Phase I dose-escalation study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of an inhaled recombinant human ACE2.

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Title: Phase I dose-escalation study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of an inhaled recombinant human ACE2.
Authors: Bauer M; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.; M. Bauer and M. Zeitlinger contributed equally to this article as lead authors and supervised the work., Jorda A; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria., Al-Jalali V; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria., Wölfl-Duchek M; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria., Bergmann F; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria., Nussbaumer-Pröll A; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria., Steindl A; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.; Division of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria., Gugenberger R; APEIRON Respiratory Therapies GmbH, Vienna, Austria., Bischof S; APEIRON Respiratory Therapies GmbH, Vienna, Austria., Wimmer D; APEIRON Respiratory Therapies GmbH, Vienna, Austria., Idzko M; Department of Pulmonology, Medical University of Vienna, Vienna, Austria., Zeitlinger M; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.; M. Bauer and M. Zeitlinger contributed equally to this article as lead authors and supervised the work.
Source: ERJ open research [ERJ Open Res] 2024 Feb 19; Vol. 10 (1). Date of Electronic Publication: 2024 Feb 19 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: European Respiratory Society Country of Publication: England NLM ID: 101671641 Publication Model: eCollection Cited Medium: Print ISSN: 2312-0541 (Print) Linking ISSN: 23120541 NLM ISO Abbreviation: ERJ Open Res Subsets: PubMed not MEDLINE
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  Data: Phase I dose-escalation study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of an inhaled recombinant human ACE2.
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  Data: <searchLink fieldCode="AU" term="%22Bauer+M%22">Bauer M</searchLink>; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.; M. Bauer and M. Zeitlinger contributed equally to this article as lead authors and supervised the work.<br /><searchLink fieldCode="AU" term="%22Jorda+A%22">Jorda A</searchLink>; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Al-Jalali+V%22">Al-Jalali V</searchLink>; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Wölfl-Duchek+M%22">Wölfl-Duchek M</searchLink>; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Bergmann+F%22">Bergmann F</searchLink>; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Nussbaumer-Pröll+A%22">Nussbaumer-Pröll A</searchLink>; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Steindl+A%22">Steindl A</searchLink>; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.; Division of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Gugenberger+R%22">Gugenberger R</searchLink>; APEIRON Respiratory Therapies GmbH, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Bischof+S%22">Bischof S</searchLink>; APEIRON Respiratory Therapies GmbH, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Wimmer+D%22">Wimmer D</searchLink>; APEIRON Respiratory Therapies GmbH, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Idzko+M%22">Idzko M</searchLink>; Department of Pulmonology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Zeitlinger+M%22">Zeitlinger M</searchLink>; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.; M. Bauer and M. Zeitlinger contributed equally to this article as lead authors and supervised the work.
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  Data: <searchLink fieldCode="JN" term="%22101671641%22">ERJ open research</searchLink> [ERJ Open Res] 2024 Feb 19; Vol. 10 (1). <i>Date of Electronic Publication: </i>2024 Feb 19 (<i>Print Publication: </i>2024).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22European+Respiratory+Society%22">European Respiratory Society </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101671641 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2312-0541 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223120541%22">23120541 </searchLink><i>NLM ISO Abbreviation: </i>ERJ Open Res <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2024 Feb 19
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