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Interpretation of in vitro concentration-response data for risk assessment and regulatory decision-making: Report from the 2022 IWGT quantitative analysis expert working group meeting.

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Title: Interpretation of in vitro concentration-response data for risk assessment and regulatory decision-making: Report from the 2022 IWGT quantitative analysis expert working group meeting.
Authors: Beal MA; Bureau of Chemical Safety, Health Products and Food Branch, Health Canada, Ottawa, Ontario, Canada., Chen G; Centre for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment (RIVM), Utrecht, the Netherlands., Dearfield KL; Retired from US Environmental Protection Agency and US Department of Agriculture, Washington, DC, USA., Gi M; Department of Environmental Risk Assessment, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan., Gollapudi B; Toxicology Consultant, Midland, Michigan, USA., Heflich RH; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas, USA., Horibata K; Division of Genetics and Mutagenesis, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan., Long AS; Existing Substances Risk Assessment Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada., Lovell DP; St George's Medical School, University of London, London, UK., Parsons BL; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas, USA., Pfuhler S; Global Product Stewardship - Human Safety, Procter & Gamble, Cincinnati, Ohio, USA., Wills J; Genetic Toxicology and Photosafety, GSK Research & Development, Stevenage, UK., Zeller A; Pharmaceutical Sciences, pRED Innovation Center Basel, Hoffmann-La Roche Ltd, Basel, Switzerland., Johnson G; Swansea University Medical School, Swansea University, Swansea, UK., White PA; Environmental Health Science and Research Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada.
Source: Environmental and molecular mutagenesis [Environ Mol Mutagen] 2025 Dec; Vol. 66 Suppl 2, pp. 101-120. Date of Electronic Publication: 2024 Feb 01.
Publication Type: Journal Article; Review
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8800109 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2280 (Electronic) Linking ISSN: 08936692 NLM ISO Abbreviation: Environ Mol Mutagen Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Interpretation of in vitro concentration-response data for risk assessment and regulatory decision-making: Report from the 2022 IWGT quantitative analysis expert working group meeting.
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  Data: <searchLink fieldCode="AU" term="%22Beal+MA%22">Beal MA</searchLink>; Bureau of Chemical Safety, Health Products and Food Branch, Health Canada, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Chen+G%22">Chen G</searchLink>; Centre for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment (RIVM), Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Dearfield+KL%22">Dearfield KL</searchLink>; Retired from US Environmental Protection Agency and US Department of Agriculture, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Gi+M%22">Gi M</searchLink>; Department of Environmental Risk Assessment, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Gollapudi+B%22">Gollapudi B</searchLink>; Toxicology Consultant, Midland, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Heflich+RH%22">Heflich RH</searchLink>; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas, USA.<br /><searchLink fieldCode="AU" term="%22Horibata+K%22">Horibata K</searchLink>; Division of Genetics and Mutagenesis, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Long+AS%22">Long AS</searchLink>; Existing Substances Risk Assessment Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Lovell+DP%22">Lovell DP</searchLink>; St George's Medical School, University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Parsons+BL%22">Parsons BL</searchLink>; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas, USA.<br /><searchLink fieldCode="AU" term="%22Pfuhler+S%22">Pfuhler S</searchLink>; Global Product Stewardship - Human Safety, Procter & Gamble, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Wills+J%22">Wills J</searchLink>; Genetic Toxicology and Photosafety, GSK Research & Development, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Zeller+A%22">Zeller A</searchLink>; Pharmaceutical Sciences, pRED Innovation Center Basel, Hoffmann-La Roche Ltd, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Johnson+G%22">Johnson G</searchLink>; Swansea University Medical School, Swansea University, Swansea, UK.<br /><searchLink fieldCode="AU" term="%22White+PA%22">White PA</searchLink>; Environmental Health Science and Research Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada.
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              Text: 2025 Dec
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              Y: 2025
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              Value: 66 Suppl 2
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