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Genomic and Immunophenotypic Landscape of Acquired Resistance to PD-(L)1 Blockade in Non-Small-Cell Lung Cancer.

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Title: Genomic and Immunophenotypic Landscape of Acquired Resistance to PD-(L)1 Blockade in Non-Small-Cell Lung Cancer.
Authors: Ricciuti B; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Lamberti G; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Puchala SR; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA., Mahadevan NR; Department of Pathology, Brigham and Women's Hospital, Boston, MA., Lin JR; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA., Alessi JV; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Chowdhury A; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA., Li YY; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA.; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA., Wang X; Harvard School of Public Health, Boston, MA., Spurr L; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA., Pecci F; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Di Federico A; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Venkatraman D; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Barrichello AP; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Gandhi M; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Vaz VR; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Pangilinan AJ; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Haradon D; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Lee E; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Gupta H; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA., Pfaff KL; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA., Welsh EL; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA., Nishino M; Department of Radiology, Brigham and Women's Hospital, Boston, MA., Cherniack AD; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA., Johnson BE; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Weirather JL; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA., Dryg ID; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA., Rodig SJ; Department of Pathology, Brigham and Women's Hospital, Boston, MA.; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA., Sholl LM; Department of Pathology, Brigham and Women's Hospital, Boston, MA., Sorger P; Department of Pathology, Brigham and Women's Hospital, Boston, MA.; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA., Santagata S; Department of Pathology, Brigham and Women's Hospital, Boston, MA.; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA., Umeton R; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA., Awad MM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA.
Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2024 Apr 10; Vol. 42 (11), pp. 1311-1321. Date of Electronic Publication: 2024 Jan 11.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Genomic and Immunophenotypic Landscape of Acquired Resistance to PD-(L)1 Blockade in Non-Small-Cell Lung Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Ricciuti+B%22">Ricciuti B</searchLink>; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Lamberti+G%22">Lamberti G</searchLink>; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Puchala+SR%22">Puchala SR</searchLink>; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Mahadevan+NR%22">Mahadevan NR</searchLink>; Department of Pathology, Brigham and Women's Hospital, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Lin+JR%22">Lin JR</searchLink>; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Alessi+JV%22">Alessi JV</searchLink>; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Chowdhury+A%22">Chowdhury A</searchLink>; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Li+YY%22">Li YY</searchLink>; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA.; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Harvard School of Public Health, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Spurr+L%22">Spurr L</searchLink>; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Pecci+F%22">Pecci F</searchLink>; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Di+Federico+A%22">Di Federico A</searchLink>; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Venkatraman+D%22">Venkatraman D</searchLink>; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Barrichello+AP%22">Barrichello AP</searchLink>; 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Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Welsh+EL%22">Welsh EL</searchLink>; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Nishino+M%22">Nishino M</searchLink>; Department of Radiology, Brigham and Women's Hospital, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Cherniack+AD%22">Cherniack AD</searchLink>; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Johnson+BE%22">Johnson BE</searchLink>; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Weirather+JL%22">Weirather JL</searchLink>; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Dryg+ID%22">Dryg ID</searchLink>; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Rodig+SJ%22">Rodig SJ</searchLink>; Department of Pathology, Brigham and Women's Hospital, Boston, MA.; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Sholl+LM%22">Sholl LM</searchLink>; Department of Pathology, Brigham and Women's Hospital, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Sorger+P%22">Sorger P</searchLink>; Department of Pathology, Brigham and Women's Hospital, Boston, MA.; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Santagata+S%22">Santagata S</searchLink>; Department of Pathology, Brigham and Women's Hospital, Boston, MA.; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Umeton+R%22">Umeton R</searchLink>; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Awad+MM%22">Awad MM</searchLink>; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA.
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