Single-cell multi-omics analysis of COVID-19 patients with pre-existing autoimmune diseases shows aberrant immune responses to infection.
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| Title: | Single-cell multi-omics analysis of COVID-19 patients with pre-existing autoimmune diseases shows aberrant immune responses to infection. |
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| Authors: | Barmada A; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Department of Medical Genetics, University of Cambridge, Cambridge, United Kingdom., Handfield LF; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom., Godoy-Tena G; Epigenetics and Immune Disease Group, Josep Carreras Research Institute (IJC), Barcelona, Spain., de la Calle-Fabregat C; Epigenetics and Immune Disease Group, Josep Carreras Research Institute (IJC), Barcelona, Spain., Ciudad L; Epigenetics and Immune Disease Group, Josep Carreras Research Institute (IJC), Barcelona, Spain., Arutyunyan A; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom., Andrés-León E; Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas (IPBLN-CSIC), Granada, Spain., Hoo R; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom., Porter T; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom., Oszlanczi A; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom., Richardson L; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom., Calero-Nieto FJ; Department of Haematology and Wellcome & MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom., Wilson NK; Department of Haematology and Wellcome & MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom., Marchese D; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Sancho-Serra C; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom., Carrillo J; IrsiCaixa AIDS Research Institute, Hospital Germans Trias i Pujol, Badalona, Spain., Presas-Rodríguez S; MS Unit, Department of Neurology, Germans Trias i Pujol University Hospital, Barcelona, Spain., Ramo-Tello C; MS Unit, Department of Neurology, Germans Trias i Pujol University Hospital, Barcelona, Spain., Ruiz-Sanmartin A; Department of Intensive Care, Hospital Universitari Vall d'Hebron, Shock, Organ Dysfunction and Resuscitation Research Group, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain., Ferrer R; Department of Intensive Care, Hospital Universitari Vall d'Hebron, Shock, Organ Dysfunction and Resuscitation Research Group, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain., Ruiz-Rodriguez JC; Department of Intensive Care, Hospital Universitari Vall d'Hebron, Shock, Organ Dysfunction and Resuscitation Research Group, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain., Martínez-Gallo M; Division of Immunology, Hospital Universitari Vall d'Hebron (HUVH), Vall d'Hebron Research Institute (VHIR), Barcelona, Spain., Munera-Campos M; Dermatology Service, Germans Trias i Pujol University Hospital, LCMN, Germans Trias i Pujol Research Institute (IGTP), Barcelona, Spain., Carrascosa JM; Dermatology Service, Germans Trias i Pujol University Hospital, LCMN, Germans Trias i Pujol Research Institute (IGTP), Barcelona, Spain., Göttgens B; Department of Haematology and Wellcome & MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom., Heyn H; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Prigmore E; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom., Casafont-Solé I; Department of Rheumatology, Germans Trias i Pujol University Hospital, LCMN, Germans Trias i Pujol Research Institute (IGTP), Barcelona, Spain.; Department of Infectious Diseases, Germans Trias i Pujol University Hospital, Barcelona, Spain., Solanich X; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain., Sánchez-Cerrillo I; Department of Immunology, Hospital Universitario La Princesa, IIS-IP, Madrid, Spain., González-Álvaro I; Rheumatology Service, Hospital Universitario La Princesa, IIS-IP, Madrid, Spain., Raimondo MG; Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany., Ramming A; Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany., Martin J; Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas (IPBLN-CSIC), Granada, Spain., Martínez-Cáceres E; Division of Immunology, Germans Trias i Pujol University Hospital, LCMN, Germans Trias i Pujol Research Institute (IGTP), Barcelona, Spain.; Department of Cell Biology, Physiology, and Immunology, Universitat Autònoma, Barcelona, Spain., Ballestar E; Epigenetics and Immune Disease Group, Josep Carreras Research Institute (IJC), Barcelona, Spain., Vento-Tormo R; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom., Rodríguez-Ubreva J; Epigenetics and Immune Disease Group, Josep Carreras Research Institute (IJC), Barcelona, Spain. |
| Source: | European journal of immunology [Eur J Immunol] 2024 Jan; Vol. 54 (1), pp. e2350633. Date of Electronic Publication: 2023 Oct 20. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 1273201 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4141 (Electronic) Linking ISSN: 00142980 NLM ISO Abbreviation: Eur J Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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