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AMPK inhibition sensitizes acute leukemia cells to BH3 mimetic-induced cell death.

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Title: AMPK inhibition sensitizes acute leukemia cells to BH3 mimetic-induced cell death.
Authors: Jia J; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; University of Science and Technology of China, Hefei, 230026, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Ji W; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; University of Science and Technology of China, Hefei, 230026, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Saliba AN; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA., Csizmar CM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA.; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA., Ye K; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Hu L; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; University of Science and Technology of China, Hefei, 230026, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Peterson KL; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Schneider PA; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Meng XW; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Venkatachalam A; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Patnaik MM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA., Webster JA; Adult Leukemia Program, Sidney Kimmel Cancer Center at Johns Hopkins, Baltimore, MD, 21287, USA., Smith BD; Adult Leukemia Program, Sidney Kimmel Cancer Center at Johns Hopkins, Baltimore, MD, 21287, USA., Ghiaur G; Adult Leukemia Program, Sidney Kimmel Cancer Center at Johns Hopkins, Baltimore, MD, 21287, USA., Wu X; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA., Zhong J; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA., Pandey A; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA.; Manipal Academy of Higher Education, Manipal, 576104, Kamataka, India., Flatten KS; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Deng Q; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Wang H; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Kaufmann SH; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu.; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu., Dai H; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China. daih@cmpt.ac.cn.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China. daih@cmpt.ac.cn.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA. daih@cmpt.ac.cn.
Source: Cell death and differentiation [Cell Death Differ] 2024 Apr; Vol. 31 (4), pp. 405-416. Date of Electronic Publication: 2024 Mar 27.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: AMPK inhibition sensitizes acute leukemia cells to BH3 mimetic-induced cell death.
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  Data: <searchLink fieldCode="AU" term="%22Jia+J%22">Jia J</searchLink>; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; University of Science and Technology of China, Hefei, 230026, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China.<br /><searchLink fieldCode="AU" term="%22Ji+W%22">Ji W</searchLink>; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; University of Science and Technology of China, Hefei, 230026, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China.<br /><searchLink fieldCode="AU" term="%22Saliba+AN%22">Saliba AN</searchLink>; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Csizmar+CM%22">Csizmar CM</searchLink>; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA.; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Ye+K%22">Ye K</searchLink>; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China.<br /><searchLink fieldCode="AU" term="%22Hu+L%22">Hu L</searchLink>; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; University of Science and Technology of China, Hefei, 230026, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China.<br /><searchLink fieldCode="AU" term="%22Peterson+KL%22">Peterson KL</searchLink>; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Schneider+PA%22">Schneider PA</searchLink>; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Meng+XW%22">Meng XW</searchLink>; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Venkatachalam+A%22">Venkatachalam A</searchLink>; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Patnaik+MM%22">Patnaik MM</searchLink>; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Webster+JA%22">Webster JA</searchLink>; Adult Leukemia Program, Sidney Kimmel Cancer Center at Johns Hopkins, Baltimore, MD, 21287, USA.<br /><searchLink fieldCode="AU" term="%22Smith+BD%22">Smith BD</searchLink>; Adult Leukemia Program, Sidney Kimmel Cancer Center at Johns Hopkins, Baltimore, MD, 21287, USA.<br /><searchLink fieldCode="AU" term="%22Ghiaur+G%22">Ghiaur G</searchLink>; Adult Leukemia Program, Sidney Kimmel Cancer Center at Johns Hopkins, Baltimore, MD, 21287, USA.<br /><searchLink fieldCode="AU" term="%22Wu+X%22">Wu X</searchLink>; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Zhong+J%22">Zhong J</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Pandey+A%22">Pandey A</searchLink>; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA.; Manipal Academy of Higher Education, Manipal, 576104, Kamataka, India.<br /><searchLink fieldCode="AU" term="%22Flatten+KS%22">Flatten KS</searchLink>; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Deng+Q%22">Deng Q</searchLink>; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China.<br /><searchLink fieldCode="AU" term="%22Kaufmann+SH%22">Kaufmann SH</searchLink>; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu.; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu.<br /><searchLink fieldCode="AU" term="%22Dai+H%22">Dai H</searchLink>; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China. daih@cmpt.ac.cn.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China. daih@cmpt.ac.cn.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA. daih@cmpt.ac.cn.
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  Data: <searchLink fieldCode="JN" term="%229437445%22">Cell death and differentiation</searchLink> [Cell Death Differ] 2024 Apr; Vol. 31 (4), pp. 405-416. <i>Date of Electronic Publication: </i>2024 Mar 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9437445 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5403 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213509047%22">13509047 </searchLink><i>NLM ISO Abbreviation: </i>Cell Death Differ <i>Subsets: </i>MEDLINE
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