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Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker.

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Title: Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker.
Authors: Taylor MS; Department of Pathology, Mass General Brigham and Harvard Medical School, Boston, Massachusetts., Wu C; Department of Pathology, Mass General Brigham and Harvard Medical School, Boston, Massachusetts.; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts., Fridy PC; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, New York., Zhang SJ; Department of Pathology, Mass General Brigham and Harvard Medical School, Boston, Massachusetts.; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts., Senussi Y; Department of Pathology, Mass General Brigham and Harvard Medical School, Boston, Massachusetts.; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts., Wolters JC; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Cajuso T; Department of Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts., Cheng WC; Department of Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts., Heaps JD; Department of Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts., Miller BD; Department of Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts., Mori K; Department of Pathology, Mass General Brigham and Harvard Medical School, Boston, Massachusetts.; Healthcare Optics Research Laboratory, Canon U.S.A., Inc., Cambridge, Massachusetts., Cohen L; Department of Pathology, Mass General Brigham and Harvard Medical School, Boston, Massachusetts.; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts.; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts., Jiang H; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, New York., Molloy KR; Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, New York., Chait BT; Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, New York., Goggins MG; Johns Hopkins University School of Medicine, Baltimore, Maryland., Bhan I; Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Franses JW; Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Yang X; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts., Taplin ME; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts., Wang X; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts., Christiani DC; Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts., Johnson BE; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts., Meyerson M; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts., Uppaluri R; Department of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Egloff AM; Department of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Denault EN; Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Spring LM; Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Wang TL; Johns Hopkins University School of Medicine, Baltimore, Maryland., Shih IM; Johns Hopkins University School of Medicine, Baltimore, Maryland., Fairman JE; Johns Hopkins University School of Medicine, Baltimore, Maryland., Jung E; University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Arora KS; Department of Pathology, Mass General Brigham and Harvard Medical School, Boston, Massachusetts., Yilmaz OH; Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts., Cohen S; Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Sharova T; Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Chi G; Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Norden BL; Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Song Y; Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Nieman LT; Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Pappas L; Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Parikh AR; Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Strickland MR; Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Corcoran RB; Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Mustelin T; Division of Rheumatology, Department of Medicine, University of Washington, Seattle, Washington., Eng G; Department of Pathology, Mass General Brigham and Harvard Medical School, Boston, Massachusetts.; The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts., Yilmaz ÖH; Department of Pathology, Mass General Brigham and Harvard Medical School, Boston, Massachusetts.; The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts., Matulonis UA; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts., Chan AT; Clinical and Translational Epidemiology Unit and Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Skates SJ; MGH Biostatistics, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Rueda BR; Department of Obstetrics and Gynecology, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts., Drapkin R; University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Klempner SJ; Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Deshpande V; Department of Pathology, Mass General Brigham and Harvard Medical School, Boston, Massachusetts., Ting DT; Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Rout MP; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, New York., LaCava J; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, New York.; European Research Institute for the Biology of Ageing, University Medical Center Groningen, Groningen, the Netherlands., Walt DR; Department of Pathology, Mass General Brigham and Harvard Medical School, Boston, Massachusetts.; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts., Burns KH; Department of Pathology, Mass General Brigham and Harvard Medical School, Boston, Massachusetts.; Department of Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts.
Source: Cancer discovery [Cancer Discov] 2023 Dec 12; Vol. 13 (12), pp. 2532-2547.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
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            NameFull: Ting DT
      – PersonEntity:
          Name:
            NameFull: Rout MP
      – PersonEntity:
          Name:
            NameFull: LaCava J
      – PersonEntity:
          Name:
            NameFull: Walt DR
      – PersonEntity:
          Name:
            NameFull: Burns KH
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 12
              M: 12
              Text: 2023 Dec 12
              Type: published
              Y: 2023
          Identifiers:
            – Type: issn-electronic
              Value: 2159-8290
          Numbering:
            – Type: volume
              Value: 13
            – Type: issue
              Value: 12
          Titles:
            – TitleFull: Cancer discovery
              Type: main
ResultId 1