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Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19.

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Title: Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19.
Authors: Radke J; Institute of Pathology, Universitätsmedizin Greifswald, Greifswald, Germany. josefine.radke@med.uni-greifswald.de.; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany. josefine.radke@med.uni-greifswald.de., Meinhardt J; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Aschman T; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Chua RL; Center of Digital Health, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany., Farztdinov V; Core Facility High Throughput Mass Spectrometry, Charité - Universitätsmedizin Berlin, Berlin, Germany., Lukassen S; Center of Digital Health, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany., Ten FW; Center of Digital Health, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany., Friebel E; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Ishaque N; Center of Digital Health, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany., Franz J; Department of Neuropathology, University Medical Center Göttingen, Göttingen, Germany., Huhle VH; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Mothes R; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Peters K; Institute of Pathology, Universitätsmedizin Greifswald, Greifswald, Germany., Thomas C; Department of Neuropathology, University Medical Center Göttingen, Göttingen, Germany., Schneeberger S; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Schumann E; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Kawelke L; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Jünger J; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Horst V; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Streit S; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., von Manitius R; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Körtvélyessy P; Department of Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Vielhaber S; Department of Neurology, Otto von Guerike University Magdeburg, Magdeburg, Germany., Reinhold D; Institute of Molecular and Clinical Immunology, Otto von Guerike University Magdeburg, Magdeburg, Germany., Hauser AE; Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Immune Dynamics, Deutsches Rheuma-Forschungszentrum, a Leibniz Institute, Berlin, Germany., Osterloh A; Department of Pathology, University Medical Center Ulm, Ulm, Germany., Enghard P; Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany., Ihlow J; Department of Pathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Elezkurtaj S; Department of Pathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Horst D; Department of Pathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Kurth F; Department of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany., Müller MA; Institute of Virology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Gassen NC; Department of Psychiatry and Psychotherapy, University Hospital Bonn, Bonn, Germany., Melchert J; Institute of Virology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Jechow K; Center of Digital Health, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany., Timmermann B; Max Planck Institute for Molecular Genetics, Berlin, Germany., Fernandez-Zapata C; Experimental and Clinical Research Center, a cooperation between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité - Universitätsmedizin Berlin, Berlin, Germany., Böttcher C; Experimental and Clinical Research Center, a cooperation between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité - Universitätsmedizin Berlin, Berlin, Germany., Stenzel W; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Krüger E; Institute of Medical Biochemistry and Molecular Biology, Universitätsmedizin Greifswald, Greifswald, Germany., Landthaler M; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; Institut für Biologie, Humboldt Universität, Berlin, Germany., Wyler E; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany., Corman V; Department of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.; German Centre for Infection Research (DZIF), associated partner, Berlin, Germany., Stadelmann C; Department of Neuropathology, University Medical Center Göttingen, Göttingen, Germany., Ralser M; Core Facility High Throughput Mass Spectrometry, Charité - Universitätsmedizin Berlin, Berlin, Germany., Eils R; Center of Digital Health, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany., Heppner FL; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Cluster of Excellence NeuroCure, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Charité - Universitätsmedizin Berlin, Berlin, Germany., Mülleder M; Core Facility High Throughput Mass Spectrometry, Charité - Universitätsmedizin Berlin, Berlin, Germany., Conrad C; Center of Digital Health, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany., Radbruch H; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany. Helena.radbruch@charite.de.
Source: Nature neuroscience [Nat Neurosci] 2024 Mar; Vol. 27 (3), pp. 409-420. Date of Electronic Publication: 2024 Feb 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE
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  Data: Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19.
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  Data: <searchLink fieldCode="AU" term="%22Radke+J%22">Radke J</searchLink>; Institute of Pathology, Universitätsmedizin Greifswald, Greifswald, Germany. josefine.radke@med.uni-greifswald.de.; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany. josefine.radke@med.uni-greifswald.de.<br /><searchLink fieldCode="AU" term="%22Meinhardt+J%22">Meinhardt J</searchLink>; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Aschman+T%22">Aschman T</searchLink>; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Chua+RL%22">Chua RL</searchLink>; Center of Digital Health, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Farztdinov+V%22">Farztdinov V</searchLink>; Core Facility High Throughput Mass Spectrometry, Charité - Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Lukassen+S%22">Lukassen S</searchLink>; 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