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Development of a Peripherally Restricted 5-HT2B Partial Agonist for Treatment of Pulmonary Arterial Hypertension.

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Title: Development of a Peripherally Restricted 5-HT2B Partial Agonist for Treatment of Pulmonary Arterial Hypertension.
Authors: Valentine MS; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA., Bender AM; Warren Center for Neuroscience Drug Discovery, Department of Pharmacology and Chemistry, Vanderbilt University, Nashville, Tennessee, USA., Shay S; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Paffenroth KC; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA., Gladson S; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Dickerson JW; Warren Center for Neuroscience Drug Discovery, Department of Pharmacology and Chemistry, Vanderbilt University, Nashville, Tennessee, USA., Watson KJ; Warren Center for Neuroscience Drug Discovery, Department of Pharmacology and Chemistry, Vanderbilt University, Nashville, Tennessee, USA., Kapolka NJ; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Boutaud O; Warren Center for Neuroscience Drug Discovery, Department of Pharmacology and Chemistry, Vanderbilt University, Nashville, Tennessee, USA., Rook JM; Warren Center for Neuroscience Drug Discovery, Department of Pharmacology and Chemistry, Vanderbilt University, Nashville, Tennessee, USA., Blackwell TS; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Roth BL; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Harrison FE; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Austin ED; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., West JD; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Lindsley CW; Warren Center for Neuroscience Drug Discovery, Department of Pharmacology and Chemistry, Vanderbilt University, Nashville, Tennessee, USA., Merryman WD; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA.
Source: JACC. Basic to translational science [JACC Basic Transl Sci] 2023 Sep 13; Vol. 8 (10), pp. 1379-1388. Date of Electronic Publication: 2023 Sep 13 (Print Publication: 2023).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier on behalf of the American College of Cardiology Foundation Country of Publication: United States NLM ID: 101677259 Publication Model: eCollection Cited Medium: Internet ISSN: 2452-302X (Electronic) Linking ISSN: 2452302X NLM ISO Abbreviation: JACC Basic Transl Sci Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Development of a Peripherally Restricted 5-HT<subscript>2B</subscript> Partial Agonist for Treatment of Pulmonary Arterial Hypertension.
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  Data: <searchLink fieldCode="AU" term="%22Valentine+MS%22">Valentine MS</searchLink>; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Bender+AM%22">Bender AM</searchLink>; Warren Center for Neuroscience Drug Discovery, Department of Pharmacology and Chemistry, Vanderbilt University, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Shay+S%22">Shay S</searchLink>; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Paffenroth+KC%22">Paffenroth KC</searchLink>; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Gladson+S%22">Gladson S</searchLink>; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Dickerson+JW%22">Dickerson JW</searchLink>; Warren Center for Neuroscience Drug Discovery, Department of Pharmacology and Chemistry, Vanderbilt University, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Watson+KJ%22">Watson KJ</searchLink>; Warren Center for Neuroscience Drug Discovery, Department of Pharmacology and Chemistry, Vanderbilt University, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Kapolka+NJ%22">Kapolka NJ</searchLink>; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Boutaud+O%22">Boutaud O</searchLink>; Warren Center for Neuroscience Drug Discovery, Department of Pharmacology and Chemistry, Vanderbilt University, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Rook+JM%22">Rook JM</searchLink>; Warren Center for Neuroscience Drug Discovery, Department of Pharmacology and Chemistry, Vanderbilt University, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Blackwell+TS%22">Blackwell TS</searchLink>; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Roth+BL%22">Roth BL</searchLink>; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Harrison+FE%22">Harrison FE</searchLink>; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Austin+ED%22">Austin ED</searchLink>; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22West+JD%22">West JD</searchLink>; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Lindsley+CW%22">Lindsley CW</searchLink>; Warren Center for Neuroscience Drug Discovery, Department of Pharmacology and Chemistry, Vanderbilt University, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Merryman+WD%22">Merryman WD</searchLink>; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA.
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  Data: <searchLink fieldCode="JN" term="%22101677259%22">JACC. Basic to translational science</searchLink> [JACC Basic Transl Sci] 2023 Sep 13; Vol. 8 (10), pp. 1379-1388. <i>Date of Electronic Publication: </i>2023 Sep 13 (<i>Print Publication: </i>2023).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+on+behalf+of+the+American+College+of+Cardiology+Foundation%22">Elsevier on behalf of the American College of Cardiology Foundation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101677259 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2452-302X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222452302X%22">2452302X </searchLink><i>NLM ISO Abbreviation: </i>JACC Basic Transl Sci <i>Subsets: </i>PubMed not MEDLINE
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