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Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies.

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Title: Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies.
Authors: Wirchnianski AS; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America., Nyakatura EK; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America., Herbert AS; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.; The Geneva Foundation, Tacoma, Washington, United States of America., Kuehne AI; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Abbasi SA; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.; The Geneva Foundation, Tacoma, Washington, United States of America., Florez C; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.; The Geneva Foundation, Tacoma, Washington, United States of America., Storm N; Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America., McKay LGA; Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America., Dailey L; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America., Kuang E; Mapp Biopharmaceutical Inc., San Diego, California, United States of America., Abelson DM; Mapp Biopharmaceutical Inc., San Diego, California, United States of America., Wec AZ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America., Chakraborti S; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America., Holtsberg FW; Integrated BioTherapeutics, Inc., Rockville, Maryland, United States of America., Shulenin S; Integrated BioTherapeutics, Inc., Rockville, Maryland, United States of America., Bornholdt ZA; Mapp Biopharmaceutical Inc., San Diego, California, United States of America., Aman MJ; Integrated BioTherapeutics, Inc., Rockville, Maryland, United States of America., Honko AN; Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America., Griffiths A; Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America., Dye JM; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America., Lai JR; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Source: PLoS pathogens [PLoS Pathog] 2024 Apr 11; Vol. 20 (4), pp. e1012134. Date of Electronic Publication: 2024 Apr 11 (Print Publication: 2024).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies.
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  Data: <searchLink fieldCode="AU" term="%22Wirchnianski+AS%22">Wirchnianski AS</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Nyakatura+EK%22">Nyakatura EK</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Herbert+AS%22">Herbert AS</searchLink>; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.; The Geneva Foundation, Tacoma, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Kuehne+AI%22">Kuehne AI</searchLink>; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Abbasi+SA%22">Abbasi SA</searchLink>; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.; The Geneva Foundation, Tacoma, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Florez+C%22">Florez C</searchLink>; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.; The Geneva Foundation, Tacoma, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Storm+N%22">Storm N</searchLink>; Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22McKay+LGA%22">McKay LGA</searchLink>; Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Dailey+L%22">Dailey L</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Kuang+E%22">Kuang E</searchLink>; Mapp Biopharmaceutical Inc., San Diego, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Abelson+DM%22">Abelson DM</searchLink>; Mapp Biopharmaceutical Inc., San Diego, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Wec+AZ%22">Wec AZ</searchLink>; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Chakraborti+S%22">Chakraborti S</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Holtsberg+FW%22">Holtsberg FW</searchLink>; Integrated BioTherapeutics, Inc., Rockville, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Shulenin+S%22">Shulenin S</searchLink>; Integrated BioTherapeutics, Inc., Rockville, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Bornholdt+ZA%22">Bornholdt ZA</searchLink>; Mapp Biopharmaceutical Inc., San Diego, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Aman+MJ%22">Aman MJ</searchLink>; Integrated BioTherapeutics, Inc., Rockville, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Honko+AN%22">Honko AN</searchLink>; Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Griffiths+A%22">Griffiths A</searchLink>; Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Dye+JM%22">Dye JM</searchLink>; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Chandran+K%22">Chandran K</searchLink>; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Lai+JR%22">Lai JR</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.
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