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IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer.

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Title: IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer.
Authors: Caronni N; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy. caronni.nicoletta@hsr.it., La Terza F; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy., Vittoria FM; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Barbiera G; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy., Mezzanzanica L; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Cuzzola V; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Barresi S; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy., Pellegatta M; IRCCS San Raffaele Scientific Institute, Milan, Italy., Canevazzi P; IRCCS San Raffaele Scientific Institute, Milan, Italy., Dunsmore G; INSERM U1015, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France., Leonardi C; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy., Montaldo E; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy., Lusito E; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy., Dugnani E; Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute, Milan, Italy., Citro A; Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute, Milan, Italy., Ng MSF; Singapore Immunology Network (SIgN), A*STAR, Singapore, Singapore., Schiavo Lena M; IRCCS San Raffaele Scientific Institute, Milan, Italy., Drago D; Center for Omics Sciences (COSR), IRCCS San Raffaele Scientific Institute, Milan, Italy., Andolfo A; Center for Omics Sciences (COSR), IRCCS San Raffaele Scientific Institute, Milan, Italy., Brugiapaglia S; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy., Scagliotti A; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy., Mortellaro A; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy., Corbo V; University of Verona, Verona, Italy., Liu Z; Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Mondino A; IRCCS San Raffaele Scientific Institute, Milan, Italy., Dellabona P; IRCCS San Raffaele Scientific Institute, Milan, Italy., Piemonti L; Vita-Salute San Raffaele University, Milan, Italy.; Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute, Milan, Italy., Taveggia C; IRCCS San Raffaele Scientific Institute, Milan, Italy., Doglioni C; Vita-Salute San Raffaele University, Milan, Italy.; IRCCS San Raffaele Scientific Institute, Milan, Italy., Cappello P; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy., Novelli F; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy., Iannacone M; Vita-Salute San Raffaele University, Milan, Italy.; IRCCS San Raffaele Scientific Institute, Milan, Italy., Ng LG; Shanghai Immune Therapy Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Ginhoux F; INSERM U1015, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France.; Singapore Immunology Network (SIgN), A*STAR, Singapore, Singapore.; Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Translational Immunology Institute, SingHealth/Duke-NUS Academic Medical Centre, Singapore, Singapore., Crippa S; Vita-Salute San Raffaele University, Milan, Italy.; Pancreas Translational and Clinical Research Center, IRCCS San Raffaele Scientific Institute, Milan, Italy., Falconi M; Vita-Salute San Raffaele University, Milan, Italy.; Pancreas Translational and Clinical Research Center, IRCCS San Raffaele Scientific Institute, Milan, Italy., Bonini C; Vita-Salute San Raffaele University, Milan, Italy.; IRCCS San Raffaele Scientific Institute, Milan, Italy., Naldini L; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Genua M; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy., Ostuni R; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy. ostuni.renato@hsr.it.; Vita-Salute San Raffaele University, Milan, Italy. ostuni.renato@hsr.it.
Source: Nature [Nature] 2023 Nov; Vol. 623 (7986), pp. 415-422. Date of Electronic Publication: 2023 Nov 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: IL-1β<superscript>+</superscript> macrophages fuel pathogenic inflammation in pancreatic cancer.
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  Data: <searchLink fieldCode="AU" term="%22Caronni+N%22">Caronni N</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy. caronni.nicoletta@hsr.it.<br /><searchLink fieldCode="AU" term="%22La+Terza+F%22">La Terza F</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Vittoria+FM%22">Vittoria FM</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Barbiera+G%22">Barbiera G</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mezzanzanica+L%22">Mezzanzanica L</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cuzzola+V%22">Cuzzola V</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Barresi+S%22">Barresi S</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pellegatta+M%22">Pellegatta M</searchLink>; IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Canevazzi+P%22">Canevazzi P</searchLink>; IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Dunsmore+G%22">Dunsmore G</searchLink>; INSERM U1015, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Leonardi+C%22">Leonardi C</searchLink>; 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University of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Mondino+A%22">Mondino A</searchLink>; IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Dellabona+P%22">Dellabona P</searchLink>; IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Piemonti+L%22">Piemonti L</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.; Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Taveggia+C%22">Taveggia C</searchLink>; IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Doglioni+C%22">Doglioni C</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.; IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cappello+P%22">Cappello P</searchLink>; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Novelli+F%22">Novelli F</searchLink>; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Iannacone+M%22">Iannacone M</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.; IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ng+LG%22">Ng LG</searchLink>; Shanghai Immune Therapy Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Ginhoux+F%22">Ginhoux F</searchLink>; INSERM U1015, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France.; Singapore Immunology Network (SIgN), A*STAR, Singapore, Singapore.; Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Translational Immunology Institute, SingHealth/Duke-NUS Academic Medical Centre, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Crippa+S%22">Crippa S</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.; Pancreas Translational and Clinical Research Center, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Falconi+M%22">Falconi M</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.; Pancreas Translational and Clinical Research Center, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bonini+C%22">Bonini C</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.; IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Naldini+L%22">Naldini L</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Genua+M%22">Genua M</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ostuni+R%22">Ostuni R</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy. ostuni.renato@hsr.it.; Vita-Salute San Raffaele University, Milan, Italy. ostuni.renato@hsr.it.
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