PCSK9 stimulates Syk, PKCδ, and NF-κB, leading to atherosclerosis progression independently of LDL receptor.
Saved in:
| Title: | PCSK9 stimulates Syk, PKCδ, and NF-κB, leading to atherosclerosis progression independently of LDL receptor. |
|---|---|
| Authors: | Shin D; Center of CBT (Cell and BioTherapy), Seoul National University Hospital, Seoul, Republic of Korea.; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Kim S; Center of CBT (Cell and BioTherapy), Seoul National University Hospital, Seoul, Republic of Korea.; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Lee H; Center of CBT (Cell and BioTherapy), Seoul National University Hospital, Seoul, Republic of Korea.; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Lee HC; Center of CBT (Cell and BioTherapy), Seoul National University Hospital, Seoul, Republic of Korea.; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Lee J; Center of CBT (Cell and BioTherapy), Seoul National University Hospital, Seoul, Republic of Korea.; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Park HW; Center of CBT (Cell and BioTherapy), Seoul National University Hospital, Seoul, Republic of Korea.; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Program in Stem Cell Biology, Seoul National University College of Medicine, Seoul, Republic of Korea., Fukai M; Center of CBT (Cell and BioTherapy), Seoul National University Hospital, Seoul, Republic of Korea.; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Choi E; Center of CBT (Cell and BioTherapy), Seoul National University Hospital, Seoul, Republic of Korea.; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Choi S; Center of CBT (Cell and BioTherapy), Seoul National University Hospital, Seoul, Republic of Korea.; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Koo BJ; Center of CBT (Cell and BioTherapy), Seoul National University Hospital, Seoul, Republic of Korea.; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Yu JH; Center of CBT (Cell and BioTherapy), Seoul National University Hospital, Seoul, Republic of Korea.; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., No G; Center of CBT (Cell and BioTherapy), Seoul National University Hospital, Seoul, Republic of Korea.; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Cho S; Center of CBT (Cell and BioTherapy), Seoul National University Hospital, Seoul, Republic of Korea.; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Program in Stem Cell Biology, Seoul National University College of Medicine, Seoul, Republic of Korea., Kim CW; Department of Preclinical Trial, Laboratory Animal Center, Osong Medical Innovation Foundation (KBIO), Cheongju, Chungbuk, Republic of Korea., Han D; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Jang HD; Center of CBT (Cell and BioTherapy), Seoul National University Hospital, Seoul, Republic of Korea. 65765@snuh.org.; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea. 65765@snuh.org., Kim HS; Center of CBT (Cell and BioTherapy), Seoul National University Hospital, Seoul, Republic of Korea. hyosoo@snu.ac.kr.; Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea. hyosoo@snu.ac.kr.; Program in Stem Cell Biology, Seoul National University College of Medicine, Seoul, Republic of Korea. hyosoo@snu.ac.kr.; Cardiovascular Center & Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea. hyosoo@snu.ac.kr. |
| Source: | Nature communications [Nat Commun] 2024 Mar 30; Vol. 15 (1), pp. 2789. Date of Electronic Publication: 2024 Mar 30. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
Be the first to leave a comment!
