Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model.
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| Title: | Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model. |
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| Authors: | Hou J; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA., Chen Y; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA.; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University in St. Louis, St. Louis, MO 63110, USA., Cai Z; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA., Heo GS; Department of Radiology, Washington University in St. Louis, St. Louis, MO 63110, USA., Yuede CM; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA., Wang Z; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA., Lin K; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA., Saadi F; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University in St. Louis, St. Louis, MO 63110, USA., Trsan T; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA., Nguyen AT; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Constantopoulos E; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Larsen RA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Zhu Y; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA., Wagner ND; Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63110, USA., McLaughlin N; Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63110, USA., Kuang XC; Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63110, USA., Barrow AD; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Parkville, VIC 3000, Australia., Li D; Division of Nephrology, Department of Medicine, Washington University, St. Louis, MO 63110, USA., Zhou Y; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA., Wang S; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pok Fu Lam, Hong Kong, China., Gilfillan S; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA., Gross ML; Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63110, USA., Brioschi S; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA., Liu Y; Department of Radiology, Washington University in St. Louis, St. Louis, MO 63110, USA., Holtzman DM; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University in St. Louis, St. Louis, MO 63110, USA., Colonna M; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA. |
| Source: | Science translational medicine [Sci Transl Med] 2024 Apr 03; Vol. 16 (741), pp. eadj9052. Date of Electronic Publication: 2024 Apr 03. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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