., Anastas JN; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX.; Department of Neurosurgery, Baylor College of Medicine, Houston, TX., Takahashi K; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.; Department of Education, Innovation and Technology, Advanced Technology Cores., Vassiliou G; Department of Haematology, Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge., Goodell MA; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jan 17. Date of Electronic Publication: 2024 Jan 17.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Translational Biology and Molecular Medicine Graduate Program, Baylor College of Medicine, Houston, TX.; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX.; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Hsu+JI%22">Hsu JI</searchLink>; Translational Biology and Molecular Medicine Graduate Program, Baylor College of Medicine, Houston, TX.; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX.; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.<br /><searchLink fieldCode="AU" term="%22Braekeleer+ED%22">Braekeleer ED</searchLink>; Department of Haematology, Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge.<br /><searchLink fieldCode="AU" term="%22Chen+CW%22">Chen CW</searchLink>; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX.; Integrated Molecular and Biomedical Sciences Graduate Program, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Patel+TD%22">Patel TD</searchLink>; Texas Children's Hospital Department of Hematology/Oncology, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Martell+AG%22">Martell AG</searchLink>; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Guzman+AG%22">Guzman AG</searchLink>; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Wohlan+K%22">Wohlan K</searchLink>; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Waldvogel+SM%22">Waldvogel SM</searchLink>; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX.; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX.; Cancer and Cell Biology Graduate Program, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Urya+H%22">Urya H</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Tovy+A%22">Tovy A</searchLink>; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Callen+E%22">Callen E</searchLink>; Laboratory of Genome Integrity, National Cancer Institute, National Institute of Health, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Murdaugh+R%22">Murdaugh R</searchLink>; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX.; Department of Neurosurgery, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Richard+R%22">Richard R</searchLink>; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX.; Department of Neurosurgery, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Jansen+S%22">Jansen S</searchLink>; Donders Centre for Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Vissers+L%22">Vissers L</searchLink>; Donders Centre for Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Vries+BBA%22">de Vries BBA</searchLink>; Donders Centre for Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Nussenzweig+A%22">Nussenzweig A</searchLink>; Cancer and Cell Biology Graduate Program, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Huang+S%22">Huang S</searchLink>; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Department of Education, Innovation and Technology, Advanced Technology Cores.<br /><searchLink fieldCode="AU" term="%22Coarfa+C%22">Coarfa C</searchLink>; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Anastas+JN%22">Anastas JN</searchLink>; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX.; Department of Neurosurgery, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Takahashi+K%22">Takahashi K</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.; Department of Education, Innovation and Technology, Advanced Technology Cores.<br /><searchLink fieldCode="AU" term="%22Vassiliou+G%22">Vassiliou G</searchLink>; Department of Haematology, Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge.<br /><searchLink fieldCode="AU" term="%22Goodell+MA%22">Goodell MA</searchLink>; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.; Center for Cell and Gene Therapy, Houston, TX.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2024 Jan 17. <i>Date of Electronic Publication: </i>2024 Jan 17.
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