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Ageing impairs the regenerative capacity of regulatory T cells in mouse central nervous system remyelination.

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Title: Ageing impairs the regenerative capacity of regulatory T cells in mouse central nervous system remyelination.
Authors: de la Fuente AG; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK. guzman_ale@isabial.es.; Institute for Health and Biomedical Sciences of Alicante (ISABIAL), Alicante, 03010, Spain. guzman_ale@isabial.es.; Instituto de Neurosciencias CSIC-UMH, San Juan de Alicante, Alicante, 03550, Spain. guzman_ale@isabial.es., Dittmer M; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK., Heesbeen EJ; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.; Division of Pharmacology, Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., de la Vega Gallardo N; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK., White JA; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK., Young A; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK., McColgan T; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK., Dashwood A; Department of Pathology, University of Cambridge, CB2 1QP, Cambridge, UK.; Babraham Institute, CB22 3AT, Cambridge, UK., Mayne K; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK., Cabeza-Fernández S; Institute for Health and Biomedical Sciences of Alicante (ISABIAL), Alicante, 03010, Spain.; Instituto de Neurosciencias CSIC-UMH, San Juan de Alicante, Alicante, 03550, Spain., Falconer J; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.; CRUK Beatson Institute, G61 1BD, Glasgow, UK., Rodriguez-Baena FJ; Instituto de Neurosciencias CSIC-UMH, San Juan de Alicante, Alicante, 03550, Spain., McMurran CE; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden., Inayatullah M; Institute of Molecular Medicine, University of Southern Denmark, 5000, Odense, Denmark.; Danish Institute for Advanced Study (DIAS), 5230, Odense, Denmark., Rawji KS; Altos Labs - Cambridge Institute of Science, Granta Park, Cambridge, CB21 6GP, UK., Franklin RJM; Altos Labs - Cambridge Institute of Science, Granta Park, Cambridge, CB21 6GP, UK., Dooley J; Department of Pathology, University of Cambridge, CB2 1QP, Cambridge, UK., Liston A; Department of Pathology, University of Cambridge, CB2 1QP, Cambridge, UK., Ingram RJ; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK., Tiwari VK; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.; Institute of Molecular Medicine, University of Southern Denmark, 5000, Odense, Denmark.; Danish Institute for Advanced Study (DIAS), 5230, Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, 5000, Odense, Denmark., Penalva R; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK., Dombrowski Y; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK., Fitzgerald DC; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK. d.fitzgerald@qub.ac.uk.
Source: Nature communications [Nat Commun] 2024 Mar 11; Vol. 15 (1), pp. 1870. Date of Electronic Publication: 2024 Mar 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Ageing impairs the regenerative capacity of regulatory T cells in mouse central nervous system remyelination.
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  Data: <searchLink fieldCode="AU" term="%22de+la+Fuente+AG%22">de la Fuente AG</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK. guzman_ale@isabial.es.; Institute for Health and Biomedical Sciences of Alicante (ISABIAL), Alicante, 03010, Spain. guzman_ale@isabial.es.; Instituto de Neurosciencias CSIC-UMH, San Juan de Alicante, Alicante, 03550, Spain. guzman_ale@isabial.es.<br /><searchLink fieldCode="AU" term="%22Dittmer+M%22">Dittmer M</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.<br /><searchLink fieldCode="AU" term="%22Heesbeen+EJ%22">Heesbeen EJ</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.; Division of Pharmacology, Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+la+Vega+Gallardo+N%22">de la Vega Gallardo N</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.<br /><searchLink fieldCode="AU" term="%22White+JA%22">White JA</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.<br /><searchLink fieldCode="AU" term="%22Young+A%22">Young A</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.<br /><searchLink fieldCode="AU" term="%22McColgan+T%22">McColgan T</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.<br /><searchLink fieldCode="AU" term="%22Dashwood+A%22">Dashwood A</searchLink>; Department of Pathology, University of Cambridge, CB2 1QP, Cambridge, UK.; Babraham Institute, CB22 3AT, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Mayne+K%22">Mayne K</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.<br /><searchLink fieldCode="AU" term="%22Cabeza-Fernández+S%22">Cabeza-Fernández S</searchLink>; Institute for Health and Biomedical Sciences of Alicante (ISABIAL), Alicante, 03010, Spain.; Instituto de Neurosciencias CSIC-UMH, San Juan de Alicante, Alicante, 03550, Spain.<br /><searchLink fieldCode="AU" term="%22Falconer+J%22">Falconer J</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.; CRUK Beatson Institute, G61 1BD, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Baena+FJ%22">Rodriguez-Baena FJ</searchLink>; Instituto de Neurosciencias CSIC-UMH, San Juan de Alicante, Alicante, 03550, Spain.<br /><searchLink fieldCode="AU" term="%22McMurran+CE%22">McMurran CE</searchLink>; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Inayatullah+M%22">Inayatullah M</searchLink>; Institute of Molecular Medicine, University of Southern Denmark, 5000, Odense, Denmark.; Danish Institute for Advanced Study (DIAS), 5230, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Rawji+KS%22">Rawji KS</searchLink>; Altos Labs - Cambridge Institute of Science, Granta Park, Cambridge, CB21 6GP, UK.<br /><searchLink fieldCode="AU" term="%22Franklin+RJM%22">Franklin RJM</searchLink>; Altos Labs - Cambridge Institute of Science, Granta Park, Cambridge, CB21 6GP, UK.<br /><searchLink fieldCode="AU" term="%22Dooley+J%22">Dooley J</searchLink>; Department of Pathology, University of Cambridge, CB2 1QP, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Liston+A%22">Liston A</searchLink>; Department of Pathology, University of Cambridge, CB2 1QP, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Ingram+RJ%22">Ingram RJ</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.<br /><searchLink fieldCode="AU" term="%22Tiwari+VK%22">Tiwari VK</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.; Institute of Molecular Medicine, University of Southern Denmark, 5000, Odense, Denmark.; Danish Institute for Advanced Study (DIAS), 5230, Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, 5000, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Penalva+R%22">Penalva R</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.<br /><searchLink fieldCode="AU" term="%22Dombrowski+Y%22">Dombrowski Y</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.<br /><searchLink fieldCode="AU" term="%22Fitzgerald+DC%22">Fitzgerald DC</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK. d.fitzgerald@qub.ac.uk.
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