A drug-like molecule engages nuclear hormone receptor DAF-12/FXR to regulate mitophagy and extend lifespan. - Chamoli M; Rane A; Foulger A; Chinta SJ; Shahmirzadi AA; Kumsta C; Nambiar DK; Hall D; Holcom A; Angeli S; Schmidt M; Pitteri S; et al. (Nature aging, 2023)