Adjunctive Pascolizumab in Rifampicin-Susceptible Pulmonary Tuberculosis: Proof-of-Concept, Partially-Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Trial.

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Title: Adjunctive Pascolizumab in Rifampicin-Susceptible Pulmonary Tuberculosis: Proof-of-Concept, Partially-Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Trial.
Authors: Paton NI; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Infectious Diseases Translational Research Programme, National University of Singapore, Singapore, Singapore.; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., Gurumurthy M; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lu Q; Singapore Clinical Research Institute, Singapore, Singapore, Singapore., Leek F; Clinical Imaging Research Centre, National University of Singapore, Singapore, Singapore., Kwan P; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Koh HWL; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Molton J; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Mortera L; Quezon Institute, Quezon City, Philippines., Naval S; Lung Centre of the Philippines, Quezon City, Philippines., Bakar ZA; Institute of Respiratory Medicine, Kuala Lumpur, Malaysia., Pang YK; University of Malaya Medical Centre, Kuala Lumpur, Malaysia., Lum L; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lim TK; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Cross GB; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lekurwale G; Singapore Clinical Research Institute, Singapore, Singapore, Singapore., Choi H; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Au V; Institute of Cellular and Molecular Biology, Singapore, Singapore., Connolly J; Institute of Cellular and Molecular Biology, Singapore, Singapore., Hibberd M; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.; Department of Microbiology, National University of Singapore, Singapore, Singapore., Green JA; GSK, Greenford, United Kingdom.
Corporate Authors: Pascolizumab Tuberculosis Trial Team
Source: The Journal of infectious diseases [J Infect Dis] 2024 Sep 23; Vol. 230 (3), pp. 590-597.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Adjunctive Pascolizumab in Rifampicin-Susceptible Pulmonary Tuberculosis: Proof-of-Concept, Partially-Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Trial.
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  Data: <searchLink fieldCode="AU" term="%22Paton+NI%22">Paton NI</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Infectious Diseases Translational Research Programme, National University of Singapore, Singapore, Singapore.; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gurumurthy+M%22">Gurumurthy M</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lu+Q%22">Lu Q</searchLink>; Singapore Clinical Research Institute, Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Leek+F%22">Leek F</searchLink>; Clinical Imaging Research Centre, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Kwan+P%22">Kwan P</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Koh+HWL%22">Koh HWL</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Molton+J%22">Molton J</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Mortera+L%22">Mortera L</searchLink>; Quezon Institute, Quezon City, Philippines.<br /><searchLink fieldCode="AU" term="%22Naval+S%22">Naval S</searchLink>; Lung Centre of the Philippines, Quezon City, Philippines.<br /><searchLink fieldCode="AU" term="%22Bakar+ZA%22">Bakar ZA</searchLink>; Institute of Respiratory Medicine, Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Pang+YK%22">Pang YK</searchLink>; University of Malaya Medical Centre, Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Lum+L%22">Lum L</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lim+TK%22">Lim TK</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Cross+GB%22">Cross GB</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lekurwale+G%22">Lekurwale G</searchLink>; Singapore Clinical Research Institute, Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Choi+H%22">Choi H</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Au+V%22">Au V</searchLink>; Institute of Cellular and Molecular Biology, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Connolly+J%22">Connolly J</searchLink>; Institute of Cellular and Molecular Biology, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Hibberd+M%22">Hibberd M</searchLink>; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.; Department of Microbiology, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Green+JA%22">Green JA</searchLink>; GSK, Greenford, United Kingdom.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0413675 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1537-6613 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200221899%22">00221899 </searchLink><i>NLM ISO Abbreviation: </i>J Infect Dis <i>Subsets: </i>MEDLINE
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