View in EDS

Selective Replacement of Cholesterol with Cationic Amphiphilic Drugs Enables the Design of Lipid Nanoparticles with Improved RNA Delivery.

Saved in:
Bibliographic Details
Title: Selective Replacement of Cholesterol with Cationic Amphiphilic Drugs Enables the Design of Lipid Nanoparticles with Improved RNA Delivery.
Authors: Bogaert B; Ghent Research Group on Nanomedicines, Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium., Debisschop A; Ghent Research Group on Nanomedicines, Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium., Ehouarne T; Ghent Research Group on Nanomedicines, Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium., Van Eeckhoutte HP; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent University, C. Heymanslaan 10, 9000 Ghent, Belgium., De Volder J; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent University, C. Heymanslaan 10, 9000 Ghent, Belgium., Jacobs A; Health Unit, Flemish Institute for Technological Research (VITO), Boeretang 200, 2400 Mol, Belgium., Pottie E; Laboratory of Toxicology, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium., De Rycke R; Ghent University Expertise Center for Transmission Electron Microscopy and VIB BioImaging Core, 9000 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, VIB Center for Inflammation Research, 9052 Ghent, Belgium., Crabbé A; Laboratory of Pharmaceutical Microbiology, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium., Mestdagh P; Department of Biomolecular Medicine, OncoRNAlab, Ghent University, C. Heymanslaan 10, 9000 Ghent, Belgium., Lentacker I; Ghent Research Group on Nanomedicines, Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium., Brusselle GG; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent University, C. Heymanslaan 10, 9000 Ghent, Belgium., Stove C; Laboratory of Toxicology, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium., Verstraelen S; Health Unit, Flemish Institute for Technological Research (VITO), Boeretang 200, 2400 Mol, Belgium., Maes T; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent University, C. Heymanslaan 10, 9000 Ghent, Belgium., Bracke KR; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent University, C. Heymanslaan 10, 9000 Ghent, Belgium., De Smedt SC; Ghent Research Group on Nanomedicines, Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium., Raemdonck K; Ghent Research Group on Nanomedicines, Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.
Source: Nano letters [Nano Lett] 2024 Mar 13; Vol. 24 (10), pp. 2961-2971. Date of Electronic Publication: 2024 Mar 04.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101088070 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6992 (Electronic) Linking ISSN: 15306984 NLM ISO Abbreviation: Nano Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 38477058
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Selective Replacement of Cholesterol with Cationic Amphiphilic Drugs Enables the Design of Lipid Nanoparticles with Improved RNA Delivery.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Bogaert+B%22">Bogaert B</searchLink>; Ghent Research Group on Nanomedicines, Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Debisschop+A%22">Debisschop A</searchLink>; Ghent Research Group on Nanomedicines, Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Ehouarne+T%22">Ehouarne T</searchLink>; Ghent Research Group on Nanomedicines, Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Eeckhoutte+HP%22">Van Eeckhoutte HP</searchLink>; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent University, C. Heymanslaan 10, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Volder+J%22">De Volder J</searchLink>; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent University, C. Heymanslaan 10, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Jacobs+A%22">Jacobs A</searchLink>; Health Unit, Flemish Institute for Technological Research (VITO), Boeretang 200, 2400 Mol, Belgium.<br /><searchLink fieldCode="AU" term="%22Pottie+E%22">Pottie E</searchLink>; Laboratory of Toxicology, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Rycke+R%22">De Rycke R</searchLink>; Ghent University Expertise Center for Transmission Electron Microscopy and VIB BioImaging Core, 9000 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, VIB Center for Inflammation Research, 9052 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Crabbé+A%22">Crabbé A</searchLink>; Laboratory of Pharmaceutical Microbiology, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Mestdagh+P%22">Mestdagh P</searchLink>; Department of Biomolecular Medicine, OncoRNAlab, Ghent University, C. Heymanslaan 10, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Lentacker+I%22">Lentacker I</searchLink>; Ghent Research Group on Nanomedicines, Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Brusselle+GG%22">Brusselle GG</searchLink>; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent University, C. Heymanslaan 10, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Stove+C%22">Stove C</searchLink>; Laboratory of Toxicology, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Verstraelen+S%22">Verstraelen S</searchLink>; Health Unit, Flemish Institute for Technological Research (VITO), Boeretang 200, 2400 Mol, Belgium.<br /><searchLink fieldCode="AU" term="%22Maes+T%22">Maes T</searchLink>; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent University, C. Heymanslaan 10, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Bracke+KR%22">Bracke KR</searchLink>; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent University, C. Heymanslaan 10, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Smedt+SC%22">De Smedt SC</searchLink>; Ghent Research Group on Nanomedicines, Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Raemdonck+K%22">Raemdonck K</searchLink>; Ghent Research Group on Nanomedicines, Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101088070%22">Nano letters</searchLink> [Nano Lett] 2024 Mar 13; Vol. 24 (10), pp. 2961-2971. <i>Date of Electronic Publication: </i>2024 Mar 04.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101088070 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1530-6992 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215306984%22">15306984 </searchLink><i>NLM ISO Abbreviation: </i>Nano Lett <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=38477058
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1021/acs.nanolett.3c03345
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 2961
    Titles:
      – TitleFull: Selective Replacement of Cholesterol with Cationic Amphiphilic Drugs Enables the Design of Lipid Nanoparticles with Improved RNA Delivery.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Bogaert B
      – PersonEntity:
          Name:
            NameFull: Debisschop A
      – PersonEntity:
          Name:
            NameFull: Ehouarne T
      – PersonEntity:
          Name:
            NameFull: Van Eeckhoutte HP
      – PersonEntity:
          Name:
            NameFull: De Volder J
      – PersonEntity:
          Name:
            NameFull: Jacobs A
      – PersonEntity:
          Name:
            NameFull: Pottie E
      – PersonEntity:
          Name:
            NameFull: De Rycke R
      – PersonEntity:
          Name:
            NameFull: Crabbé A
      – PersonEntity:
          Name:
            NameFull: Mestdagh P
      – PersonEntity:
          Name:
            NameFull: Lentacker I
      – PersonEntity:
          Name:
            NameFull: Brusselle GG
      – PersonEntity:
          Name:
            NameFull: Stove C
      – PersonEntity:
          Name:
            NameFull: Verstraelen S
      – PersonEntity:
          Name:
            NameFull: Maes T
      – PersonEntity:
          Name:
            NameFull: Bracke KR
      – PersonEntity:
          Name:
            NameFull: De Smedt SC
      – PersonEntity:
          Name:
            NameFull: Raemdonck K
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 13
              M: 03
              Text: 2024 Mar 13
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-electronic
              Value: 1530-6992
          Numbering:
            – Type: volume
              Value: 24
            – Type: issue
              Value: 10
          Titles:
            – TitleFull: Nano letters
              Type: main
ResultId 1