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Glioma-Induced Alterations in Excitatory Neurons are Reversed by mTOR Inhibition.

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Title: Glioma-Induced Alterations in Excitatory Neurons are Reversed by mTOR Inhibition.
Authors: Goldberg AR; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Dovas A; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Torres D; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Sharma SD; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032., Mela A; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Merricks EM; Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA., Olabarria M; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Shokooh LA; Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA., Zhao HT; Laboratory for Functional Optical Imaging, Zuckerman Mind Brain Behavior Institute, Departments of Biomedical Engineering and Radiology, Columbia University, New York, NY 10027, USA., Kotidis C; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA., Calvaresi P; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Viswanathan A; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Banu MA; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA., Razavilar A; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Sudhakar TD; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Saxena A; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Chokran C; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Humala N; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA., Mahajan A; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA., Xu W; Laboratory for Functional Optical Imaging, Zuckerman Mind Brain Behavior Institute, Departments of Biomedical Engineering and Radiology, Columbia University, New York, NY 10027, USA., Metz JB; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032., Chen C; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Bushong EA; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, USA., Boassa D; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, USA., Ellisman MH; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, USA., Hillman EMC; Laboratory for Functional Optical Imaging, Zuckerman Mind Brain Behavior Institute, Departments of Biomedical Engineering and Radiology, Columbia University, New York, NY 10027, USA., McKhann GM 2nd; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA., Gill BJA; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA., Rosenfeld SS; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL 32224, USA., Schevon CA; Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA., Bruce JN; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA., Sims PA; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032.; Sulzberger Columbia Genome Center, Columbia University Irving Medical Center, New York, NY, 10032.; Department of Biochemistry & Molecular Biophysics, Columbia University Irving Medical Center, New York, NY, 10032., Peterka DS; Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA.; Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA., Canoll P; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA.; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jan 21. Date of Electronic Publication: 2024 Jan 21.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Glioma-Induced Alterations in Excitatory Neurons are Reversed by mTOR Inhibition.
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Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Olabarria+M%22">Olabarria M</searchLink>; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Shokooh+LA%22">Shokooh LA</searchLink>; Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+HT%22">Zhao HT</searchLink>; Laboratory for Functional Optical Imaging, Zuckerman Mind Brain Behavior Institute, Departments of Biomedical Engineering and Radiology, Columbia University, New York, NY 10027, USA.<br /><searchLink fieldCode="AU" term="%22Kotidis+C%22">Kotidis C</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Calvaresi+P%22">Calvaresi P</searchLink>; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Viswanathan+A%22">Viswanathan A</searchLink>; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Banu+MA%22">Banu MA</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Razavilar+A%22">Razavilar A</searchLink>; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Sudhakar+TD%22">Sudhakar TD</searchLink>; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Saxena+A%22">Saxena A</searchLink>; 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Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032.<br /><searchLink fieldCode="AU" term="%22Chen+C%22">Chen C</searchLink>; Department of Pathology and Cell Biology, Irving Cancer Research Center, Columbia University Irving Medical Center, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Bushong+EA%22">Bushong EA</searchLink>; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, USA.<br /><searchLink fieldCode="AU" term="%22Boassa+D%22">Boassa D</searchLink>; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, USA.<br /><searchLink fieldCode="AU" term="%22Ellisman+MH%22">Ellisman MH</searchLink>; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, USA.<br /><searchLink fieldCode="AU" term="%22Hillman+EMC%22">Hillman EMC</searchLink>; Laboratory for Functional Optical Imaging, Zuckerman Mind Brain Behavior Institute, Departments of Biomedical Engineering and Radiology, Columbia University, New York, NY 10027, USA.<br /><searchLink fieldCode="AU" term="%22McKhann+GM+2nd%22">McKhann GM 2nd</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Gill+BJA%22">Gill BJA</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Rosenfeld+SS%22">Rosenfeld SS</searchLink>; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Schevon+CA%22">Schevon CA</searchLink>; Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Bruce+JN%22">Bruce JN</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Sims+PA%22">Sims PA</searchLink>; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032.; Sulzberger Columbia Genome Center, Columbia University Irving Medical Center, New York, NY, 10032.; Department of Biochemistry & Molecular Biophysics, Columbia University Irving Medical Center, New York, NY, 10032.<br /><searchLink fieldCode="AU" term="%22Peterka+DS%22">Peterka DS</searchLink>; Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA.; Mortimer B. 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