N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity.
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| Title: | N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity. |
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| Authors: | Varland S; Department of Biomedicine, University of Bergen, N-5021, Bergen, Norway. sylvia.varland@gmail.com.; Department of Biological Sciences, University of Bergen, N-5006, Bergen, Norway. sylvia.varland@gmail.com.; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada. sylvia.varland@gmail.com., Silva RD; Algarve Biomedical Center Research Institute, Universidade do Algarve, 8005-139, Faro, Portugal. rfdsilva@gmail.com.; Faculdade de Medicina e Ciências Biomédicas, Universidade do Algarve, 8005-139, Faro, Portugal. rfdsilva@gmail.com., Kjosås I; Department of Biomedicine, University of Bergen, N-5021, Bergen, Norway., Faustino A; Algarve Biomedical Center Research Institute, Universidade do Algarve, 8005-139, Faro, Portugal., Bogaert A; VIB-UGent Center for Medical Biotechnology, B-9052, Ghent, Belgium.; Department of Biomolecular Medicine, Ghent University, B-9052, Ghent, Belgium., Billmann M; Department of Computer Science and Engineering, University of Minnesota-Twin Cities, Minneapolis, MN, 55455, USA.; Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, D-53127, Bonn, Germany., Boukhatmi H; Institut de Génétique et Développement de Rennes (IGDR), Université de Rennes 1, CNRS, UMR6290, 35065, Rennes, France., Kellen B; Algarve Biomedical Center Research Institute, Universidade do Algarve, 8005-139, Faro, Portugal., Costanzo M; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada., Drazic A; Department of Biomedicine, University of Bergen, N-5021, Bergen, Norway., Osberg C; Department of Biomedicine, University of Bergen, N-5021, Bergen, Norway., Chan K; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada., Zhang X; Department of Computer Science and Engineering, University of Minnesota-Twin Cities, Minneapolis, MN, 55455, USA., Tong AHY; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada., Andreazza S; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, CB2 0XY, UK., Lee JJ; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, CB2 0XY, UK., Nedyalkova L; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada., Ušaj M; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada., Whitworth AJ; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, CB2 0XY, UK., Andrews BJ; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 3E1, Canada., Moffat J; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 3E1, Canada.; Program in Genetics & Genome Biology, The Hospital for Sick Children, Toronto, ON, M5G 1×8, Canada., Myers CL; Department of Computer Science and Engineering, University of Minnesota-Twin Cities, Minneapolis, MN, 55455, USA.; Bioinformatics and Computational Biology Graduate Program, University of Minnesota-Twin Cities, Minneapolis, MN, 55455, USA., Gevaert K; VIB-UGent Center for Medical Biotechnology, B-9052, Ghent, Belgium.; Department of Biomolecular Medicine, Ghent University, B-9052, Ghent, Belgium., Boone C; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 3E1, Canada.; RIKEN Centre for Sustainable Resource Science, Wako, Saitama, 351-0106, Japan., Martinho RG; Algarve Biomedical Center Research Institute, Universidade do Algarve, 8005-139, Faro, Portugal. rgmartinho@ua.pt.; Departmento de Ciências Médicas, Universidade de Aveiro, 3810-193, Aveiro, Portugal. rgmartinho@ua.pt.; iBiMED - Institute of Biomedicine, Universidade de Aveiro, 3810-193, Aveiro, Portugal. rgmartinho@ua.pt., Arnesen T; Department of Biomedicine, University of Bergen, N-5021, Bergen, Norway. thomas.arnesen@uib.no.; Department of Biological Sciences, University of Bergen, N-5006, Bergen, Norway. thomas.arnesen@uib.no.; Department of Surgery, Haukeland University Hospital, N-5021, Bergen, Norway. thomas.arnesen@uib.no. |
| Source: | Nature communications [Nat Commun] 2023 Oct 27; Vol. 14 (1), pp. 6774. Date of Electronic Publication: 2023 Oct 27. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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