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QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration.

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Title: QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration.
Authors: Advani J; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD, USA., Mehta PA; Ocular Genomics Institute, Department of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hamel AR; Ocular Genomics Institute, Department of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Mehrotra S; Ocular Genomics Institute, Department of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kiel C; Institute of Human Genetics, University of Regensburg, Regensburg, Germany., Strunz T; Institute of Human Genetics, University of Regensburg, Regensburg, Germany., Corso-Díaz X; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD, USA., Kwicklis M; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD, USA., van Asten F; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD, USA., Ratnapriya R; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD, USA., Chew EY; Division of Epidemiology and Clinical Applications, Clinical Trials Branch, National Eye Institute, National Institutes of Health, Bethesda, MD, USA., Hernandez DG; Laboratory of Neurogenetics, National Institute of Aging, National Institutes of Health, Bethesda, MD, USA., Montezuma SR; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA., Ferrington DA; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.; Doheny Eye Institute, Pasadena, CA, USA., Weber BHF; Institute of Human Genetics, University of Regensburg, Regensburg, Germany.; Institute of Clinical Human Genetics, University Hospital Regensburg, Regensburg, Germany., Segrè AV; Ocular Genomics Institute, Department of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA. ayellet_segre@meei.harvard.edu.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA. ayellet_segre@meei.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. ayellet_segre@meei.harvard.edu., Swaroop A; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD, USA. swaroopa@nei.nih.gov.
Source: Nature communications [Nat Commun] 2024 Mar 04; Vol. 15 (1), pp. 1972. Date of Electronic Publication: 2024 Mar 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration.
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  Data: <searchLink fieldCode="AU" term="%22Advani+J%22">Advani J</searchLink>; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Mehta+PA%22">Mehta PA</searchLink>; Ocular Genomics Institute, Department of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hamel+AR%22">Hamel AR</searchLink>; Ocular Genomics Institute, Department of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mehrotra+S%22">Mehrotra S</searchLink>; Ocular Genomics Institute, Department of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kiel+C%22">Kiel C</searchLink>; Institute of Human Genetics, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Strunz+T%22">Strunz T</searchLink>; Institute of Human Genetics, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Corso-Díaz+X%22">Corso-Díaz X</searchLink>; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kwicklis+M%22">Kwicklis M</searchLink>; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22van+Asten+F%22">van Asten F</searchLink>; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ratnapriya+R%22">Ratnapriya R</searchLink>; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Chew+EY%22">Chew EY</searchLink>; Division of Epidemiology and Clinical Applications, Clinical Trials Branch, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Hernandez+DG%22">Hernandez DG</searchLink>; Laboratory of Neurogenetics, National Institute of Aging, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Montezuma+SR%22">Montezuma SR</searchLink>; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Ferrington+DA%22">Ferrington DA</searchLink>; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.; Doheny Eye Institute, Pasadena, CA, USA.<br /><searchLink fieldCode="AU" term="%22Weber+BHF%22">Weber BHF</searchLink>; Institute of Human Genetics, University of Regensburg, Regensburg, Germany.; Institute of Clinical Human Genetics, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Segrè+AV%22">Segrè AV</searchLink>; Ocular Genomics Institute, Department of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA. ayellet_segre@meei.harvard.edu.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA. ayellet_segre@meei.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. ayellet_segre@meei.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Swaroop+A%22">Swaroop A</searchLink>; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD, USA. swaroopa@nei.nih.gov.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2024 Mar 04; Vol. 15 (1), pp. 1972. <i>Date of Electronic Publication: </i>2024 Mar 04.
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