Cooperative Armoring of CAR and TCR T Cells by T Cell-Restricted IL15 and IL21 Universally Enhances Solid Tumor Efficacy.

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Title: Cooperative Armoring of CAR and TCR T Cells by T Cell-Restricted IL15 and IL21 Universally Enhances Solid Tumor Efficacy.
Authors: Nguyen R; Pediatric Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Doubrovina E; Duncan and Nancy MacMillan Cancer Immunology and Metabolism Center of Excellence, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey., Mousset CM; Genitourinary Malignancy Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Jin BY; Genitourinary Malignancy Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Okada R; Pediatric Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Zhang X; Pediatric Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Clavel A; Duncan and Nancy MacMillan Cancer Immunology and Metabolism Center of Excellence, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey., Reyes-Gonzalez JM; Pediatric Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Dyomin V; Duncan and Nancy MacMillan Cancer Immunology and Metabolism Center of Excellence, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey., Diaz L; Duncan and Nancy MacMillan Cancer Immunology and Metabolism Center of Excellence, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey., Zhang L; Center for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Abbas S; Pediatric Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Sun M; Pediatric Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Hsieh CM; Laboratory of Molecular Biology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Ho M; Laboratory of Molecular Biology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Shern JF; Pediatric Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Gulley JL; Center for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Hinrichs CS; Duncan and Nancy MacMillan Cancer Immunology and Metabolism Center of Excellence, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Apr 15; Vol. 30 (8), pp. 1555-1566.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
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  Data: Cooperative Armoring of CAR and TCR T Cells by T Cell-Restricted IL15 and IL21 Universally Enhances Solid Tumor Efficacy.
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  Data: <searchLink fieldCode="AU" term="%22Nguyen+R%22">Nguyen R</searchLink>; Pediatric Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Doubrovina+E%22">Doubrovina E</searchLink>; Duncan and Nancy MacMillan Cancer Immunology and Metabolism Center of Excellence, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey.<br /><searchLink fieldCode="AU" term="%22Mousset+CM%22">Mousset CM</searchLink>; Genitourinary Malignancy Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Jin+BY%22">Jin BY</searchLink>; Genitourinary Malignancy Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Okada+R%22">Okada R</searchLink>; Pediatric Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Pediatric Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Clavel+A%22">Clavel A</searchLink>; Duncan and Nancy MacMillan Cancer Immunology and Metabolism Center of Excellence, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey.<br /><searchLink fieldCode="AU" term="%22Reyes-Gonzalez+JM%22">Reyes-Gonzalez JM</searchLink>; Pediatric Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Dyomin+V%22">Dyomin V</searchLink>; Duncan and Nancy MacMillan Cancer Immunology and Metabolism Center of Excellence, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey.<br /><searchLink fieldCode="AU" term="%22Diaz+L%22">Diaz L</searchLink>; Duncan and Nancy MacMillan Cancer Immunology and Metabolism Center of Excellence, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Center for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Abbas+S%22">Abbas S</searchLink>; Pediatric Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Sun+M%22">Sun M</searchLink>; Pediatric Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Hsieh+CM%22">Hsieh CM</searchLink>; Laboratory of Molecular Biology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Ho+M%22">Ho M</searchLink>; Laboratory of Molecular Biology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Shern+JF%22">Shern JF</searchLink>; Pediatric Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Gulley+JL%22">Gulley JL</searchLink>; Center for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Hinrichs+CS%22">Hinrichs CS</searchLink>; Duncan and Nancy MacMillan Cancer Immunology and Metabolism Center of Excellence, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey.
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