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Safety and Preliminary Efficacy of Pembrolizumab Following Transarterial Chemoembolization for Hepatocellular Carcinoma: The PETAL Phase Ib Study.

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Title: Safety and Preliminary Efficacy of Pembrolizumab Following Transarterial Chemoembolization for Hepatocellular Carcinoma: The PETAL Phase Ib Study.
Authors: Pinato DJ; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy., D'Alessio A; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy., Fulgenzi CAM; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom., Schlaak AE; Department of Internal Medicine, University Hospital Freiburg, Freiburg, Germany., Celsa C; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.; Section of Gastroenterology and Hepatology, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, PROMISE, University of Palermo, Palermo, Italy., Killmer S; Department of Internal Medicine, University Hospital Freiburg, Freiburg, Germany., Blanco JM; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, London, United Kingdom., Ward C; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom., Stikas CV; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom., Openshaw MR; Institute of Cancer and Genomics Sciences, University of Birmingham, Birmingham, United Kingdom., Acuti N; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom., Nteliopoulos G; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom., Balcells C; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom., Keun HC; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom., Goldin RD; Centre for Pathology, Imperial College London, Charing Cross Hospital, London, United Kingdom., Ross PJ; Department of Medical Oncology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.; King's College Hospital NHS Foundation Trust, London, United Kingdom., Cortellini A; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.; Division of Medical Oncology, Policlinico Universitario Campus Bio-Medico, Rome, Italy., Thomas R; Interventional Radiology, Imperial College NHS Trust, Hammersmith Hospital, London, United Kingdom., Young AM; Department of Medical Oncology, St Georges University Hospitals, NHS Foundation Trust, St George's University Hospitals NHS Foundation Trust, London, United Kingdom., Danckert N; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, London, United Kingdom., Tait P; Interventional Radiology, Imperial College NHS Trust, Hammersmith Hospital, London, United Kingdom., Marchesi JR; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, London, United Kingdom., Bengsch B; Department of Internal Medicine, University Hospital Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany, partner site Freiburg., Sharma R; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Jun 03; Vol. 30 (11), pp. 2433-2443.
Publication Type: Journal Article; Clinical Trial, Phase I; Multicenter Study
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
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  Data: Safety and Preliminary Efficacy of Pembrolizumab Following Transarterial Chemoembolization for Hepatocellular Carcinoma: The PETAL Phase Ib Study.
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  Data: <searchLink fieldCode="AU" term="%22Pinato+DJ%22">Pinato DJ</searchLink>; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy.<br /><searchLink fieldCode="AU" term="%22D'Alessio+A%22">D'Alessio A</searchLink>; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy.<br /><searchLink fieldCode="AU" term="%22Fulgenzi+CAM%22">Fulgenzi CAM</searchLink>; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Schlaak+AE%22">Schlaak AE</searchLink>; Department of Internal Medicine, University Hospital Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Celsa+C%22">Celsa C</searchLink>; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.; Section of Gastroenterology and Hepatology, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, PROMISE, University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Killmer+S%22">Killmer S</searchLink>; Department of Internal Medicine, University Hospital Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Blanco+JM%22">Blanco JM</searchLink>; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ward+C%22">Ward C</searchLink>; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Stikas+CV%22">Stikas CV</searchLink>; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Openshaw+MR%22">Openshaw MR</searchLink>; Institute of Cancer and Genomics Sciences, University of Birmingham, Birmingham, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Acuti+N%22">Acuti N</searchLink>; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Nteliopoulos+G%22">Nteliopoulos G</searchLink>; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Balcells+C%22">Balcells C</searchLink>; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Keun+HC%22">Keun HC</searchLink>; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Goldin+RD%22">Goldin RD</searchLink>; Centre for Pathology, Imperial College London, Charing Cross Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ross+PJ%22">Ross PJ</searchLink>; Department of Medical Oncology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.; King's College Hospital NHS Foundation Trust, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cortellini+A%22">Cortellini A</searchLink>; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.; Division of Medical Oncology, Policlinico Universitario Campus Bio-Medico, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Thomas+R%22">Thomas R</searchLink>; Interventional Radiology, Imperial College NHS Trust, Hammersmith Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Young+AM%22">Young AM</searchLink>; Department of Medical Oncology, St Georges University Hospitals, NHS Foundation Trust, St George's University Hospitals NHS Foundation Trust, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Danckert+N%22">Danckert N</searchLink>; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Tait+P%22">Tait P</searchLink>; Interventional Radiology, Imperial College NHS Trust, Hammersmith Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Marchesi+JR%22">Marchesi JR</searchLink>; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Bengsch+B%22">Bengsch B</searchLink>; Department of Internal Medicine, University Hospital Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany, partner site Freiburg.<br /><searchLink fieldCode="AU" term="%22Sharma+R%22">Sharma R</searchLink>; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.
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